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Items: 1 to 20 of 140

1.

Inhibition of epidermal growth factor signaling by the cardiac glycoside ouabain in medulloblastoma.

Wolle D, Lee SJ, Li Z, Litan A, Barwe SP, Langhans SA.

Cancer Med. 2014 Oct;3(5):1146-58. doi: 10.1002/cam4.314. Epub 2014 Jul 23.

2.

Ammonia-induced Na,K-ATPase/ouabain-mediated EGF receptor transactivation, MAPK/ERK and PI3K/AKT signaling and ROS formation cause astrocyte swelling.

Dai H, Song D, Xu J, Li B, Hertz L, Peng L.

Neurochem Int. 2013 Nov;63(6):610-25. doi: 10.1016/j.neuint.2013.09.005. Epub 2013 Sep 14.

PMID:
24044899
3.

Association of PI3K-Akt signaling pathway with digitalis-induced hypertrophy of cardiac myocytes.

Liu L, Zhao X, Pierre SV, Askari A.

Am J Physiol Cell Physiol. 2007 Nov;293(5):C1489-97. Epub 2007 Aug 29.

4.

Ouabain activates the Na-K-ATPase signalosome to induce autosomal dominant polycystic kidney disease cell proliferation.

Nguyen AN, Jansson K, Sánchez G, Sharma M, Reif GA, Wallace DP, Blanco G.

Am J Physiol Renal Physiol. 2011 Oct;301(4):F897-906. doi: 10.1152/ajprenal.00095.2011. Epub 2011 Jun 22.

5.

Ischemia/reperfusion-induced alterations of enzymatic and signaling functions of the rat cardiac Na+/K+-ATPase: protection by ouabain preconditioning.

Belliard A, Gulati GK, Duan Q, Alves R, Brewer S, Madan N, Sottejeau Y, Wang X, Kalisz J, Pierre SV.

Physiol Rep. 2016 Oct;4(19). pii: e12991.

6.

Digitalis-induced signaling by Na+/K+-ATPase in human breast cancer cells.

Kometiani P, Liu L, Askari A.

Mol Pharmacol. 2005 Mar;67(3):929-36. Epub 2004 Dec 15.

7.

Molecular mechanisms of Na/K-ATPase-mediated signal transduction.

Xie Z.

Ann N Y Acad Sci. 2003 Apr;986:497-503. Review.

PMID:
12763870
9.

Cardiotoxin III suppresses MDA-MB-231 cell metastasis through the inhibition of EGF/EGFR-mediated signaling pathway.

Tsai PC, Hsieh CY, Chiu CC, Wang CK, Chang LS, Lin SR.

Toxicon. 2012 Oct;60(5):734-43. doi: 10.1016/j.toxicon.2012.05.019. Epub 2012 Jun 7.

PMID:
22683533
10.

Cell signaling associated with Na(+)/K(+)-ATPase: activation of phosphatidylinositide 3-kinase IA/Akt by ouabain is independent of Src.

Wu J, Akkuratov EE, Bai Y, Gaskill CM, Askari A, Liu L.

Biochemistry. 2013 Dec 17;52(50):9059-67. doi: 10.1021/bi4011804. Epub 2013 Nov 23.

11.

Intracerebroventricular administration of ouabain, a Na/K-ATPase inhibitor, activates mTOR signal pathways and protein translation in the rat frontal cortex.

Kim SH, Yu HS, Park HG, Ha K, Kim YS, Shin SY, Ahn YM.

Prog Neuropsychopharmacol Biol Psychiatry. 2013 Aug 1;45:73-82. doi: 10.1016/j.pnpbp.2013.04.018. Epub 2013 May 2.

PMID:
23643758
12.

Regulation of ERK1/2 by ouabain and Na-K-ATPase-dependent energy utilization and AMPK activation in parotid acinar cells.

Soltoff SP, Hedden L.

Am J Physiol Cell Physiol. 2008 Sep;295(3):C590-9. doi: 10.1152/ajpcell.00140.2008. Epub 2008 Jul 16.

13.

Cardiac glycoside activities link Na(+)/K(+) ATPase ion-transport to breast cancer cell migration via correlative SAR.

Magpusao AN, Omolloh G, Johnson J, Gascón J, Peczuh MW, Fenteany G.

ACS Chem Biol. 2015 Feb 20;10(2):561-9. doi: 10.1021/cb500665r. Epub 2014 Nov 26.

14.
15.

New insights into the regulation of Na+,K+-ATPase by ouabain.

Silva E, Soares-da-Silva P.

Int Rev Cell Mol Biol. 2012;294:99-132. doi: 10.1016/B978-0-12-394305-7.00002-1. Review.

PMID:
22364872
16.

Na,K-ATPase β1-subunit is a target of sonic hedgehog signaling and enhances medulloblastoma tumorigenicity.

Lee SJ, Litan A, Li Z, Graves B, Lindsey S, Barwe SP, Langhans SA.

Mol Cancer. 2015 Aug 19;14:159. doi: 10.1186/s12943-015-0430-1.

17.

Differential roles of caveolin-1 in ouabain-induced Na+/K+-ATPase cardiac signaling and contractility.

Bai Y, Wu J, Li D, Morgan EE, Liu J, Zhao X, Walsh A, Saikumar J, Tinkel J, Joe B, Gupta R, Liu L.

Physiol Genomics. 2016 Oct 1;48(10):739-748. doi: 10.1152/physiolgenomics.00042.2016. Epub 2016 Aug 12.

18.

Preconditioning by subinotropic doses of ouabain in the Langendorff perfused rabbit heart.

Morgan EE, Li Z, Stebal C, Belliard A, Tennyson G, Salari B, Garlid KD, Pierre SV.

J Cardiovasc Pharmacol. 2010 Mar;55(3):234-9. doi: 10.1097/FJC.0b013e3181ce5e14.

19.

Synergism between Hedgehog-GLI and EGFR signaling in Hedgehog-responsive human medulloblastoma cells induces downregulation of canonical Hedgehog-target genes and stabilized expression of GLI1.

Götschel F, Berg D, Gruber W, Bender C, Eberl M, Friedel M, Sonntag J, Rüngeler E, Hache H, Wierling C, Nietfeld W, Lehrach H, Frischauf A, Schwartz-Albiez R, Aberger F, Korf U.

PLoS One. 2013 Jun 10;8(6):e65403. doi: 10.1371/journal.pone.0065403. Print 2013.

20.

Role of caveolae in signal-transducing function of cardiac Na+/K+-ATPase.

Liu L, Mohammadi K, Aynafshar B, Wang H, Li D, Liu J, Ivanov AV, Xie Z, Askari A.

Am J Physiol Cell Physiol. 2003 Jun;284(6):C1550-60. Epub 2003 Feb 26.

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