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Items: 1 to 20 of 61

1.

Active components with inhibitory activities on IFN-γ/STAT1 and IL-6/STAT3 signaling pathways from Caulis Trachelospermi.

Liu XT, Wang ZX, Yang Y, Wang L, Sun RF, Zhao YM, Yu NJ.

Molecules. 2014 Aug 5;19(8):11560-71. doi: 10.3390/molecules190811560.

2.

Novel secolignans from Peperomia dindygulensis and their inhibitory activities on JAK-STAT signaling pathways.

Sun RF, Zhu CC, Yang Y, Yu NJ.

Fitoterapia. 2017 Oct;122:80-84. doi: 10.1016/j.fitote.2017.08.018. Epub 2017 Aug 30.

PMID:
28859930
3.

Dendritic cells from Crohn's disease patients show aberrant STAT1 and STAT3 signaling.

Nieminen JK, Niemi M, Sipponen T, Salo HM, Klemetti P, Färkkilä M, Vakkila J, Vaarala O.

PLoS One. 2013 Aug 7;8(8):e70738. doi: 10.1371/journal.pone.0070738. eCollection 2013.

4.

Interferon-gamma-induced dephosphorylation of STAT3 and apoptosis are dependent on the mTOR pathway.

Fang P, Hwa V, Rosenfeld RG.

Exp Cell Res. 2006 May 1;312(8):1229-39. Epub 2006 Jan 19.

PMID:
16427044
5.

IL-6, but not IFN-gamma, triggers apoptosis and inhibits in vivo growth of human malignant T cells on STAT3 silencing.

Regis G, Icardi L, Conti L, Chiarle R, Piva R, Giovarelli M, Poli V, Novelli F.

Leukemia. 2009 Nov;23(11):2102-8. doi: 10.1038/leu.2009.139. Epub 2009 Jul 23.

PMID:
19626047
6.

"Activated" STAT proteins: a paradoxical consequence of inhibited JAK-STAT signaling in cytomegalovirus-infected cells.

Trilling M, Le VT, Rashidi-Alavijeh J, Katschinski B, Scheller J, Rose-John S, Androsiac GE, Jonjic S, Poli V, Pfeffer K, Hengel H.

J Immunol. 2014 Jan 1;192(1):447-58. doi: 10.4049/jimmunol.1203516. Epub 2013 Dec 6.

8.

Elucidating the crosstalk mechanism between IFN-gamma and IL-6 via mathematical modelling.

Qi YF, Huang YX, Wang HY, Zhang Y, Bao YL, Sun LG, Wu Y, Yu CL, Song ZB, Zheng LH, Sun Y, Wang GN, Li YX.

BMC Bioinformatics. 2013 Feb 6;14:41. doi: 10.1186/1471-2105-14-41.

9.

Antiproliferative mechanisms of a transcription factor decoy targeting signal transducer and activator of transcription (STAT) 3: the role of STAT1.

Lui VW, Boehm AL, Koppikar P, Leeman RJ, Johnson D, Ogagan M, Childs E, Freilino M, Grandis JR.

Mol Pharmacol. 2007 May;71(5):1435-43. Epub 2007 Feb 26.

10.

Podoplanin expression in wound and hyperproliferative psoriatic epidermis: regulation by TGF-β and STAT-3 activating cytokines, IFN-γ, IL-6, and IL-22.

Honma M, Minami-Hori M, Takahashi H, Iizuka H.

J Dermatol Sci. 2012 Feb;65(2):134-40. doi: 10.1016/j.jdermsci.2011.11.011. Epub 2011 Dec 8.

PMID:
22189341
11.
12.

Angoline: a selective IL-6/STAT3 signaling pathway inhibitor isolated from Zanthoxylum nitidum.

Liu J, Zhang Q, Ye Y, Li W, Qiu J, Liu J, Zhan R, Chen W, Yu Q.

Phytomedicine. 2014 Jul-Aug;21(8-9):1088-91. doi: 10.1016/j.phymed.2014.04.001. Epub 2014 May 24.

PMID:
24863036
13.

Brahma-related gene 1-dependent STAT3 recruitment at IL-6-inducible genes.

Ni Z, Bremner R.

J Immunol. 2007 Jan 1;178(1):345-51.

14.

Arctigenin inhibits lipopolysaccharide-induced iNOS expression in RAW264.7 cells through suppressing JAK-STAT signal pathway.

Kou X, Qi S, Dai W, Luo L, Yin Z.

Int Immunopharmacol. 2011 Aug;11(8):1095-102. doi: 10.1016/j.intimp.2011.03.005. Epub 2011 Mar 21.

PMID:
21426947
15.

Induction of an interferon-gamma Stat3 response in nerve cells by pre-treatment with gp130 cytokines.

Kaur N, Kim IJ, Higgins D, Halvorsen SW.

J Neurochem. 2003 Oct;87(2):437-47.

17.

Both STAT1 and STAT3 are favourable prognostic determinants in colorectal carcinoma.

Gordziel C, Bratsch J, Moriggl R, Knösel T, Friedrich K.

Br J Cancer. 2013 Jul 9;109(1):138-46. doi: 10.1038/bjc.2013.274. Epub 2013 Jun 11.

18.

JAK and STAT proteins are expressed and activated by IFN-gamma in rat pancreatic acinar cells.

Gallmeier E, Schäfer C, Moubarak P, Tietz A, Plössl I, Huss R, Göke B, Wagner AC.

J Cell Physiol. 2005 Apr;203(1):209-16.

PMID:
15493010
19.

Janus kinase-signal transducer and activator of transcription mediates phosphatidic acid-induced interleukin (IL)-1beta and IL-6 production.

Lee C, Lim HK, Sakong J, Lee YS, Kim JR, Baek SH.

Mol Pharmacol. 2006 Mar;69(3):1041-7. Epub 2005 Dec 14.

20.

STAT1 and STAT3 phosphorylation by porins are independent of JAKs but are dependent on MAPK pathway and plays a role in U937 cells production of interleukin-6.

Galdiero M, Vitiello M, D'Isanto M, Raieta K, Galdiero E.

Cytokine. 2006 Dec;36(5-6):218-28. Epub 2007 Jan 26.

PMID:
17258468

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