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Items: 1 to 20 of 74

1.

Filamin acts as a key regulator in epithelial defence against transformed cells.

Kajita M, Sugimura K, Ohoka A, Burden J, Suganuma H, Ikegawa M, Shimada T, Kitamura T, Shindoh M, Ishikawa S, Yamamoto S, Saitoh S, Yako Y, Takahashi R, Okajima T, Kikuta J, Maijima Y, Ishii M, Tada M, Fujita Y.

Nat Commun. 2014 Jul 31;5:4428. doi: 10.1038/ncomms5428.

PMID:
25079702
2.

EPLIN is a crucial regulator for extrusion of RasV12-transformed cells.

Ohoka A, Kajita M, Ikenouchi J, Yako Y, Kitamoto S, Kon S, Ikegawa M, Shimada T, Ishikawa S, Fujita Y.

J Cell Sci. 2015 Feb 15;128(4):781-9. doi: 10.1242/jcs.163113. Epub 2015 Jan 20.

3.

A role of the sphingosine-1-phosphate (S1P)-S1P receptor 2 pathway in epithelial defense against cancer (EDAC).

Yamamoto S, Yako Y, Fujioka Y, Kajita M, Kameyama T, Kon S, Ishikawa S, Ohba Y, Ohno Y, Kihara A, Fujita Y.

Mol Biol Cell. 2016 Feb 1;27(3):491-9. doi: 10.1091/mbc.E15-03-0161. Epub 2015 Dec 2.

4.

Cell competition with normal epithelial cells promotes apical extrusion of transformed cells through metabolic changes.

Kon S, Ishibashi K, Katoh H, Kitamoto S, Shirai T, Tanaka S, Kajita M, Ishikawa S, Yamauchi H, Yako Y, Kamasaki T, Matsumoto T, Watanabe H, Egami R, Sasaki A, Nishikawa A, Kameda I, Maruyama T, Narumi R, Morita T, Sasaki Y, Enoki R, Honma S, Imamura H, Oshima M, Soga T, Miyazaki JI, Duchen MR, Nam JM, Onodera Y, Yoshioka S, Kikuta J, Ishii M, Imajo M, Nishida E, Fujioka Y, Ohba Y, Sato T, Fujita Y.

Nat Cell Biol. 2017 May;19(5):530-541. doi: 10.1038/ncb3509. Epub 2017 Apr 17.

PMID:
28414314
5.

Interaction with surrounding normal epithelial cells influences signalling pathways and behaviour of Src-transformed cells.

Kajita M, Hogan C, Harris AR, Dupre-Crochet S, Itasaki N, Kawakami K, Charras G, Tada M, Fujita Y.

J Cell Sci. 2010 Jan 15;123(Pt 2):171-80. doi: 10.1242/jcs.057976. Epub 2009 Dec 21.

6.

Obligatory roles of filamin A in E-cadherin-mediated cell-cell adhesion in epidermal keratinocytes.

Tu CL, You M.

J Dermatol Sci. 2014 Feb;73(2):142-51. doi: 10.1016/j.jdermsci.2013.09.007. Epub 2013 Sep 26.

7.

Cyclic AMP-Rap1A signaling mediates cell surface translocation of microvascular smooth muscle α2C-adrenoceptors through the actin-binding protein filamin-2.

Motawea HK, Jeyaraj SC, Eid AH, Mitra S, Unger NT, Ahmed AA, Flavahan NA, Chotani MA.

Am J Physiol Cell Physiol. 2013 Oct 15;305(8):C829-45. doi: 10.1152/ajpcell.00221.2012. Epub 2013 Jul 17.

8.

TDAG51 is an ERK signaling target that opposes ERK-mediated HME16C mammary epithelial cell transformation.

Oberst MD, Beberman SJ, Zhao L, Yin JJ, Ward Y, Kelly K.

BMC Cancer. 2008 Jul 2;8:189. doi: 10.1186/1471-2407-8-189.

9.

Characterization of the interface between normal and transformed epithelial cells.

Hogan C, Dupré-Crochet S, Norman M, Kajita M, Zimmermann C, Pelling AE, Piddini E, Baena-López LA, Vincent JP, Itoh Y, Hosoya H, Pichaud F, Fujita Y.

Nat Cell Biol. 2009 Apr;11(4):460-7. doi: 10.1038/ncb1853. Epub 2009 Mar 15.

PMID:
19287376
10.

Rab5-regulated endocytosis plays a crucial role in apical extrusion of transformed cells.

Saitoh S, Maruyama T, Yako Y, Kajita M, Fujioka Y, Ohba Y, Kasai N, Sugama N, Kon S, Ishikawa S, Hayashi T, Yamazaki T, Tada M, Fujita Y.

Proc Natl Acad Sci U S A. 2017 Mar 21;114(12):E2327-E2336. doi: 10.1073/pnas.1602349114. Epub 2017 Mar 7.

11.

PKA-regulated VASP phosphorylation promotes extrusion of transformed cells from the epithelium.

Anton KA, Sinclair J, Ohoka A, Kajita M, Ishikawa S, Benz PM, Renne T, Balda M, Jorgensen C, Matter K, Fujita Y.

J Cell Sci. 2014 Aug 15;127(Pt 16):3425-33. doi: 10.1242/jcs.149674. Epub 2014 Jun 24.

12.

Filamin B Enhances the Invasiveness of Cancer Cells into 3D Collagen Matrices.

Iguchi Y, Ishihara S, Uchida Y, Tajima K, Mizutani T, Kawabata K, Haga H.

Cell Struct Funct. 2015;40(2):61-7. doi: 10.1247/csf.15001. Epub 2015 Apr 29.

13.

Delineating v-Src downstream effector pathways in transformed myoblasts.

Ciuffini L, Castellani L, Salvati E, Galletti S, Falcone G, Alemà S.

Oncogene. 2008 Jan 17;27(4):528-39. Epub 2007 Jul 16.

PMID:
17637741
15.

Regulation of cell adhesion to collagen via beta1 integrins is dependent on interactions of filamin A with vimentin and protein kinase C epsilon.

Kim H, Nakamura F, Lee W, Hong C, Pérez-Sala D, McCulloch CA.

Exp Cell Res. 2010 Jul 1;316(11):1829-44. doi: 10.1016/j.yexcr.2010.02.007. Epub 2010 Feb 17.

PMID:
20171211
16.

Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts.

Irani K, Xia Y, Zweier JL, Sollott SJ, Der CJ, Fearon ER, Sundaresan M, Finkel T, Goldschmidt-Clermont PJ.

Science. 1997 Mar 14;275(5306):1649-52.

17.

Role of p21 RAS in p210 bcr-abl transformation of murine myeloid cells.

Mandanas RA, Leibowitz DS, Gharehbaghi K, Tauchi T, Burgess GS, Miyazawa K, Jayaram HN, Boswell HS.

Blood. 1993 Sep 15;82(6):1838-47.

19.

Impact of interactions between normal and transformed epithelial cells and the relevance to cancer.

Hogan C.

Cell Mol Life Sci. 2012 Jan;69(2):203-13. doi: 10.1007/s00018-011-0806-3. Epub 2011 Aug 30. Review.

PMID:
21877117
20.

Vimentin and the K-Ras-induced actin-binding protein control inositol-(1,4,5)-trisphosphate receptor redistribution during MDCK cell differentiation.

Dingli F, Parys JB, Loew D, Saule S, Mery L.

J Cell Sci. 2012 Nov 15;125(Pt 22):5428-40. doi: 10.1242/jcs.108738. Epub 2012 Sep 3.

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