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Items: 1 to 20 of 354

1.

Caspase-8 modulates dectin-1 and complement receptor 3-driven IL-1β production in response to β-glucans and the fungal pathogen, Candida albicans.

Ganesan S, Rathinam VAK, Bossaller L, Army K, Kaiser WJ, Mocarski ES, Dillon CP, Green DR, Mayadas TN, Levitz SM, Hise AG, Silverman N, Fitzgerald KA.

J Immunol. 2014 Sep 1;193(5):2519-2530. doi: 10.4049/jimmunol.1400276. Epub 2014 Jul 25.

2.

An anti-inflammatory property of Candida albicans β-glucan: Induction of high levels of interleukin-1 receptor antagonist via a Dectin-1/CR3 independent mechanism.

Smeekens SP, Gresnigt MS, Becker KL, Cheng SC, Netea SA, Jacobs L, Jansen T, van de Veerdonk FL, Williams DL, Joosten LA, Dinarello CA, Netea MG.

Cytokine. 2015 Feb;71(2):215-22. doi: 10.1016/j.cyto.2014.10.013. Epub 2014 Nov 20.

3.

(1,3)-beta-glucans activate both dectin-1 and NLRP3 inflammasome in human macrophages.

Kankkunen P, Teirilä L, Rintahaka J, Alenius H, Wolff H, Matikainen S.

J Immunol. 2010 Jun 1;184(11):6335-42. doi: 10.4049/jimmunol.0903019. Epub 2010 Apr 26.

4.

An essential role for the NLRP3 inflammasome in host defense against the human fungal pathogen Candida albicans.

Hise AG, Tomalka J, Ganesan S, Patel K, Hall BA, Brown GD, Fitzgerald KA.

Cell Host Microbe. 2009 May 8;5(5):487-97. doi: 10.1016/j.chom.2009.05.002.

5.

Internalized Cryptococcus neoformans Activates the Canonical Caspase-1 and the Noncanonical Caspase-8 Inflammasomes.

Chen M, Xing Y, Lu A, Fang W, Sun B, Chen C, Liao W, Meng G.

J Immunol. 2015 Nov 15;195(10):4962-72. doi: 10.4049/jimmunol.1500865. Epub 2015 Oct 14.

6.

Dectin-2 is a primary receptor for NLRP3 inflammasome activation in dendritic cell response to Histoplasma capsulatum.

Chang TH, Huang JH, Lin HC, Chen WY, Lee YH, Hsu LC, Netea MG, Ting JP, Wu-Hsieh BA.

PLoS Pathog. 2017 Jul 3;13(7):e1006485. doi: 10.1371/journal.ppat.1006485. eCollection 2017 Jul.

7.

Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1β via a noncanonical caspase-8 inflammasome.

Gringhuis SI, Kaptein TM, Wevers BA, Theelen B, van der Vlist M, Boekhout T, Geijtenbeek TB.

Nat Immunol. 2012 Jan 22;13(3):246-54. doi: 10.1038/ni.2222.

PMID:
22267217
8.

Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence.

Gross O, Poeck H, Bscheider M, Dostert C, Hannesschläger N, Endres S, Hartmann G, Tardivel A, Schweighoffer E, Tybulewicz V, Mocsai A, Tschopp J, Ruland J.

Nature. 2009 May 21;459(7245):433-6. doi: 10.1038/nature07965. Epub 2009 Apr 1.

PMID:
19339971
9.

Involvement of the NLRP3 inflammasome in innate and humoral adaptive immune responses to fungal beta-glucan.

Kumar H, Kumagai Y, Tsuchida T, Koenig PA, Satoh T, Guo Z, Jang MH, Saitoh T, Akira S, Kawai T.

J Immunol. 2009 Dec 15;183(12):8061-7. doi: 10.4049/jimmunol.0902477.

10.

Bypassing pathogen-induced inflammasome activation for the regulation of interleukin-1beta production by the fungal pathogen Candida albicans.

van de Veerdonk FL, Joosten LA, Devesa I, Mora-Montes HM, Kanneganti TD, Dinarello CA, van der Meer JW, Gow NA, Kullberg BJ, Netea MG.

J Infect Dis. 2009 Apr 1;199(7):1087-96. doi: 10.1086/597274. Erratum in: J Infect Dis. 2009 Jun 1;199(11):1716.

PMID:
19222370
11.

Cutting edge: Candida albicans hyphae formation triggers activation of the Nlrp3 inflammasome.

Joly S, Ma N, Sadler JJ, Soll DR, Cassel SL, Sutterwala FS.

J Immunol. 2009 Sep 15;183(6):3578-81. doi: 10.4049/jimmunol.0901323. Epub 2009 Aug 14.

12.

Caspase-11 activation in response to bacterial secretion systems that access the host cytosol.

Casson CN, Copenhaver AM, Zwack EE, Nguyen HT, Strowig T, Javdan B, Bradley WP, Fung TC, Flavell RA, Brodsky IE, Shin S.

PLoS Pathog. 2013;9(6):e1003400. doi: 10.1371/journal.ppat.1003400. Epub 2013 Jun 6.

13.

Cell type-specific differences in β-glucan recognition and signalling in porcine innate immune cells.

Baert K, Sonck E, Goddeeris BM, Devriendt B, Cox E.

Dev Comp Immunol. 2015 Jan;48(1):192-203. doi: 10.1016/j.dci.2014.10.005. Epub 2014 Oct 22.

PMID:
25453580
14.

A novel role for the NLRC4 inflammasome in mucosal defenses against the fungal pathogen Candida albicans.

Tomalka J, Ganesan S, Azodi E, Patel K, Majmudar P, Hall BA, Fitzgerald KA, Hise AG.

PLoS Pathog. 2011 Dec;7(12):e1002379. doi: 10.1371/journal.ppat.1002379. Epub 2011 Dec 8.

15.

Neutrophil IL-1β processing induced by pneumolysin is mediated by the NLRP3/ASC inflammasome and caspase-1 activation and is dependent on K+ efflux.

Karmakar M, Katsnelson M, Malak HA, Greene NG, Howell SJ, Hise AG, Camilli A, Kadioglu A, Dubyak GR, Pearlman E.

J Immunol. 2015 Feb 15;194(4):1763-75. doi: 10.4049/jimmunol.1401624. Epub 2015 Jan 21.

16.

The inflammasome drives protective Th1 and Th17 cellular responses in disseminated candidiasis.

van de Veerdonk FL, Joosten LA, Shaw PJ, Smeekens SP, Malireddi RK, van der Meer JW, Kullberg BJ, Netea MG, Kanneganti TD.

Eur J Immunol. 2011 Aug;41(8):2260-8. doi: 10.1002/eji.201041226. Epub 2011 Jul 4.

17.

Activation of inflammasomes in dendritic cells and macrophages by Mycoplasma salivarium.

Sugiyama M, Saeki A, Hasebe A, Kamesaki R, Yoshida Y, Kitagawa Y, Suzuki T, Shibata K.

Mol Oral Microbiol. 2016 Jun;31(3):259-69. doi: 10.1111/omi.12117. Epub 2015 Sep 4.

PMID:
26177301
18.

Deficient NLRP3 and AIM2 Inflammasome Function in Autoimmune NZB Mice.

Sester DP, Sagulenko V, Thygesen SJ, Cridland JA, Loi YS, Cridland SO, Masters SL, Genske U, Hornung V, Andoniou CE, Sweet MJ, Degli-Esposti MA, Schroder K, Stacey KJ.

J Immunol. 2015 Aug 1;195(3):1233-41. doi: 10.4049/jimmunol.1402859. Epub 2015 Jun 26.

19.

FcγR mediates TLR2- and Syk-dependent NLRP3 inflammasome activation by inactivated Francisella tularensis LVS immune complexes.

Duffy EB, Periasamy S, Hunt D, Drake JR, Harton JA.

J Leukoc Biol. 2016 Dec;100(6):1335-1347. Epub 2016 Jun 30.

20.

Schistosoma mansoni triggers Dectin-2, which activates the Nlrp3 inflammasome and alters adaptive immune responses.

Ritter M, Gross O, Kays S, Ruland J, Nimmerjahn F, Saijo S, Tschopp J, Layland LE, Prazeres da Costa C.

Proc Natl Acad Sci U S A. 2010 Nov 23;107(47):20459-64. doi: 10.1073/pnas.1010337107. Epub 2010 Nov 8.

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