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Items: 1 to 20 of 101


Highly multiplexed and reproducible ion-current-based strategy for large-scale quantitative proteomics and the application to protein expression dynamics induced by methylprednisolone in 60 rats.

Nouri-Nigjeh E, Sukumaran S, Tu C, Li J, Shen X, Duan X, DuBois DC, Almon RR, Jusko WJ, Qu J.

Anal Chem. 2014 Aug 19;86(16):8149-57. doi: 10.1021/ac501380s. Epub 2014 Aug 6.


Reproducible ion-current-based approach for 24-plex comparison of the tissue proteomes of hibernating versus normal myocardium in swine models.

Qu J, Young R, Page BJ, Shen X, Tata N, Li J, Duan X, Fallavollita JA, Canty JM Jr.

J Proteome Res. 2014 May 2;13(5):2571-84. doi: 10.1021/pr5000472. Epub 2014 Apr 4.


Ion-current-based proteomic profiling of the retina in a rat model of Smith-Lemli-Opitz syndrome.

Tu C, Li J, Jiang X, Sheflin LG, Pfeffer BA, Behringer M, Fliesler SJ, Qu J.

Mol Cell Proteomics. 2013 Dec;12(12):3583-98. doi: 10.1074/mcp.M113.027847. Epub 2013 Aug 26.


Proteomic profiling of the retinas in a neonatal rat model of oxygen-induced retinopathy with a reproducible ion-current-based MS1 approach.

Tu C, Beharry KD, Shen X, Li J, Wang L, Aranda JV, Qu J.

J Proteome Res. 2015 May 1;14(5):2109-20. doi: 10.1021/pr501238m. Epub 2015 Apr 6.


An IonStar Experimental Strategy for MS1 Ion Current-Based Quantification Using Ultrahigh-Field Orbitrap: Reproducible, In-Depth, and Accurate Protein Measurement in Large Cohorts.

Shen X, Shen S, Li J, Hu Q, Nie L, Tu C, Wang X, Orsburn B, Wang J, Qu J.

J Proteome Res. 2017 May 25. doi: 10.1021/acs.jproteome.7b00061. [Epub ahead of print]


Experimental Null Method to Guide the Development of Technical Procedures and to Control False-Positive Discovery in Quantitative Proteomics.

Shen X, Hu Q, Li J, Wang J, Qu J.

J Proteome Res. 2015 Oct 2;14(10):4147-57. doi: 10.1021/acs.jproteome.5b00200. Epub 2015 Sep 1.


Functional proteomic analysis of corticosteroid pharmacodynamics in rat liver: Relationship to hepatic stress, signaling, energy regulation, and drug metabolism.

Ayyar VS, Almon RR, DuBois DC, Sukumaran S, Qu J, Jusko WJ.

J Proteomics. 2017 May 8;160:84-105. doi: 10.1016/j.jprot.2017.03.007. Epub 2017 Mar 14.


Evaluating multiplexed quantitative phosphopeptide analysis on a hybrid quadrupole mass filter/linear ion trap/orbitrap mass spectrometer.

Erickson BK, Jedrychowski MP, McAlister GC, Everley RA, Kunz R, Gygi SP.

Anal Chem. 2015 Jan 20;87(2):1241-9. doi: 10.1021/ac503934f. Epub 2015 Jan 6.


Large-scale, ion-current-based proteomics investigation of bronchoalveolar lavage fluid in chronic obstructive pulmonary disease patients.

Tu C, Mammen MJ, Li J, Shen X, Jiang X, Hu Q, Wang J, Sethi S, Qu J.

J Proteome Res. 2014 Feb 7;13(2):627-39. doi: 10.1021/pr4007602. Epub 2013 Dec 2.


Ion-Current-Based Temporal Proteomic Profiling of Influenza-A-Virus-Infected Mouse Lungs Revealed Underlying Mechanisms of Altered Integrity of the Lung Microvascular Barrier.

Shen S, Li J, Hilchey S, Shen X, Tu C, Qiu X, Ng A, Ghaemmaghami S, Wu H, Zand MS, Qu J.

J Proteome Res. 2016 Feb 5;15(2):540-53. doi: 10.1021/acs.jproteome.5b00927. Epub 2016 Jan 8.


High-throughput absolute quantification of proteins using an improved two-dimensional reversed-phase separation and quantification concatemer (QconCAT) approach.

Wei J, Ding C, Zhang J, Mi W, Zhao Y, Liu M, Fu T, Zhang Y, Ying W, Cai Y, Qin J, Qian X.

Anal Bioanal Chem. 2014 Jul;406(17):4183-93. doi: 10.1007/s00216-014-7784-x. Epub 2014 Apr 24.


Gene arrays and temporal patterns of drug response: corticosteroid effects on rat liver.

Almon RR, DuBois DC, Pearson KE, Stephan DA, Jusko WJ.

Funct Integr Genomics. 2003 Dec;3(4):171-9. Epub 2003 Aug 20.


Development of a pharmaceutical hepatotoxicity biomarker panel using a discovery to targeted proteomics approach.

Collins BC, Miller CA, Sposny A, Hewitt P, Wells M, Gallagher WM, Pennington SR.

Mol Cell Proteomics. 2012 Aug;11(8):394-410. doi: 10.1074/mcp.M111.016493. Epub 2012 Apr 23.


Microarray analysis of the temporal response of skeletal muscle to methylprednisolone: comparative analysis of two dosing regimens.

Almon RR, DuBois DC, Yao Z, Hoffman EP, Ghimbovschi S, Jusko WJ.

Physiol Genomics. 2007 Aug 20;30(3):282-99. Epub 2007 May 1.


Optimized procedure of extraction, purification and proteomic analysis of nuclear proteins from mouse brain.

Jankowska U, Latosinska A, Skupien-Rabian B, Swiderska B, Dziedzicka-Wasylewska M, Kedracka-Krok S.

J Neurosci Methods. 2016 Mar 1;261:1-9. doi: 10.1016/j.jneumeth.2015.12.002. Epub 2015 Dec 14.


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