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Items: 1 to 20 of 143

1.

Targeting the HA2 subunit of influenza A virus hemagglutinin via CD40L provides universal protection against diverse subtypes.

Fan X, Hashem AM, Chen Z, Li C, Doyle T, Zhang Y, Yi Y, Farnsworth A, Xu K, Li Z, He R, Li X, Wang J.

Mucosal Immunol. 2015 Jan;8(1):211-20. doi: 10.1038/mi.2014.59. Epub 2014 Jul 23.

2.

Heterosubtypic protection against influenza A induced by adenylate cyclase toxoids delivering conserved HA2 subunit of hemagglutinin.

Staneková Z, Adkins I, Kosová M, Janulíková J, Sebo P, Varečková E.

Antiviral Res. 2013 Jan;97(1):24-35. doi: 10.1016/j.antiviral.2012.09.008. Epub 2012 Oct 2.

PMID:
23036818
3.

Unmasking Stem-Specific Neutralizing Epitopes by Abolishing N-Linked Glycosylation Sites of Influenza Virus Hemagglutinin Proteins for Vaccine Design.

Liu WC, Jan JT, Huang YJ, Chen TH, Wu SC.

J Virol. 2016 Sep 12;90(19):8496-508. doi: 10.1128/JVI.00880-16. Print 2016 Oct 1.

4.

A Bivalent Heterologous DNA Virus-Like-Particle Prime-Boost Vaccine Elicits Broad Protection against both Group 1 and 2 Influenza A Viruses.

Jiang W, Wang S, Chen H, Ren H, Huang X, Wang G, Chen Z, Chen L, Chen Z, Zhou P.

J Virol. 2017 Apr 13;91(9). pii: e02052-16. doi: 10.1128/JVI.02052-16. Print 2017 May 1.

PMID:
28179535
5.

Antibodies induced by the HA2 glycopolypeptide of influenza virus haemagglutinin improve recovery from influenza A virus infection.

Gocník M, Fislová T, Mucha V, Sládková T, Russ G, Kostolansky F, Varecková E.

J Gen Virol. 2008 Apr;89(Pt 4):958-67. doi: 10.1099/vir.0.83524-0.

PMID:
18343837
6.

Evaluation of the immunogenicity and protective effects of a trivalent chimeric norovirus P particle immunogen displaying influenza HA2 from subtypes H1, H3 and B.

Gong X, Yin H, Shi Y, He X, Yu Y, Guan S, Kuai Z, Haji NM, Haji NM, Kong W, Shan Y.

Emerg Microbes Infect. 2016 May 25;5:e51. doi: 10.1038/emi.2016.51.

7.

Cross-protection of Lactococcus lactis-displayed HA2 subunit against homologous and heterologous influenza A viruses in mice.

Lei H, Peng X, Zhao D, Jiao H, Ouyang J.

Arch Virol. 2015 Dec;160(12):3011-9. doi: 10.1007/s00705-015-2587-8. Epub 2015 Sep 11.

PMID:
26358264
8.

Intranasal adenovirus-vectored vaccine for induction of long-lasting humoral immunity-mediated broad protection against influenza in mice.

Kim EH, Park HJ, Han GY, Song MK, Pereboev A, Hong JS, Chang J, Byun YH, Seong BL, Nguyen HH.

J Virol. 2014 Sep 1;88(17):9693-703. doi: 10.1128/JVI.00823-14. Epub 2014 Jun 11.

9.

CD40 ligand preferentially modulates immune response and enhances protection against influenza virus.

Hashem AM, Gravel C, Chen Z, Yi Y, Tocchi M, Jaentschke B, Fan X, Li C, Rosu-Myles M, Pereboev A, He R, Wang J, Li X.

J Immunol. 2014 Jul 15;193(2):722-34. doi: 10.4049/jimmunol.1300093. Epub 2014 Jun 13.

10.

Vaccine-induced anti-HA2 antibodies promote virus fusion and enhance influenza virus respiratory disease.

Khurana S, Loving CL, Manischewitz J, King LR, Gauger PC, Henningson J, Vincent AL, Golding H.

Sci Transl Med. 2013 Aug 28;5(200):200ra114. doi: 10.1126/scitranslmed.3006366.

11.

Recombinant influenza A virus hemagglutinin HA2 subunit protects mice against influenza A(H7N9) virus infection.

To KK, Zhang AJ, Chan AS, Li C, Cai JP, Lau CC, Li CG, Jahan AS, Wu WL, Li L, Tsang AK, Chan KH, Chen H, Yuen KY.

Arch Virol. 2015 Mar;160(3):777-86. doi: 10.1007/s00705-014-2314-x. Epub 2015 Jan 24.

PMID:
25616843
12.

Design of an HA2-based Escherichia coli expressed influenza immunogen that protects mice from pathogenic challenge.

Bommakanti G, Citron MP, Hepler RW, Callahan C, Heidecker GJ, Najar TA, Lu X, Joyce JG, Shiver JW, Casimiro DR, ter Meulen J, Liang X, Varadarajan R.

Proc Natl Acad Sci U S A. 2010 Aug 3;107(31):13701-6. doi: 10.1073/pnas.1007465107. Epub 2010 Jul 6.

13.

Heterosubtypic antiviral activity of hemagglutinin-specific antibodies induced by intranasal immunization with inactivated influenza viruses in mice.

Muramatsu M, Yoshida R, Miyamoto H, Tomabechi D, Kajihara M, Maruyama J, Kimura T, Manzoor R, Ito K, Takada A.

PLoS One. 2013 Aug 16;8(8):e71534. doi: 10.1371/journal.pone.0071534. eCollection 2013.

14.

Intermonomer Interactions in Hemagglutinin Subunits HA1 and HA2 Affecting Hemagglutinin Stability and Influenza Virus Infectivity.

Wang W, DeFeo CJ, Alvarado-Facundo E, Vassell R, Weiss CD.

J Virol. 2015 Oct;89(20):10602-11. doi: 10.1128/JVI.00939-15. Epub 2015 Aug 12.

15.

Heterosubtypic protective immunity against influenza A virus induced by fusion peptide of the hemagglutinin in comparison to ectodomain of M2 protein.

Staneková Z, Király J, Stropkovská A, Mikušková T, Mucha V, Kostolanský F, Varečková E.

Acta Virol. 2011;55(1):61-7.

PMID:
21434706
16.

The highly conserved HA2 protein of the influenza A virus induces a cross protective immune response.

Lee JS, Chowdhury MY, Moon HJ, Choi YK, Talactac MR, Kim JH, Park ME, Son HY, Shin KS, Kim CJ.

J Virol Methods. 2013 Dec;194(1-2):280-8. doi: 10.1016/j.jviromet.2013.08.022. Epub 2013 Sep 1.

PMID:
24004822
17.

Vaccination with a synthetic peptide from the influenza virus hemagglutinin provides protection against distinct viral subtypes.

Wang TT, Tan GS, Hai R, Pica N, Ngai L, Ekiert DC, Wilson IA, García-Sastre A, Moran TM, Palese P.

Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):18979-84. doi: 10.1073/pnas.1013387107. Epub 2010 Oct 18.

18.

Intranasal immunization of baculovirus displayed hemagglutinin confers complete protection against mouse adapted highly pathogenic H7N7 reassortant influenza virus.

Rajesh Kumar S, Syed Khader SM, Kiener TK, Szyporta M, Kwang J.

PLoS One. 2013 Jun 7;8(6):e63856. doi: 10.1371/journal.pone.0063856. Print 2013.

19.

Mucosally administered Lactobacillus surface-displayed influenza antigens (sM2 and HA2) with cholera toxin subunit A1 (CTA1) Induce broadly protective immune responses against divergent influenza subtypes.

Li R, Chowdhury MY, Kim JH, Kim TH, Pathinayake P, Koo WS, Park ME, Yoon JE, Roh JB, Hong SP, Sung MH, Lee JS, Kim CJ.

Vet Microbiol. 2015 Sep 30;179(3-4):250-63. doi: 10.1016/j.vetmic.2015.07.020. Epub 2015 Jul 17.

PMID:
26210951
20.

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