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Items: 1 to 20 of 92

1.

Influenza A virus protein PB1-F2 translocates into mitochondria via Tom40 channels and impairs innate immunity.

Yoshizumi T, Ichinohe T, Sasaki O, Otera H, Kawabata S, Mihara K, Koshiba T.

Nat Commun. 2014 Aug 20;5:4713. doi: 10.1038/ncomms5713.

PMID:
25140902
2.

Activation of the NLRP3 inflammasome by IAV virulence protein PB1-F2 contributes to severe pathophysiology and disease.

McAuley JL, Tate MD, MacKenzie-Kludas CJ, Pinar A, Zeng W, Stutz A, Latz E, Brown LE, Mansell A.

PLoS Pathog. 2013;9(5):e1003392. doi: 10.1371/journal.ppat.1003392. Epub 2013 May 30.

3.

NLRX1 prevents mitochondrial induced apoptosis and enhances macrophage antiviral immunity by interacting with influenza virus PB1-F2 protein.

Jaworska J, Coulombe F, Downey J, Tzelepis F, Shalaby K, Tattoli I, Berube J, Rousseau S, Martin JG, Girardin SE, McCullers JA, Divangahi M.

Proc Natl Acad Sci U S A. 2014 May 20;111(20):E2110-9. doi: 10.1073/pnas.1322118111. Epub 2014 May 5.

4.

PB1-F2 Peptide Derived from Avian Influenza A Virus H7N9 Induces Inflammation via Activation of the NLRP3 Inflammasome.

Pinar A, Dowling JK, Bitto NJ, Robertson AA, Latz E, Stewart CR, Drummond GR, Cooper MA, McAuley JL, Tate MD, Mansell A.

J Biol Chem. 2017 Jan 20;292(3):826-836. doi: 10.1074/jbc.M116.756379. Epub 2016 Dec 2.

5.

Type I IFN triggers RIG-I/TLR3/NLRP3-dependent inflammasome activation in influenza A virus infected cells.

Pothlichet J, Meunier I, Davis BK, Ting JP, Skamene E, von Messling V, Vidal SM.

PLoS Pathog. 2013;9(4):e1003256. doi: 10.1371/journal.ppat.1003256. Epub 2013 Apr 11.

6.

Mitochondrial protein mitofusin 2 is required for NLRP3 inflammasome activation after RNA virus infection.

Ichinohe T, Yamazaki T, Koshiba T, Yanagi Y.

Proc Natl Acad Sci U S A. 2013 Oct 29;110(44):17963-8. doi: 10.1073/pnas.1312571110. Epub 2013 Oct 14.

7.
8.

Influenza virus protein PB1-F2 inhibits the induction of type I interferon by binding to MAVS and decreasing mitochondrial membrane potential.

Varga ZT, Grant A, Manicassamy B, Palese P.

J Virol. 2012 Aug;86(16):8359-66. doi: 10.1128/JVI.01122-12. Epub 2012 Jun 6.

9.

Response of host inflammasomes to viral infection.

Chen IY, Ichinohe T.

Trends Microbiol. 2015 Jan;23(1):55-63. doi: 10.1016/j.tim.2014.09.007. Epub 2014 Oct 22. Review.

PMID:
25456015
10.

Downregulation of microRNA miR-526a by enterovirus inhibits RIG-I-dependent innate immune response.

Xu C, He X, Zheng Z, Zhang Z, Wei C, Guan K, Hou L, Zhang B, Zhu L, Cao Y, Zhang Y, Cao Y, Ma S, Wang P, Zhang P, Xu Q, Ling Y, Yang X, Zhong H.

J Virol. 2014 Oct;88(19):11356-68. doi: 10.1128/JVI.01400-14. Epub 2014 Jul 23.

11.

PB1-F2 modulates early host responses but does not affect the pathogenesis of H1N1 seasonal influenza virus.

Meunier I, von Messling V.

J Virol. 2012 Apr;86(8):4271-8. doi: 10.1128/JVI.07243-11. Epub 2012 Feb 8.

12.

The microRNA miR-485 targets host and influenza virus transcripts to regulate antiviral immunity and restrict viral replication.

Ingle H, Kumar S, Raut AA, Mishra A, Kulkarni DD, Kameyama T, Takaoka A, Akira S, Kumar H.

Sci Signal. 2015 Dec 8;8(406):ra126. doi: 10.1126/scisignal.aab3183.

PMID:
26645583
13.

Prevalence of PB1-F2 of influenza A viruses.

Zell R, Krumbholz A, Eitner A, Krieg R, Halbhuber KJ, Wutzler P.

J Gen Virol. 2007 Feb;88(Pt 2):536-46.

PMID:
17251572
14.

Influenza A virus protein PB1-F2 from different strains shows distinct structural signatures.

Solbak SM, Sharma A, Bruns K, Röder R, Mitzner D, Hahn F, Niebert R, Vedeler A, Henklein P, Henklein P, Schubert U, Wray V, Fossen T.

Biochim Biophys Acta. 2013 Feb;1834(2):568-82. doi: 10.1016/j.bbapap.2012.11.009. Epub 2012 Dec 7.

PMID:
23220419
15.

Mitochondrial control of the NLRP3 inflammasome.

Kepp O, Galluzzi L, Kroemer G.

Nat Immunol. 2011 Mar;12(3):199-200. doi: 10.1038/ni0311-199. No abstract available.

PMID:
21321591
16.

Influenza A virus protein PB1-F2 exacerbates IFN-beta expression of human respiratory epithelial cells.

Le Goffic R, Bouguyon E, Chevalier C, Vidic J, Da Costa B, Leymarie O, Bourdieu C, Decamps L, Dhorne-Pollet S, Delmas B.

J Immunol. 2010 Oct 15;185(8):4812-23. doi: 10.4049/jimmunol.0903952. Epub 2010 Sep 15.

17.

Surveillance in Eastern India (2007-2009) revealed reassortment event involving NS and PB1-F2 gene segments among co-circulating influenza A subtypes.

Sarkar M, Chanda S, Chakrabarti S, Mazumdar J, Ganguly A, Chadha MS, Mishra AC, Chawla-Sarkar M.

Virol J. 2012 Jan 5;9:3. doi: 10.1186/1743-422X-9-3.

18.

Transcriptomic analysis of host immune and cell death responses associated with the influenza A virus PB1-F2 protein.

Le Goffic R, Leymarie O, Chevalier C, Rebours E, Da Costa B, Vidic J, Descamps D, Sallenave JM, Rauch M, Samson M, Delmas B.

PLoS Pathog. 2011 Aug;7(8):e1002202. doi: 10.1371/journal.ppat.1002202. Epub 2011 Aug 25.

19.

Innate immune sensing of modified vaccinia virus Ankara (MVA) is mediated by TLR2-TLR6, MDA-5 and the NALP3 inflammasome.

Delaloye J, Roger T, Steiner-Tardivel QG, Le Roy D, Knaup Reymond M, Akira S, Petrilli V, Gomez CE, Perdiguero B, Tschopp J, Pantaleo G, Esteban M, Calandra T.

PLoS Pathog. 2009 Jun;5(6):e1000480. doi: 10.1371/journal.ppat.1000480. Epub 2009 Jun 19.

20.

Mitochondrial targeting sequence of the influenza A virus PB1-F2 protein and its function in mitochondria.

Yamada H, Chounan R, Higashi Y, Kurihara N, Kido H.

FEBS Lett. 2004 Dec 17;578(3):331-6.

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