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Items: 1 to 20 of 100

1.

Chronic hypoxia-inducible transcription factor-2 activation stably transforms juxtaglomerular renin cells into fibroblast-like cells in vivo.

Kurt B, Gerl K, Karger C, Schwarzensteiner I, Kurtz A.

J Am Soc Nephrol. 2015 Mar;26(3):587-96. doi: 10.1681/ASN.2013111152. Epub 2014 Jul 28.

2.

Deletion of von Hippel-Lindau protein converts renin-producing cells into erythropoietin-producing cells.

Kurt B, Paliege A, Willam C, Schwarzensteiner I, Schucht K, Neymeyer H, Sequeira-Lopez ML, Bachmann S, Gomez RA, Eckardt KU, Kurtz A.

J Am Soc Nephrol. 2013 Feb;24(3):433-44. doi: 10.1681/ASN.2012080791. Epub 2013 Feb 7.

4.

Action of hypoxia-inducible factor in liver and kidney from mice with Pax8-rtTA-based deletion of von Hippel-Lindau protein.

Mathia S, Paliege A, Koesters R, Peters H, Neumayer HH, Bachmann S, Rosenberger C.

Acta Physiol (Oxf). 2013 Mar;207(3):565-76. doi: 10.1111/apha.12058.

PMID:
23384425
5.

Hypoxia-inducible factor-2 (HIF-2) regulates hepatic erythropoietin in vivo.

Rankin EB, Biju MP, Liu Q, Unger TL, Rha J, Johnson RS, Simon MC, Keith B, Haase VH.

J Clin Invest. 2007 Apr;117(4):1068-77.

7.

Erythropoietin production by PDGFR-β(+) cells.

Gerl K, Nolan KA, Karger C, Fuchs M, Wenger RH, Stolt CC, Willam C, Kurtz A, Kurt B.

Pflugers Arch. 2016 Aug;468(8):1479-87. doi: 10.1007/s00424-016-1829-2. Epub 2016 May 25.

PMID:
27220347
9.

Kelch-like 20 up-regulates the expression of hypoxia-inducible factor-2α through hypoxia- and von Hippel-Lindau tumor suppressor protein-independent regulatory mechanisms.

Higashimura Y, Terai T, Yamaji R, Mitani T, Ogawa M, Harada N, Inui H, Nakano Y.

Biochem Biophys Res Commun. 2011 Sep 23;413(2):201-5. doi: 10.1016/j.bbrc.2011.08.058. Epub 2011 Aug 24.

PMID:
21888897
10.

The VHL tumor suppressor and HIF: insights from genetic studies in mice.

Kapitsinou PP, Haase VH.

Cell Death Differ. 2008 Apr;15(4):650-9. doi: 10.1038/sj.cdd.4402313. Epub 2008 Jan 25. Review.

11.

Activation of Hypoxia Signaling in Stromal Progenitors Impairs Kidney Development.

Gerl K, Steppan D, Fuchs M, Wagner C, Willam C, Kurtz A, Kurt B.

Am J Pathol. 2017 Jul;187(7):1496-1511. doi: 10.1016/j.ajpath.2017.03.014. Epub 2017 May 17.

PMID:
28527294
12.

Expression of hypoxia-inducible factor 1alpha, hypoxia-inducible factor 2alpha, and von Hippel-Lindau protein in epithelial ovarian neoplasms and allelic loss of von Hippel-Lindau gene: nuclear expression of hypoxia-inducible factor 1alpha is an independent prognostic factor in ovarian carcinoma.

Osada R, Horiuchi A, Kikuchi N, Yoshida J, Hayashi A, Ota M, Katsuyama Y, Melillo G, Konishi I.

Hum Pathol. 2007 Sep;38(9):1310-20. Epub 2007 Jun 6. Erratum in: Hum Pathol. 2008 Jan;39(1):147. Mellilo, Giovanni [corrected to Melillo, Giovanni].

PMID:
17555795
13.

Inactivation of the arylhydrocarbon receptor nuclear translocator (Arnt) suppresses von Hippel-Lindau disease-associated vascular tumors in mice.

Rankin EB, Higgins DF, Walisser JA, Johnson RS, Bradfield CA, Haase VH.

Mol Cell Biol. 2005 Apr;25(8):3163-72.

14.

Renal tubular HIF-2α expression requires VHL inactivation and causes fibrosis and cysts.

Schietke RE, Hackenbeck T, Tran M, Günther R, Klanke B, Warnecke CL, Knaup KX, Shukla D, Rosenberger C, Koesters R, Bachmann S, Betz P, Schley G, Schödel J, Willam C, Winkler T, Amann K, Eckardt KU, Maxwell P, Wiesener MS.

PLoS One. 2012;7(1):e31034. doi: 10.1371/journal.pone.0031034. Epub 2012 Jan 27.

15.

Identification of cyclin D1 and other novel targets for the von Hippel-Lindau tumor suppressor gene by expression array analysis and investigation of cyclin D1 genotype as a modifier in von Hippel-Lindau disease.

Zatyka M, da Silva NF, Clifford SC, Morris MR, Wiesener MS, Eckardt KU, Houlston RS, Richards FM, Latif F, Maher ER.

Cancer Res. 2002 Jul 1;62(13):3803-11. Erratum in: Cancer Res. 2015 Sep 15;75(18):3993.

16.
17.

Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein.

Cockman ME, Masson N, Mole DR, Jaakkola P, Chang GW, Clifford SC, Maher ER, Pugh CW, Ratcliffe PJ, Maxwell PH.

J Biol Chem. 2000 Aug 18;275(33):25733-41.

18.

Pancreatic endocrine microadenomatosis in patients with von Hippel-Lindau disease: characterization by VHL/HIF pathway proteins expression.

Périgny M, Hammel P, Corcos O, Larochelle O, Giraud S, Richard S, Sauvanet A, Belghiti J, Ruszniewski P, Bedossa P, Couvelard A.

Am J Surg Pathol. 2009 May;33(5):739-48. doi: 10.1097/PAS.0b013e3181967992.

PMID:
19238077
19.

The protein tyrosine phosphatase receptor type J is regulated by the pVHL-HIF axis in clear cell renal cell carcinoma.

Casagrande S, Ruf M, Rechsteiner M, Morra L, Brun-Schmid S, von Teichman A, Krek W, Schraml P, Moch H.

J Pathol. 2013 Mar;229(4):525-34. doi: 10.1002/path.4107. Epub 2013 Jan 21.

20.

Hypoxia-inducible factor-2α mediates the adaptive increase of intestinal ferroportin during iron deficiency in mice.

Taylor M, Qu A, Anderson ER, Matsubara T, Martin A, Gonzalez FJ, Shah YM.

Gastroenterology. 2011 Jun;140(7):2044-55. doi: 10.1053/j.gastro.2011.03.007. Epub 2011 Mar 17.

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