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Items: 1 to 20 of 94

1.

Common dysregulation network in the human prefrontal cortex underlies two neurodegenerative diseases.

Narayanan M, Huynh JL, Wang K, Yang X, Yoo S, McElwee J, Zhang B, Zhang C, Lamb JR, Xie T, Suver C, Molony C, Melquist S, Johnson AD, Fan G, Stone DJ, Schadt EE, Casaccia P, Emilsson V, Zhu J.

Mol Syst Biol. 2014 Jul 30;10:743. doi: 10.15252/msb.20145304.

2.

The Role of H3K4me3 in Transcriptional Regulation Is Altered in Huntington's Disease.

Dong X, Tsuji J, Labadorf A, Roussos P, Chen JF, Myers RH, Akbarian S, Weng Z.

PLoS One. 2015 Dec 4;10(12):e0144398. doi: 10.1371/journal.pone.0144398. eCollection 2015.

3.

5-Hydroxymethylation-associated epigenetic modifiers of Alzheimer's disease modulate Tau-induced neurotoxicity.

Bernstein AI, Lin Y, Street RC, Lin L, Dai Q, Yu L, Bao H, Gearing M, Lah JJ, Nelson PT, He C, Levey AI, Mullé JG, Duan R, Jin P.

Hum Mol Genet. 2016 Jun 15;25(12):2437-2450. Epub 2016 Apr 9.

4.

Differentially co-expressed genes in postmortem prefrontal cortex of individuals with alcohol use disorders: influence on alcohol metabolism-related pathways.

Zhang H, Wang F, Xu H, Liu Y, Liu J, Zhao H, Gelernter J.

Hum Genet. 2014 Nov;133(11):1383-94. doi: 10.1007/s00439-014-1473-x. Epub 2014 Jul 30.

5.

MicroRNAs located in the Hox gene clusters are implicated in huntington's disease pathogenesis.

Hoss AG, Kartha VK, Dong X, Latourelle JC, Dumitriu A, Hadzi TC, Macdonald ME, Gusella JF, Akbarian S, Chen JF, Weng Z, Myers RH.

PLoS Genet. 2014 Feb 27;10(2):e1004188. doi: 10.1371/journal.pgen.1004188. eCollection 2014 Feb.

6.

The co-occurrence of Alzheimer's disease and Huntington's disease: a neuropathological study of 15 elderly Huntington's disease subjects.

Davis MY, Keene CD, Jayadev S, Bird T.

J Huntingtons Dis. 2014;3(2):209-17. doi: 10.3233/JHD-140111.

PMID:
25062863
7.

A common gene expression signature in Huntington's disease patient brain regions.

Neueder A, Bates GP.

BMC Med Genomics. 2014 Oct 30;7:60. doi: 10.1186/s12920-014-0060-2.

8.

miR-10b-5p expression in Huntington's disease brain relates to age of onset and the extent of striatal involvement.

Hoss AG, Labadorf A, Latourelle JC, Kartha VK, Hadzi TC, Gusella JF, MacDonald ME, Chen JF, Akbarian S, Weng Z, Vonsattel JP, Myers RH.

BMC Med Genomics. 2015 Mar 1;8:10. doi: 10.1186/s12920-015-0083-3.

9.

Interrogation of brain miRNA and mRNA expression profiles reveals a molecular regulatory network that is perturbed by mutant huntingtin.

Jin J, Cheng Y, Zhang Y, Wood W, Peng Q, Hutchison E, Mattson MP, Becker KG, Duan W.

J Neurochem. 2012 Nov;123(4):477-90. doi: 10.1111/j.1471-4159.2012.07925.x. Epub 2012 Sep 28.

10.

Huntingtin protein colocalizes with lesions of neurodegenerative diseases: An investigation in Huntington's, Alzheimer's, and Pick's diseases.

Singhrao SK, Thomas P, Wood JD, MacMillan JC, Neal JW, Harper PS, Jones AL.

Exp Neurol. 1998 Apr;150(2):213-22.

PMID:
9527890
11.

Transcriptional alterations related to neuropathology and clinical manifestation of Alzheimer's disease.

Silva AR, Grinberg LT, Farfel JM, Diniz BS, Lima LA, Silva PJ, Ferretti RE, Rocha RM, Filho WJ, Carraro DM, Brentani H.

PLoS One. 2012;7(11):e48751. doi: 10.1371/journal.pone.0048751. Epub 2012 Nov 7.

12.

Wheel running and environmental enrichment differentially modify exon-specific BDNF expression in the hippocampus of wild-type and pre-motor symptomatic male and female Huntington's disease mice.

Zajac MS, Pang TY, Wong N, Weinrich B, Leang LS, Craig JM, Saffery R, Hannan AJ.

Hippocampus. 2010 May;20(5):621-36. doi: 10.1002/hipo.20658.

PMID:
19499586
13.

Characterization of Genetic Networks Associated with Alzheimer's Disease.

Zhang B, Tran L, Emilsson V, Zhu J.

Methods Mol Biol. 2016;1303:459-77. doi: 10.1007/978-1-4939-2627-5_28.

PMID:
26235085
14.

Genome-wide loss of 5-hmC is a novel epigenetic feature of Huntington's disease.

Wang F, Yang Y, Lin X, Wang JQ, Wu YS, Xie W, Wang D, Zhu S, Liao YQ, Sun Q, Yang YG, Luo HR, Guo C, Han C, Tang TS.

Hum Mol Genet. 2013 Sep 15;22(18):3641-53. doi: 10.1093/hmg/ddt214. Epub 2013 May 12.

PMID:
23669348
15.

Differential putaminal morphology in Huntington's disease, frontotemporal dementia and Alzheimer's disease.

Looi JC, Rajagopalan P, Walterfang M, Madsen SK, Thompson PM, Macfarlane MD, Ching C, Chua P, Velakoulis D.

Aust N Z J Psychiatry. 2012 Dec;46(12):1145-58. doi: 10.1177/0004867412457224. Epub 2012 Sep 18.

16.

RNA Sequence Analysis of Human Huntington Disease Brain Reveals an Extensive Increase in Inflammatory and Developmental Gene Expression.

Labadorf A, Hoss AG, Lagomarsino V, Latourelle JC, Hadzi TC, Bregu J, MacDonald ME, Gusella JF, Chen JF, Akbarian S, Weng Z, Myers RH.

PLoS One. 2015 Dec 4;10(12):e0143563. doi: 10.1371/journal.pone.0143563. eCollection 2015. Erratum in: PLoS One. 2016;11(7):e0160295.

17.

Long non-coding RNAs in Huntington's disease neurodegeneration.

Johnson R.

Neurobiol Dis. 2012 May;46(2):245-54. doi: 10.1016/j.nbd.2011.12.006. Epub 2011 Dec 14. Review.

PMID:
22202438
18.

Depressive symptoms in prodromal Huntington's Disease correlate with Stroop-interference related functional connectivity in the ventromedial prefrontal cortex.

Unschuld PG, Joel SE, Pekar JJ, Reading SA, Oishi K, McEntee J, Shanahan M, Bakker A, Margolis RL, Bassett SS, Rosenblatt A, Mori S, van Zijl PC, Ross CA, Redgrave GW.

Psychiatry Res. 2012 Aug-Sep;203(2-3):166-74. doi: 10.1016/j.pscychresns.2012.01.002. Epub 2012 Sep 11.

19.

An Effective Method to Identify Shared Pathways and Common Factors among Neurodegenerative Diseases.

Li P, Nie Y, Yu J.

PLoS One. 2015 Nov 17;10(11):e0143045. doi: 10.1371/journal.pone.0143045. eCollection 2015.

20.

Prefrontal cortex volume reduction on MRI in preclinical Huntington's disease relates to visuomotor performance and CAG number.

Gómez-Ansón B, Alegret M, Muñoz E, Monté GC, Alayrach E, Sánchez A, Boada M, Tolosa E.

Parkinsonism Relat Disord. 2009 Mar;15(3):213-9. doi: 10.1016/j.parkreldis.2008.05.010. Epub 2008 Jul 15.

PMID:
18632301

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