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Items: 1 to 20 of 223

1.

Claudin 2 deficiency reduces bile flow and increases susceptibility to cholesterol gallstone disease in mice.

Matsumoto K, Imasato M, Yamazaki Y, Tanaka H, Watanabe M, Eguchi H, Nagano H, Hikita H, Tatsumi T, Takehara T, Tamura A, Tsukita S.

Gastroenterology. 2014 Nov;147(5):1134-45.e10. doi: 10.1053/j.gastro.2014.07.033. Epub 2014 Jul 25.

PMID:
25068494
2.

Activation of the Hypoxia Inducible Factor 1α Subunit Pathway in Steatotic Liver Contributes to Formation of Cholesterol Gallstones.

Asai Y, Yamada T, Tsukita S, Takahashi K, Maekawa M, Honma M, Ikeda M, Murakami K, Munakata Y, Shirai Y, Kodama S, Sugisawa T, Chiba Y, Kondo Y, Kaneko K, Uno K, Sawada S, Imai J, Nakamura Y, Yamaguchi H, Tanaka K, Sasano H, Mano N, Ueno Y, Shimosegawa T, Katagiri H.

Gastroenterology. 2017 May;152(6):1521-1535.e8. doi: 10.1053/j.gastro.2017.01.001. Epub 2017 Jan 11.

3.

The hepatobiliary paracellular pathway: a paradigm revisited.

Boyer JL.

Gastroenterology. 2014 Nov;147(5):965-8. doi: 10.1053/j.gastro.2014.09.018. Epub 2014 Sep 26. No abstract available.

PMID:
25263297
4.

Loss of claudins 2 and 15 from mice causes defects in paracellular Na+ flow and nutrient transport in gut and leads to death from malnutrition.

Wada M, Tamura A, Takahashi N, Tsukita S.

Gastroenterology. 2013 Feb;144(2):369-80. doi: 10.1053/j.gastro.2012.10.035. Epub 2012 Oct 23.

PMID:
23089202
5.

Claudin-2-deficient mice are defective in the leaky and cation-selective paracellular permeability properties of renal proximal tubules.

Muto S, Hata M, Taniguchi J, Tsuruoka S, Moriwaki K, Saitou M, Furuse K, Sasaki H, Fujimura A, Imai M, Kusano E, Tsukita S, Furuse M.

Proc Natl Acad Sci U S A. 2010 Apr 27;107(17):8011-6. doi: 10.1073/pnas.0912901107. Epub 2010 Apr 12.

6.

Evidence for a role of claudin 2 as a proximal tubular stress responsive paracellular water channel.

Wilmes A, Aschauer L, Limonciel A, Pfaller W, Jennings P.

Toxicol Appl Pharmacol. 2014 Sep 1;279(2):163-72. doi: 10.1016/j.taap.2014.05.013. Epub 2014 Jun 5.

PMID:
24907557
7.

Claudin-2, a component of the tight junction, forms a paracellular water channel.

Rosenthal R, Milatz S, Krug SM, Oelrich B, Schulzke JD, Amasheh S, Günzel D, Fromm M.

J Cell Sci. 2010 Jun 1;123(Pt 11):1913-21. doi: 10.1242/jcs.060665. Epub 2010 May 11.

8.

Knockout mice reveal key roles for claudin 18 in alveolar barrier properties and fluid homeostasis.

Li G, Flodby P, Luo J, Kage H, Sipos A, Gao D, Ji Y, Beard LL, Marconett CN, DeMaio L, Kim YH, Kim KJ, Laird-Offringa IA, Minoo P, Liebler JM, Zhou B, Crandall ED, Borok Z.

Am J Respir Cell Mol Biol. 2014 Aug;51(2):210-22. doi: 10.1165/rcmb.2013-0353OC.

9.

Paracellular barrier and channel functions of TJ claudins in organizing biological systems: advances in the field of barriology revealed in knockout mice.

Tamura A, Tsukita S.

Semin Cell Dev Biol. 2014 Dec;36:177-85. doi: 10.1016/j.semcdb.2014.09.019. Epub 2014 Oct 12. Review.

PMID:
25305579
10.

Ezetimibe prevents cholesterol gallstone formation in mice.

Zúñiga S, Molina H, Azocar L, Amigo L, Nervi F, Pimentel F, Jarufe N, Arrese M, Lammert F, Miquel JF.

Liver Int. 2008 Aug;28(7):935-47. doi: 10.1111/j.1478-3231.2008.01808.x.

PMID:
18783541
11.

Water channels and barriers formed by claudins.

Rosenthal R, Günzel D, Theune D, Czichos C, Schulzke JD, Fromm M.

Ann N Y Acad Sci. 2017 Jun;1397(1):100-109. doi: 10.1111/nyas.13383. Review.

PMID:
28636801
12.

Niemann-Pick C2 protein expression regulates lithogenic diet-induced gallstone formation and dietary cholesterol metabolism in mice.

Balboa E, Morales G, Aylwin P, Carrasco G, Amigo L, Castro J, Rigotti A, Zanlungo S.

Lipids. 2012 Jan;47(1):13-25. doi: 10.1007/s11745-011-3625-2. Epub 2011 Oct 30.

PMID:
22038687
13.

Hepatic cholesterol transport from plasma into bile: implications for gallstone disease.

Zanlungo S, Rigotti A, Nervi F.

Curr Opin Lipidol. 2004 Jun;15(3):279-86. Review.

PMID:
15166783
14.

Oncostatin M induces upregulation of claudin-2 in rodent hepatocytes coinciding with changes in morphology and function of tight junctions.

Imamura M, Kojima T, Lan M, Son S, Murata M, Osanai M, Chiba H, Hirata K, Sawada N.

Exp Cell Res. 2007 May 15;313(9):1951-62. Epub 2007 Mar 20.

PMID:
17434483
15.

Transgenic overexpression of Niemann-Pick C2 protein promotes cholesterol gallstone formation in mice.

Acuña M, González-Hódar L, Amigo L, Castro J, Morales MG, Cancino GI, Groen AK, Young J, Miquel JF, Zanlungo S.

J Hepatol. 2016 Feb;64(2):361-369. doi: 10.1016/j.jhep.2015.10.002. Epub 2015 Dec 10.

PMID:
26453970
16.
17.

PXR prevents cholesterol gallstone disease by regulating biosynthesis and transport of bile salts.

He J, Nishida S, Xu M, Makishima M, Xie W.

Gastroenterology. 2011 Jun;140(7):2095-106. doi: 10.1053/j.gastro.2011.02.055. Epub 2011 Feb 24.

18.

Pathophysiological preconditions promoting mixed "black" pigment plus cholesterol gallstones in a DeltaF508 mouse model of cystic fibrosis.

Freudenberg F, Leonard MR, Liu SA, Glickman JN, Carey MC.

Am J Physiol Gastrointest Liver Physiol. 2010 Jul;299(1):G205-14. doi: 10.1152/ajpgi.00341.2009. Epub 2010 Apr 29.

19.

Association of caveolin-3 and cholecystokinin A receptor with cholesterol gallstone disease in mice.

Xu GQ, Xu CF, Chen HT, Liu S, Teng XD, Xu GY, Yu CH.

World J Gastroenterol. 2014 Jul 28;20(28):9513-8. doi: 10.3748/wjg.v20.i28.9513.

20.

Deficiency of Niemann-Pick C1 protein protects against diet-induced gallstone formation in mice.

Morales MG, Amigo L, Balboa E, Acuña M, Castro J, Molina H, Miquel JF, Nervi F, Rigotti A, Zanlungo S.

Liver Int. 2010 Jul;30(6):887-97. doi: 10.1111/j.1478-3231.2010.02230.x. Epub 2010 Apr 8.

PMID:
20408952

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