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Items: 1 to 20 of 144

1.

7,8-dihydroxyflavone protects PC12 cells against 6-hydroxydopamine-induced cell death through modulating PI3K/Akt and JNK pathways.

Han XH, Cheng MN, Chen L, Fang H, Wang LJ, Li XT, Qu ZQ.

Neurosci Lett. 2014 Oct 3;581:85-8. doi: 10.1016/j.neulet.2014.08.016. Epub 2014 Aug 17.

PMID:
25139527
2.

Antioxidant action of 7,8-dihydroxyflavone protects PC12 cells against 6-hydroxydopamine-induced cytotoxicity.

Han X, Zhu S, Wang B, Chen L, Li R, Yao W, Qu Z.

Neurochem Int. 2014 Jan;64:18-23. doi: 10.1016/j.neuint.2013.10.018. Epub 2013 Nov 9.

PMID:
24220540
3.

Protective effect of hydrogen sulphide against 6-OHDA-induced cell injury in SH-SY5Y cells involves PKC/PI3K/Akt pathway.

Tiong CX, Lu M, Bian JS.

Br J Pharmacol. 2010 Sep;161(2):467-80. doi: 10.1111/j.1476-5381.2010.00887.x. Erratum in: Br J Pharmacol. 2013 Apr;168(8):2011-2.

4.

Neurotrophin-3 reduces apoptosis induced by 6-OHDA in PC12 cells through Akt signaling pathway.

Li Z, Hu Y, Zhu Q, Zhu J.

Int J Dev Neurosci. 2008 Oct;26(6):635-40. doi: 10.1016/j.ijdevneu.2008.03.009. Epub 2008 Apr 4.

PMID:
18462913
5.

EPO-dependent activation of PI3K/Akt/FoxO3a signalling mediates neuroprotection in in vitro and in vivo models of Parkinson's disease.

Jia Y, Mo SJ, Feng QQ, Zhan ML, OuYang LS, Chen JC, Ma YX, Wu JJ, Lei WL.

J Mol Neurosci. 2014 May;53(1):117-24. doi: 10.1007/s12031-013-0208-0. Epub 2014 Jan 4.

PMID:
24390959
6.

Ginsenoside Rg2 protects PC12 cells against β-amyloid25-35-induced apoptosis via the phosphoinositide 3-kinase/Akt pathway.

Cui J, Wang J, Zheng M, Gou D, Liu C, Zhou Y.

Chem Biol Interact. 2017 Sep 25;275:152-161. doi: 10.1016/j.cbi.2017.07.021. Epub 2017 Jul 26.

PMID:
28756148
7.

Ginsenoside Rg1 protects against 6-OHDA-induced toxicity in MES23.5 cells via Akt and ERK signaling pathways.

Ge KL, Chen WF, Xie JX, Wong MS.

J Ethnopharmacol. 2010 Jan 8;127(1):118-23. doi: 10.1016/j.jep.2009.09.038. Epub 2009 Sep 30.

PMID:
19799986
8.

Sulfatase 2 protects hepatocellular carcinoma cells against apoptosis induced by the PI3K inhibitor LY294002 and ERK and JNK kinase inhibitors.

Lai JP, Sandhu DS, Yu C, Moser CD, Hu C, Shire AM, Aderca I, Murphy LM, Adjei AA, Sanderson S, Roberts LR.

Liver Int. 2010 Nov;30(10):1522-8. doi: 10.1111/j.1478-3231.2010.02336.x. Epub 2010 Sep 8.

9.

Simvastatin induces neuroprotection in 6-OHDA-lesioned PC12 via the PI3K/AKT/caspase 3 pathway and anti-inflammatory responses.

Xu YQ, Long L, Yan JQ, Wei L, Pan MQ, Gao HM, Zhou P, Liu M, Zhu CS, Tang BS, Wang Q.

CNS Neurosci Ther. 2013 Mar;19(3):170-7. doi: 10.1111/cns.12053. Epub 2012 Dec 28.

PMID:
23279934
10.

Apelin-13 protects the brain against ischemia/reperfusion injury through activating PI3K/Akt and ERK1/2 signaling pathways.

Yang Y, Zhang X, Cui H, Zhang C, Zhu C, Li L.

Neurosci Lett. 2014 May 7;568:44-9. doi: 10.1016/j.neulet.2014.03.037. Epub 2014 Mar 29.

PMID:
24686182
11.

Lithium ions attenuate serum-deprivation-induced apoptosis in PC12 cells through regulation of the Akt/FoxO1 signaling pathways.

Zeng Z, Wang H, Shang F, Zhou L, Little PJ, Quirion R, Zheng W.

Psychopharmacology (Berl). 2016 Mar;233(5):785-94. doi: 10.1007/s00213-015-4168-7. Epub 2015 Dec 2.

PMID:
26626328
12.

Arylpiperazine-mediated activation of Akt protects SH-SY5Y neuroblastoma cells from 6-hydroxydopamine-induced apoptotic and autophagic death.

Tovilovic G, Zogovic N, Soskic V, Schrattenholz A, Kostic-Rajacic S, Misirkic-Marjanovic M, Janjetovic K, Vucicevic L, Arsikin K, Harhaji-Trajkovic L, Trajkovic V.

Neuropharmacology. 2013 Sep;72:224-35. doi: 10.1016/j.neuropharm.2013.04.037. Epub 2013 May 3.

PMID:
23643751
13.

Guanosine protects glial cells against 6-hydroxydopamine toxicity.

Giuliani P, Ballerini P, Buccella S, Ciccarelli R, Rathbone MP, Romano S, D'Alimonte I, Caciagli F, Di Iorio P, Pokorski M.

Adv Exp Med Biol. 2015;837:23-33. doi: 10.1007/5584_2014_73.

PMID:
25310956
14.

7,8-Dihydroxyflavone leads to survival of cultured embryonic motoneurons by activating intracellular signaling pathways.

Tsai T, Klausmeyer A, Conrad R, Gottschling C, Leo M, Faissner A, Wiese S.

Mol Cell Neurosci. 2013 Sep;56:18-28. doi: 10.1016/j.mcn.2013.02.007. Epub 2013 Mar 14.

PMID:
23500004
15.

Eucommia ulmoides Oliv. bark. attenuates 6-hydroxydopamine-induced neuronal cell death through inhibition of oxidative stress in SH-SY5Y cells.

Kwon SH, Ma SX, Hong SI, Kim SY, Lee SY, Jang CG.

J Ethnopharmacol. 2014 Feb 27;152(1):173-82. doi: 10.1016/j.jep.2013.12.048. Epub 2014 Jan 15.

PMID:
24440915
16.

Danshensu protects against 6-hydroxydopamine-induced damage of PC12 cells in vitro and dopaminergic neurons in zebrafish.

Chong CM, Zhou ZY, Razmovski-Naumovski V, Cui GZ, Zhang LQ, Sa F, Hoi PM, Chan K, Lee SM.

Neurosci Lett. 2013 May 24;543:121-5. doi: 10.1016/j.neulet.2013.02.069. Epub 2013 Apr 3.

PMID:
23562886
17.

Paeoniflorin inhibition of 6-hydroxydopamine-induced apoptosis in PC12 cells via suppressing reactive oxygen species-mediated PKCδ/NF-κB pathway.

Dong H, Li R, Yu C, Xu T, Zhang X, Dong M.

Neuroscience. 2015 Jan 29;285:70-80. doi: 10.1016/j.neuroscience.2014.11.008. Epub 2014 Nov 18.

PMID:
25446358
18.

Reversal of boswellic acid analog BA145 induced caspase dependent apoptosis by PI3K inhibitor LY294002 and MEK inhibitor PD98059.

Pathania AS, Joshi A, Kumar S, Guru SK, Bhushan S, Sharma PR, Bhat WW, Saxena AK, Singh J, Shah BA, Andotra SS, Taneja SC, Malik FA, Kumar A.

Apoptosis. 2013 Dec;18(12):1561-73. doi: 10.1007/s10495-013-0889-4.

PMID:
23948751
19.

Induction of Pi form of glutathione S-transferase by carnosic acid is mediated through PI3K/Akt/NF-κB pathway and protects against neurotoxicity.

Lin CY, Chen JH, Fu RH, Tsai CW.

Chem Res Toxicol. 2014 Nov 17;27(11):1958-66. doi: 10.1021/tx5003063. Epub 2014 Oct 13.

PMID:
25271104
20.

Resveratrol protects PC12 cells from high glucose-induced neurotoxicity via PI3K/Akt/FoxO3a pathway.

Liu MH, Yuan C, He J, Tan TP, Wu SJ, Fu HY, Liu J, Yu S, Chen YD, Le QF, Tian W, Hu HJ, Zhang Y, Lin XL.

Cell Mol Neurobiol. 2015 May;35(4):513-22. doi: 10.1007/s10571-014-0147-5. Epub 2014 Dec 4.

PMID:
25471227

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