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Items: 1 to 20 of 100

1.

Tolerance-like innate immunity and spleen injury: a novel discovery via the weekly administrations and consecutive injections of PEGylated emulsions.

Wang L, Wang C, Jiao J, Su Y, Cheng X, Huang Z, Liu X, Deng Y.

Int J Nanomedicine. 2014 Aug 4;9:3645-57. doi: 10.2147/IJN.S66318. eCollection 2014.

2.

A noticeable phenomenon: thiol terminal PEG enhances the immunogenicity of PEGylated emulsions injected intravenously or subcutaneously into rats.

Wang C, Cheng X, Sui Y, Luo X, Jiang G, Wang Y, Huang Z, She Z, Deng Y.

Eur J Pharm Biopharm. 2013 Nov;85(3 Pt A):744-51. doi: 10.1016/j.ejpb.2013.10.002. Epub 2013 Oct 12.

PMID:
24129310
3.

Accelerated blood clearance phenomenon upon cross-administration of PEGylated nanocarriers in beagle dogs.

Wang C, Cheng X, Su Y, Pei Y, Song Y, Jiao J, Huang Z, Ma Y, Dong Y, Yao Y, Fan J, Ta H, Liu X, Xu H, Deng Y.

Int J Nanomedicine. 2015 May 14;10:3533-45. doi: 10.2147/IJN.S82481. eCollection 2015.

4.

Accelerated blood clearance and altered biodistribution of repeated injections of sterically stabilized liposomes.

Dams ET, Laverman P, Oyen WJ, Storm G, Scherphof GL, van Der Meer JW, Corstens FH, Boerman OC.

J Pharmacol Exp Ther. 2000 Mar;292(3):1071-9.

5.
6.

Accelerated clearance of PEGylated liposomes in rats after repeated injections.

Ishida T, Maeda R, Ichihara M, Irimura K, Kiwada H.

J Control Release. 2003 Feb 14;88(1):35-42.

PMID:
12586501
7.

Accelerated blood clearance of PEGylated liposomes upon repeated injections: effect of doxorubicin-encapsulation and high-dose first injection.

Ishida T, Atobe K, Wang X, Kiwada H.

J Control Release. 2006 Oct 27;115(3):251-8. Epub 2006 Sep 3.

PMID:
17045355
8.

PEGylated liposomes elicit an anti-PEG IgM response in a T cell-independent manner.

Ishida T, Wang X, Shimizu T, Nawata K, Kiwada H.

J Control Release. 2007 Oct 8;122(3):349-55. Epub 2007 May 21.

PMID:
17610982
9.

Spleen plays an important role in the induction of accelerated blood clearance of PEGylated liposomes.

Ishida T, Ichihara M, Wang X, Kiwada H.

J Control Release. 2006 Oct 27;115(3):243-50. Epub 2006 Aug 7.

PMID:
17011060
10.

[Nonspecific non-reactivity in mice induced by joint administration of Newcastle disease virus and cyclophosphamide].

Kondrat'eva TK, Mikheeva NV, Mamontova TV, Kognovitskaia AI, Fontalin LN, Orlova TG.

Vopr Virusol. 1990 Nov-Dec;35(6):494-7. Russian.

PMID:
2082554
11.

Intravenous administration of polyethylene glycol-coated (PEGylated) proteins and PEGylated adenovirus elicits an anti-PEG immunoglobulin M response.

Shimizu T, Ichihara M, Yoshioka Y, Ishida T, Nakagawa S, Kiwada H.

Biol Pharm Bull. 2012;35(8):1336-42.

12.

Long-circulating emulsions (oil-in-water) as carriers for lipophilic drugs.

Liu F, Liu D.

Pharm Res. 1995 Jul;12(7):1060-4.

PMID:
7494803
13.

Acute cadmium administration to rats exerts both immunosuppressive and proinflammatory effects in spleen.

Demenesku J, Mirkov I, Ninkov M, Popov Aleksandrov A, Zolotarevski L, Kataranovski D, Kataranovski M.

Toxicology. 2014 Dec 4;326:96-108. doi: 10.1016/j.tox.2014.10.012. Epub 2014 Oct 27.

PMID:
25446329
14.

Use of polyglycerol (PG), instead of polyethylene glycol (PEG), prevents induction of the accelerated blood clearance phenomenon against long-circulating liposomes upon repeated administration.

Abu Lila AS, Nawata K, Shimizu T, Ishida T, Kiwada H.

Int J Pharm. 2013 Nov 1;456(1):235-42. doi: 10.1016/j.ijpharm.2013.07.059. Epub 2013 Aug 5.

PMID:
23928149
16.

Preclinical and clinical evidence for disappearance of long-circulating characteristics of polyethylene glycol liposomes at low lipid dose.

Laverman P, Brouwers AH, Dams ET, Oyen WJ, Storm G, van Rooijen N, Corstens FH, Boerman OC.

J Pharmacol Exp Ther. 2000 Jun;293(3):996-1001.

17.

Injection of PEGylated liposomes in rats elicits PEG-specific IgM, which is responsible for rapid elimination of a second dose of PEGylated liposomes.

Ishida T, Ichihara M, Wang X, Yamamoto K, Kimura J, Majima E, Kiwada H.

J Control Release. 2006 May 1;112(1):15-25. Epub 2006 Mar 3.

PMID:
16515818
18.
19.

Anti-PEG IgM and complement system are required for the association of second doses of PEGylated liposomes with splenic marginal zone B cells.

Shimizu T, Mima Y, Hashimoto Y, Ukawa M, Ando H, Kiwada H, Ishida T.

Immunobiology. 2015 Oct;220(10):1151-60. doi: 10.1016/j.imbio.2015.06.005. Epub 2015 Jun 6.

PMID:
26095176
20.

Accelerated drug release and clearance of PEGylated epirubicin liposomes following repeated injections: a new challenge for sequential low-dose chemotherapy.

Yang Q, Ma Y, Zhao Y, She Z, Wang L, Li J, Wang C, Deng Y.

Int J Nanomedicine. 2013;8:1257-68. doi: 10.2147/IJN.S41701. Epub 2013 Mar 28.

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