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Items: 1 to 20 of 157


Identification of a novel AMPK-PEA15 axis in the anoikis-resistant growth of mammary cells.

Hindupur SK, Balaji SA, Saxena M, Pandey S, Sravan GS, Heda N, Kumar MV, Mukherjee G, Dey D, Rangarajan A.

Breast Cancer Res. 2014 Aug 6;16(4):420. doi: 10.1186/s13058-014-0420-z.


Loss of anchorage primarily induces non-apoptotic cell death in a human mammary epithelial cell line under atypical focal adhesion kinase signaling.

Ishikawa F, Ushida K, Mori K, Shibanuma M.

Cell Death Dis. 2015 Jan 22;6:e1619. doi: 10.1038/cddis.2014.583.


Hypoxia suppression of Bim and Bmf blocks anoikis and luminal clearing during mammary morphogenesis.

Whelan KA, Caldwell SA, Shahriari KS, Jackson SR, Franchetti LD, Johannes GJ, Reginato MJ.

Mol Biol Cell. 2010 Nov 15;21(22):3829-37. doi: 10.1091/mbc.E10-04-0353. Epub 2010 Sep 22.


Deletion of PTEN promotes tumorigenic signaling, resistance to anoikis, and altered response to chemotherapeutic agents in human mammary epithelial cells.

Vitolo MI, Weiss MB, Szmacinski M, Tahir K, Waldman T, Park BH, Martin SS, Weber DJ, Bachman KE.

Cancer Res. 2009 Nov 1;69(21):8275-83. doi: 10.1158/0008-5472.CAN-09-1067. Epub 2009 Oct 20.


Blockade of CCN6 (WISP3) activates growth factor-independent survival and resistance to anoikis in human mammary epithelial cells.

Huang W, Gonzalez ME, Toy KA, Banerjee M, Kleer CG.

Cancer Res. 2010 Apr 15;70(8):3340-50. doi: 10.1158/0008-5472.CAN-09-4225.


TDAG51 is an ERK signaling target that opposes ERK-mediated HME16C mammary epithelial cell transformation.

Oberst MD, Beberman SJ, Zhao L, Yin JJ, Ward Y, Kelly K.

BMC Cancer. 2008 Jul 2;8:189. doi: 10.1186/1471-2407-8-189.


A MYC-Driven Change in Mitochondrial Dynamics Limits YAP/TAZ Function in Mammary Epithelial Cells and Breast Cancer.

von Eyss B, Jaenicke LA, Kortlever RM, Royla N, Wiese KE, Letschert S, McDuffus LA, Sauer M, Rosenwald A, Evan GI, Kempa S, Eilers M.

Cancer Cell. 2015 Dec 14;28(6):743-757. doi: 10.1016/j.ccell.2015.10.013.


Mesenchymal stem cells promote mammosphere formation and decrease E-cadherin in normal and malignant breast cells.

Klopp AH, Lacerda L, Gupta A, Debeb BG, Solley T, Li L, Spaeth E, Xu W, Zhang X, Lewis MT, Reuben JM, Krishnamurthy S, Ferrari M, Gaspar R, Buchholz TA, Cristofanilli M, Marini F, Andreeff M, Woodward WA.

PLoS One. 2010 Aug 16;5(8):e12180. doi: 10.1371/journal.pone.0012180.


ErbB2 requires integrin alpha5 for anoikis resistance via Src regulation of receptor activity in human mammary epithelial cells.

Haenssen KK, Caldwell SA, Shahriari KS, Jackson SR, Whelan KA, Klein-Szanto AJ, Reginato MJ.

J Cell Sci. 2010 Apr 15;123(Pt 8):1373-82. doi: 10.1242/jcs.050906. Epub 2010 Mar 23.


Activation of AMP-activated protein kinase (AMPK) mediates plumbagin-induced apoptosis and growth inhibition in cultured human colon cancer cells.

Chen MB, Zhang Y, Wei MX, Shen W, Wu XY, Yao C, Lu PH.

Cell Signal. 2013 Oct;25(10):1993-2002. doi: 10.1016/j.cellsig.2013.05.026. Epub 2013 May 25.


Antitumor effect of E1A in ovarian cancer by cytoplasmic sequestration of activated ERK by PEA15.

Bartholomeusz C, Itamochi H, Nitta M, Saya H, Ginsberg MH, Ueno NT.

Oncogene. 2006 Jan 5;25(1):79-90.


Anchorage-independent phosphorylation of p130(Cas) protects lung adenocarcinoma cells from anoikis.

Wei L, Yang Y, Zhang X, Yu Q.

J Cell Biochem. 2002;87(4):439-49.


Protein tyrosine kinase 6 protects cells from anoikis by directly phosphorylating focal adhesion kinase and activating AKT.

Zheng Y, Gierut J, Wang Z, Miao J, Asara JM, Tyner AL.

Oncogene. 2013 Sep 5;32(36):4304-12. doi: 10.1038/onc.2012.427. Epub 2012 Oct 1.


AMP-Activated Protein Kinase α 2 Isoform Suppression in Primary Breast Cancer Alters AMPK Growth Control and Apoptotic Signaling.

Fox MM, Phoenix KN, Kopsiaftis SG, Claffey KP.

Genes Cancer. 2013 Jan;4(1-2):3-14. doi: 10.1177/1947601913486346.


Overexpression of fatty acid synthase gene activates HER1/HER2 tyrosine kinase receptors in human breast epithelial cells.

Vazquez-Martin A, Colomer R, Brunet J, Lupu R, Menendez JA.

Cell Prolif. 2008 Feb;41(1):59-85. doi: 10.1111/j.1365-2184.2007.00498.x.


Calcium-Oxidant Signaling Network Regulates AMP-activated Protein Kinase (AMPK) Activation upon Matrix Deprivation.

Sundararaman A, Amirtham U, Rangarajan A.

J Biol Chem. 2016 Jul 8;291(28):14410-29. doi: 10.1074/jbc.M116.731257. Epub 2016 May 11.


The protein phosphatase 4 - PEA15 axis regulates the survival of breast cancer cells.

Mohammed HN, Pickard MR, Mourtada-Maarabouni M.

Cell Signal. 2016 Sep;28(9):1389-400. doi: 10.1016/j.cellsig.2016.06.011. Epub 2016 Jun 15.


Silencing of TMS1/ASC promotes resistance to anoikis in breast epithelial cells.

Parsons MJ, Patel P, Brat DJ, Colbert L, Vertino PM.

Cancer Res. 2009 Mar 1;69(5):1706-11. doi: 10.1158/0008-5472.CAN-08-2351. Epub 2009 Feb 17.

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