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Items: 1 to 20 of 80

1.

Two amino acid substitutions in the haemagglutinin of the 2009 pandemic H1N1 virus decrease direct-contact transmission in guinea pigs.

He L, Jiang K, Wu Q, Duan Z, Xu H, Liu J, Cui Z, Gu M, Wang X, Liu X, Liu X.

J Gen Virol. 2014 Dec;95(Pt 12):2612-7. doi: 10.1099/vir.0.067694-0. Epub 2014 Aug 18.

PMID:
25135885
2.

Key molecular factors in hemagglutinin and PB2 contribute to efficient transmission of the 2009 H1N1 pandemic influenza virus.

Zhang Y, Zhang Q, Gao Y, He X, Kong H, Jiang Y, Guan Y, Xia X, Shu Y, Kawaoka Y, Bu Z, Chen H.

J Virol. 2012 Sep;86(18):9666-74. doi: 10.1128/JVI.00958-12. Epub 2012 Jun 27.

3.

Polymorphisms in the haemagglutinin gene influenced the viral shedding of pandemic 2009 influenza virus in swine.

Lorusso A, Ciacci-Zanella JR, Zanella EL, Pena L, Perez DR, Lager KM, Rajão DS, Loving CL, Kitikoon P, Vincent AL.

J Gen Virol. 2014 Dec;95(Pt 12):2618-26. doi: 10.1099/vir.0.067926-0. Epub 2014 Aug 15.

PMID:
25127710
4.

A single base-pair change in 2009 H1N1 hemagglutinin increases human receptor affinity and leads to efficient airborne viral transmission in ferrets.

Jayaraman A, Pappas C, Raman R, Belser JA, Viswanathan K, Shriver Z, Tumpey TM, Sasisekharan R.

PLoS One. 2011 Mar 2;6(3):e17616. doi: 10.1371/journal.pone.0017616.

5.

A Single-Amino-Acid Substitution at Position 225 in Hemagglutinin Alters the Transmissibility of Eurasian Avian-Like H1N1 Swine Influenza Virus in Guinea Pigs.

Wang Z, Yang H, Chen Y, Tao S, Liu L, Kong H, Ma S, Meng F, Suzuki Y, Qiao C, Chen H.

J Virol. 2017 Oct 13;91(21). pii: e00800-17. doi: 10.1128/JVI.00800-17. Print 2017 Nov 1.

6.

Hemagglutinin-neuraminidase balance confers respiratory-droplet transmissibility of the pandemic H1N1 influenza virus in ferrets.

Yen HL, Liang CH, Wu CY, Forrest HL, Ferguson A, Choy KT, Jones J, Wong DD, Cheung PP, Hsu CH, Li OT, Yuen KM, Chan RW, Poon LL, Chan MC, Nicholls JM, Krauss S, Wong CH, Guan Y, Webster RG, Webby RJ, Peiris M.

Proc Natl Acad Sci U S A. 2011 Aug 23;108(34):14264-9. doi: 10.1073/pnas.1111000108. Epub 2011 Aug 8.

7.

Adaptation of H9N2 AIV in guinea pigs enables efficient transmission by direct contact and inefficient transmission by respiratory droplets.

Sang X, Wang A, Ding J, Kong H, Gao X, Li L, Chai T, Li Y, Zhang K, Wang C, Wan Z, Huang G, Wang T, Feng N, Zheng X, Wang H, Zhao Y, Yang S, Qian J, Hu G, Gao Y, Xia X.

Sci Rep. 2015 Nov 10;5:15928. doi: 10.1038/srep15928.

8.

H5N1 hybrid viruses bearing 2009/H1N1 virus genes transmit in guinea pigs by respiratory droplet.

Zhang Y, Zhang Q, Kong H, Jiang Y, Gao Y, Deng G, Shi J, Tian G, Liu L, Liu J, Guan Y, Bu Z, Chen H.

Science. 2013 Jun 21;340(6139):1459-63. doi: 10.1126/science.1229455. Epub 2013 May 2.

9.

Genetic requirement for hemagglutinin glycosylation and its implications for influenza A H1N1 virus evolution.

Kim JI, Lee I, Park S, Hwang MW, Bae JY, Lee S, Heo J, Park MS, García-Sastre A, Park MS.

J Virol. 2013 Jul;87(13):7539-49. doi: 10.1128/JVI.00373-13. Epub 2013 May 1.

10.

The soft palate is an important site of adaptation for transmissible influenza viruses.

Lakdawala SS, Jayaraman A, Halpin RA, Lamirande EW, Shih AR, Stockwell TB, Lin X, Simenauer A, Hanson CT, Vogel L, Paskel M, Minai M, Moore I, Orandle M, Das SR, Wentworth DE, Sasisekharan R, Subbarao K.

Nature. 2015 Oct 1;526(7571):122-5. doi: 10.1038/nature15379. Epub 2015 Sep 23.

11.

Replication, pathogenesis and transmission of pandemic (H1N1) 2009 virus in non-immune pigs.

Brookes SM, Núñez A, Choudhury B, Matrosovich M, Essen SC, Clifford D, Slomka MJ, Kuntz-Simon G, Garcon F, Nash B, Hanna A, Heegaard PM, Quéguiner S, Chiapponi C, Bublot M, Garcia JM, Gardner R, Foni E, Loeffen W, Larsen L, Van Reeth K, Banks J, Irvine RM, Brown IH.

PLoS One. 2010 Feb 5;5(2):e9068. doi: 10.1371/journal.pone.0009068.

12.

Molecular Characterisation of the Haemagglutinin Glycan-Binding Specificity of Egg-Adapted Vaccine Strains of the Pandemic 2009 H1N1 Swine Influenza A Virus.

Carbone V, Schneider EK, Rockman S, Baker M, Huang JX, Ong C, Cooper MA, Yuriev E, Li J, Velkov T.

Molecules. 2015 Jun 5;20(6):10415-34. doi: 10.3390/molecules200610415.

13.

A two-amino acid change in the hemagglutinin of the 1918 influenza virus abolishes transmission.

Tumpey TM, Maines TR, Van Hoeven N, Glaser L, Solórzano A, Pappas C, Cox NJ, Swayne DE, Palese P, Katz JM, García-Sastre A.

Science. 2007 Feb 2;315(5812):655-9.

14.

Identification of amino acids in HA and PB2 critical for the transmission of H5N1 avian influenza viruses in a mammalian host.

Gao Y, Zhang Y, Shinya K, Deng G, Jiang Y, Li Z, Guan Y, Tian G, Li Y, Shi J, Liu L, Zeng X, Bu Z, Xia X, Kawaoka Y, Chen H.

PLoS Pathog. 2009 Dec;5(12):e1000709. doi: 10.1371/journal.ppat.1000709. Epub 2009 Dec 24.

15.

Changes to the dynamic nature of hemagglutinin and the emergence of the 2009 pandemic H1N1 influenza virus.

Yoon SW, Chen N, Ducatez MF, McBride R, Barman S, Fabrizio TP, Webster RG, Haliloglu T, Paulson JC, Russell CJ, Hertz T, Ben-Tal N, Webby RJ.

Sci Rep. 2015 Aug 13;5:12828. doi: 10.1038/srep12828.

16.

Molecular requirements for a pandemic influenza virus: An acid-stable hemagglutinin protein.

Russier M, Yang G, Rehg JE, Wong SS, Mostafa HH, Fabrizio TP, Barman S, Krauss S, Webster RG, Webby RJ, Russell CJ.

Proc Natl Acad Sci U S A. 2016 Feb 9;113(6):1636-41. doi: 10.1073/pnas.1524384113. Epub 2016 Jan 25.

17.

D225G mutation in hemagglutinin of pandemic influenza H1N1 (2009) virus enhances virulence in mice.

Zheng B, Chan KH, Zhang AJ, Zhou J, Chan CC, Poon VK, Zhang K, Leung VH, Jin DY, Woo PC, Chan JF, To KK, Chen H, Yuen KY.

Exp Biol Med (Maywood). 2010 Aug;235(8):981-8. doi: 10.1258/ebm.2010.010071.

PMID:
20660098
18.

Characterization of an artificial swine-origin influenza virus with the same gene combination as H1N1/2009 virus: a genesis clue of pandemic strain.

Zhao X, Sun Y, Pu J, Fan L, Shi W, Hu Y, Yang J, Xu Q, Wang J, Hou D, Ma G, Liu J.

PLoS One. 2011;6(7):e22091. doi: 10.1371/journal.pone.0022091. Epub 2011 Jul 25.

19.

The T160A hemagglutinin substitution affects not only receptor binding property but also transmissibility of H5N1 clade 2.3.4 avian influenza virus in guinea pigs.

Gu M, Li Q, Gao R, He D, Xu Y, Xu H, Xu L, Wang X, Hu J, Liu X, Hu S, Peng D, Jiao X, Liu X.

Vet Res. 2017 Feb 6;48(1):7. doi: 10.1186/s13567-017-0410-0.

20.

Glycosylation on hemagglutinin affects the virulence and pathogenicity of pandemic H1N1/2009 influenza A virus in mice.

Zhang Y, Zhu J, Li Y, Bradley KC, Cao J, Chen H, Jin M, Zhou H.

PLoS One. 2013 Apr 24;8(4):e61397. doi: 10.1371/journal.pone.0061397. Print 2013.

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