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Items: 1 to 20 of 69

1.

Sphingomyelin Synthase 1 Regulates Neuro-2a Cell Proliferation and Cell Cycle Progression Through Modulation of p27 Expression and Akt Signaling.

Wesley UV, Hatcher JF, Dempsey RJ.

Mol Neurobiol. 2015;51(3):1530-41. doi: 10.1007/s12035-014-8829-z. Epub 2014 Aug 2.

2.

Inhibition of sphingomyelin synthase (SMS) affects intracellular sphingomyelin accumulation and plasma membrane lipid organization.

Li Z, Hailemariam TK, Zhou H, Li Y, Duckworth DC, Peake DA, Zhang Y, Kuo MS, Cao G, Jiang XC.

Biochim Biophys Acta. 2007 Sep;1771(9):1186-94. Epub 2007 Jun 6.

3.

ErbB2/neu kinase modulates cellular p27(Kip1) and cyclin D1 through multiple signaling pathways.

Lenferink AE, Busse D, Flanagan WM, Yakes FM, Arteaga CL.

Cancer Res. 2001 Sep 1;61(17):6583-91.

4.

Impaired TCR signaling through dysfunction of lipid rafts in sphingomyelin synthase 1 (SMS1)-knockdown T cells.

Jin ZX, Huang CR, Dong L, Goda S, Kawanami T, Sawaki T, Sakai T, Tong XP, Masaki Y, Fukushima T, Tanaka M, Mimori T, Tojo H, Bloom ET, Okazaki T, Umehara H.

Int Immunol. 2008 Nov;20(11):1427-37. doi: 10.1093/intimm/dxn100. Epub 2008 Sep 26.

PMID:
18820264
5.

PDK1 regulates cell proliferation and cell cycle progression through control of cyclin D1 and p27Kip1 expression.

Nakamura K, Sakaue H, Nishizawa A, Matsuki Y, Gomi H, Watanabe E, Hiramatsua R, Tamamori-Adachi M, Kitajima S, Noda T, Ogawa W, Kasuga M.

J Biol Chem. 2008 Jun 20;283(25):17702-11. doi: 10.1074/jbc.M802589200. Epub 2008 Apr 22.

6.

Caspase-mediated inhibition of sphingomyelin synthesis is involved in FasL-triggered cell death.

Lafont E, Milhas D, Carpentier S, Garcia V, Jin ZX, Umehara H, Okazaki T, Schulze-Osthoff K, Levade T, Benoist H, Ségui B.

Cell Death Differ. 2010 Apr;17(4):642-54. doi: 10.1038/cdd.2009.130. Epub 2009 Sep 25.

7.

Development of a quantitative biochemical and cellular sphingomyelin synthase assay using mass spectrometry.

Chen Y, Yurek DA, Yu L, Wang H, Ehsani ME, Qian YW, Konrad RJ, Jiang XC, Kuo MS, Cao G, Wang J.

Anal Biochem. 2013 Jul 1;438(1):61-6. doi: 10.1016/j.ab.2013.03.016. Epub 2013 Mar 25.

PMID:
23535273
8.

Both sphingomyelin synthases SMS1 and SMS2 are required for sphingomyelin homeostasis and growth in human HeLa cells.

Tafesse FG, Huitema K, Hermansson M, van der Poel S, van den Dikkenberg J, Uphoff A, Somerharju P, Holthuis JC.

J Biol Chem. 2007 Jun 15;282(24):17537-47. Epub 2007 Apr 22.

9.

Adenovirus-mediated overexpression of sphingomyelin synthases 1 and 2 increases the atherogenic potential in mice.

Dong J, Liu J, Lou B, Li Z, Ye X, Wu M, Jiang XC.

J Lipid Res. 2006 Jun;47(6):1307-14. Epub 2006 Feb 28.

10.

Knockdown of protein tyrosine phosphatase SHP-1 inhibits G1/S progression in prostate cancer cells through the regulation of components of the cell-cycle machinery.

Rodríguez-Ubreva FJ, Cariaga-Martinez AE, Cortés MA, Romero-De Pablos M, Ropero S, López-Ruiz P, Colás B.

Oncogene. 2010 Jan 21;29(3):345-55. doi: 10.1038/onc.2009.329. Epub 2009 Oct 19.

PMID:
19838216
11.
12.

Deficiency of sphingomyelin synthase-1 but not sphingomyelin synthase-2 causes hearing impairments in mice.

Lu MH, Takemoto M, Watanabe K, Luo H, Nishimura M, Yano M, Tomimoto H, Okazaki T, Oike Y, Song WJ.

J Physiol. 2012 Aug 15;590(16):4029-44. doi: 10.1113/jphysiol.2012.235846. Epub 2012 May 28.

13.
14.

Role of PI3K and AKT specific isoforms in ovarian cancer cell migration, invasion and proliferation through the p70S6K1 pathway.

Meng Q, Xia C, Fang J, Rojanasakul Y, Jiang BH.

Cell Signal. 2006 Dec;18(12):2262-71. Epub 2006 Jun 2.

PMID:
16839745
15.

PD-1 inhibits T cell proliferation by upregulating p27 and p15 and suppressing Cdc25A.

Patsoukis N, Sari D, Boussiotis VA.

Cell Cycle. 2012 Dec 1;11(23):4305-9. doi: 10.4161/cc.22135. Epub 2012 Oct 3.

16.

Expression cloning of a human cDNA restoring sphingomyelin synthesis and cell growth in sphingomyelin synthase-defective lymphoid cells.

Yamaoka S, Miyaji M, Kitano T, Umehara H, Okazaki T.

J Biol Chem. 2004 Apr 30;279(18):18688-93. Epub 2004 Feb 19.

17.

Integrin-dependent signal transduction regulating cyclin D1 expression and G1 phase cell cycle progression.

Walker JL, Assoian RK.

Cancer Metastasis Rev. 2005 Sep;24(3):383-93. Review.

PMID:
16258726
18.

Impact of sphingomyelin synthase 1 deficiency on sphingolipid metabolism and atherosclerosis in mice.

Li Z, Fan Y, Liu J, Li Y, Huan C, Bui HH, Kuo MS, Park TS, Cao G, Jiang XC.

Arterioscler Thromb Vasc Biol. 2012 Jul;32(7):1577-84. doi: 10.1161/ATVBAHA.112.251538. Epub 2012 May 10.

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