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Items: 1 to 20 of 109

1.

Brief report: complement C5a promotes human embryonic stem cell pluripotency in the absence of FGF2.

Hawksworth OA, Coulthard LG, Taylor SM, Wolvetang EJ, Woodruff TM.

Stem Cells. 2014 Dec;32(12):3278-84. doi: 10.1002/stem.1801.

2.

Receptors for complement C5a. The importance of C5aR and the enigmatic role of C5L2.

Lee H, Whitfeld PL, Mackay CR.

Immunol Cell Biol. 2008 Feb;86(2):153-60. doi: 10.1038/sj.icb.7100166. Epub 2008 Jan 29. Review.

PMID:
18227853
3.

Complement C5aR1 Signaling Promotes Polarization and Proliferation of Embryonic Neural Progenitor Cells through PKCζ.

Coulthard LG, Hawksworth OA, Li R, Balachandran A, Lee JD, Sepehrband F, Kurniawan N, Jeanes A, Simmons DG, Wolvetang E, Woodruff TM.

J Neurosci. 2017 May 31;37(22):5395-5407. doi: 10.1523/JNEUROSCI.0525-17.2017. Epub 2017 Apr 28.

4.

The interaction between C5a and both C5aR and C5L2 receptors is required for production of G-CSF during acute inflammation.

Bosmann M, Haggadone MD, Zetoune FS, Sarma JV, Ward PA.

Eur J Immunol. 2013 Jul;43(7):1907-13. doi: 10.1002/eji.201243075. Epub 2013 May 13.

5.

The harmful role of c5a on innate immunity in sepsis.

Ward PA.

J Innate Immun. 2010;2(5):439-45. doi: 10.1159/000317194. Epub 2010 Jun 26. Review.

6.

Functions of C5a receptors.

Ward PA.

J Mol Med (Berl). 2009 Apr;87(4):375-8. doi: 10.1007/s00109-009-0442-7. Epub 2009 Feb 3. Review.

7.

Role of C5 activation products in sepsis.

Ward PA.

ScientificWorldJournal. 2010 Dec 14;10:2395-402. doi: 10.1100/tsw.2010.216. Review.

8.

Absence of signaling into CD4⁺ cells via C3aR and C5aR enables autoinductive TGF-β1 signaling and induction of Foxp3⁺ regulatory T cells.

Strainic MG, Shevach EM, An F, Lin F, Medof ME.

Nat Immunol. 2013 Feb;14(2):162-71. doi: 10.1038/ni.2499. Epub 2012 Dec 23.

9.

Human colonic epithelial cells detect and respond to C5a via apically expressed C5aR through the ERK pathway.

Cao Q, McIsaac SM, Stadnyk AW.

Am J Physiol Cell Physiol. 2012 Jun 15;302(12):C1731-40. doi: 10.1152/ajpcell.00213.2011. Epub 2012 Apr 11.

10.

Expression of a functional C5a receptor in regenerating hepatocytes and its involvement in a proliferative signaling pathway in rat.

Daveau M, Benard M, Scotte M, Schouft MT, Hiron M, Francois A, Salier JP, Fontaine M.

J Immunol. 2004 Sep 1;173(5):3418-24.

11.

C5a regulates NKT and NK cell functions in sepsis.

Fusakio ME, Mohammed JP, Laumonnier Y, Hoebe K, Köhl J, Mattner J.

J Immunol. 2011 Dec 1;187(11):5805-12. doi: 10.4049/jimmunol.1100338. Epub 2011 Nov 4.

12.

Role of C5a-C5aR interaction in sepsis.

Guo RF, Riedemann NC, Ward PA.

Shock. 2004 Jan;21(1):1-7. Review.

PMID:
14676676
13.

TLR activation enhances C5a-induced pro-inflammatory responses by negatively modulating the second C5a receptor, C5L2.

Raby AC, Holst B, Davies J, Colmont C, Laumonnier Y, Coles B, Shah S, Hall J, Topley N, Köhl J, Morgan BP, Labéta MO.

Eur J Immunol. 2011 Sep;41(9):2741-52. doi: 10.1002/eji.201041350. Epub 2011 Aug 4.

14.

C5aR and C5L2 act in concert to balance immunometabolism in adipose tissue.

Poursharifi P, Lapointe M, Fisette A, Lu H, Roy C, Munkonda MN, Fairlie DP, Cianflone K.

Mol Cell Endocrinol. 2014 Jan 25;382(1):325-333. doi: 10.1016/j.mce.2013.10.019. Epub 2013 Oct 25.

PMID:
24397921
15.

C5a initiates the inflammatory cascade in immune complex peritonitis.

Godau J, Heller T, Hawlisch H, Trappe M, Howells E, Best J, Zwirner J, Verbeek JS, Hogarth PM, Gerard C, Van Rooijen N, Klos A, Gessner JE, Köhl J.

J Immunol. 2004 Sep 1;173(5):3437-45.

16.

C5L2, a nonsignaling C5A binding protein.

Okinaga S, Slattery D, Humbles A, Zsengeller Z, Morteau O, Kinrade MB, Brodbeck RM, Krause JE, Choe HR, Gerard NP, Gerard C.

Biochemistry. 2003 Aug 12;42(31):9406-15.

PMID:
12899627
17.

Anaphylatoxin C5a-induced toll-like receptor 4 signaling in bovine neutrophils.

Stevens MG, Van Poucke M, Peelman LJ, Rainard P, De Spiegeleer B, Rogiers C, Van de Walle GR, Duchateau L, Burvenich C.

J Dairy Sci. 2011 Jan;94(1):152-64. doi: 10.3168/jds.2010-3358.

PMID:
21183027
18.

Development of FGF2-dependent pluripotent stem cells showing naive state characteristics from murine preimplantation inner cell mass.

Ozawa M, Kawakami E, Sakamoto R, Shibasaki T, Goto A, Yoshida N.

Stem Cell Res. 2014 Jul;13(1):75-87. doi: 10.1016/j.scr.2014.04.012. Epub 2014 Apr 26.

20.

Inhibiting the C5-C5a receptor axis.

Woodruff TM, Nandakumar KS, Tedesco F.

Mol Immunol. 2011 Aug;48(14):1631-42. doi: 10.1016/j.molimm.2011.04.014. Epub 2011 May 6. Review.

PMID:
21549429

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