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Items: 1 to 20 of 87

1.

Drug elucidation: invertebrate genetics sheds new light on the molecular targets of CNS drugs.

Dwyer DS, Aamodt E, Cohen B, Buttner EA.

Front Pharmacol. 2014 Jul 28;5:177. doi: 10.3389/fphar.2014.00177. eCollection 2014. Review.

3.

[Development of antituberculous drugs: current status and future prospects].

Tomioka H, Namba K.

Kekkaku. 2006 Dec;81(12):753-74. Review. Japanese.

PMID:
17240921
4.

[Antipsychotics in bipolar disorders].

Vacheron-Trystram MN, Braitman A, Cheref S, Auffray L.

Encephale. 2004 Sep-Oct;30(5):417-24. Review. French.

PMID:
15627046
5.

Receptorome screening for CNS drug discovery.

Vortherms TA, Roth BL.

IDrugs. 2005 Jun;8(6):491-6. Review.

PMID:
15906196
6.

Caenorhabditis elegans as a Model to Study the Molecular and Genetic Mechanisms of Drug Addiction.

Engleman EA, Katner SN, Neal-Beliveau BS.

Prog Mol Biol Transl Sci. 2016;137:229-52. doi: 10.1016/bs.pmbts.2015.10.019. Epub 2015 Nov 24. Review.

7.

[Clinically relevant drug interactions with new generation antidepressants and antipsychotics].

Eckert A.

Ther Umsch. 2009 Jun;66(6):485-92. doi: 10.1024/0040-5930.66.6.485. Review. German.

PMID:
19496045
8.

Pharmacological treatment of schizophrenia: a critical review of the pharmacology and clinical effects of current and future therapeutic agents.

Miyamoto S, Miyake N, Jarskog LF, Fleischhacker WW, Lieberman JA.

Mol Psychiatry. 2012 Dec;17(12):1206-27. doi: 10.1038/mp.2012.47. Epub 2012 May 15. Review.

PMID:
22584864
9.

Summary of the comparative effectiveness review on off-label use of atypical antipsychotics.

Maher AR, Theodore G.

J Manag Care Pharm. 2012 Jun;18(5 Suppl B):S1-20. Review.

PMID:
22784311
10.

Antipsychotic drugs activate the C. elegans akt pathway via the DAF-2 insulin/IGF-1 receptor.

Weeks KR, Dwyer DS, Aamodt EJ.

ACS Chem Neurosci. 2010 Jun 16;1(6):463-73. doi: 10.1021/cn100010p. Epub 2010 Mar 25.

11.

Distinct molecular targets including SLO-1 and gap junctions are engaged across a continuum of ethanol concentrations in Caenorhabditis elegans.

Dillon J, Andrianakis I, Mould R, Ient B, Liu W, James C, O'Connor V, Holden-Dye L.

FASEB J. 2013 Oct;27(10):4266-78. doi: 10.1096/fj.11-189340. Epub 2013 Jul 23.

12.

Cancer Drug Development: New Targets for Cancer Treatment.

Curt GA.

Oncologist. 1996;1(3):II-III.

PMID:
10387987
13.
14.

Caenorhabditis elegans: A Model System for Anti-Cancer Drug Discovery and Therapeutic Target Identification.

Kobet RA, Pan X, Zhang B, Pak SC, Asch AS, Lee MH.

Biomol Ther (Seoul). 2014 Sep;22(5):371-83. doi: 10.4062/biomolther.2014.084. Epub 2014 Sep 30. Review.

15.

Discovery of anthelmintic drug targets and drugs using chokepoints in nematode metabolic pathways.

Taylor CM, Wang Q, Rosa BA, Huang SC, Powell K, Schedl T, Pearce EJ, Abubucker S, Mitreva M.

PLoS Pathog. 2013;9(8):e1003505. doi: 10.1371/journal.ppat.1003505. Epub 2013 Aug 1.

16.

Invertebrate models of drug abuse.

Wolf FW, Heberlein U.

J Neurobiol. 2003 Jan;54(1):161-78. Review.

17.

New approaches to drug discovery and development: a mechanism-based approach to pharmaceutical research and its application to BNP7787, a novel chemoprotective agent.

Hausheer FH, Kochat H, Parker AR, Ding D, Yao S, Hamilton SE, Petluru PN, Leverett BD, Bain SH, Saxe JD.

Cancer Chemother Pharmacol. 2003 Jul;52 Suppl 1:S3-15. Epub 2003 Jun 18. Review.

PMID:
12819940
18.

Identification of potential therapeutic drugs for huntington's disease using Caenorhabditis elegans.

Voisine C, Varma H, Walker N, Bates EA, Stockwell BR, Hart AC.

PLoS One. 2007 Jun 6;2(6):e504.

19.

Social feeding in Caenorhabditis elegans is modulated by antipsychotic drugs and calmodulin and may serve as a protophenotype for asociality.

Dwyer DS, Awatramani P, Thakur R, Seeni R, Aamodt EJ.

Neuropharmacology. 2015 May;92:56-62. doi: 10.1016/j.neuropharm.2014.12.027. Epub 2015 Jan 7.

PMID:
25576370
20.

The year's new drugs & biologics - 2008.

Graul AI, Revel L, Barrionuevo M, Cruces E, Rosa E, Verges C, Lupone B, Diaz N, Castaner R.

Drug News Perspect. 2009 Jan-Feb;22(1):7-29. doi: 10.1358/dnp.2009.22.1.1303754.

PMID:
19209296

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