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Items: 1 to 20 of 146

1.

Perforin is a novel immune regulator of obesity-related insulin resistance.

Revelo XS, Tsai S, Lei H, Luck H, Ghazarian M, Tsui H, Shi SY, Schroer S, Luk CT, Lin GH, Mak TW, Woo M, Winer S, Winer DA.

Diabetes. 2015 Jan;64(1):90-103. doi: 10.2337/db13-1524. Epub 2014 Jul 21.

2.

Protective Role for B-1b B Cells and IgM in Obesity-Associated Inflammation, Glucose Intolerance, and Insulin Resistance.

Harmon DB, Srikakulapu P, Kaplan JL, Oldham SN, McSkimming C, Garmey JC, Perry HM, Kirby JL, Prohaska TA, Gonen A, Hallowell P, Schirmer B, Tsimikas S, Taylor AM, Witztum JL, McNamara CA.

Arterioscler Thromb Vasc Biol. 2016 Apr;36(4):682-91. doi: 10.1161/ATVBAHA.116.307166. Epub 2016 Feb 11.

3.

TLR9 regulates adipose tissue inflammation and obesity-related metabolic disorders.

Hong CP, Yun CH, Lee GW, Park A, Kim YM, Jang MH.

Obesity (Silver Spring). 2015 Nov;23(11):2199-206. doi: 10.1002/oby.21215. Epub 2015 Aug 11.

4.

Regulation of adipose tissue T cell subsets by Stat3 is crucial for diet-induced obesity and insulin resistance.

Priceman SJ, Kujawski M, Shen S, Cherryholmes GA, Lee H, Zhang C, Kruper L, Mortimer J, Jove R, Riggs AD, Yu H.

Proc Natl Acad Sci U S A. 2013 Aug 6;110(32):13079-84. doi: 10.1073/pnas.1311557110. Epub 2013 Jul 22.

5.

T-lymphocyte infiltration in visceral adipose tissue: a primary event in adipose tissue inflammation and the development of obesity-mediated insulin resistance.

Kintscher U, Hartge M, Hess K, Foryst-Ludwig A, Clemenz M, Wabitsch M, Fischer-Posovszky P, Barth TF, Dragun D, Skurk T, Hauner H, Blüher M, Unger T, Wolf AM, Knippschild U, Hombach V, Marx N.

Arterioscler Thromb Vasc Biol. 2008 Jul;28(7):1304-10. doi: 10.1161/ATVBAHA.108.165100. Epub 2008 Apr 17.

6.

The "Big Bang" in obese fat: Events initiating obesity-induced adipose tissue inflammation.

Wensveen FM, Valentić S, Šestan M, Turk Wensveen T, Polić B.

Eur J Immunol. 2015 Sep;45(9):2446-56. doi: 10.1002/eji.201545502. Epub 2015 Aug 19. Review.

7.

Natural killer T cells are involved in adipose tissues inflammation and glucose intolerance in diet-induced obese mice.

Ohmura K, Ishimori N, Ohmura Y, Tokuhara S, Nozawa A, Horii S, Andoh Y, Fujii S, Iwabuchi K, Onoé K, Tsutsui H.

Arterioscler Thromb Vasc Biol. 2010 Feb;30(2):193-9. doi: 10.1161/ATVBAHA.109.198614. Epub 2009 Nov 12. Erratum in: Arterioscler Thromb Vasc Biol.2010 Sep;30(9):e169.

8.

NK cells link obesity-induced adipose stress to inflammation and insulin resistance.

Wensveen FM, Jelenčić V, Valentić S, Šestan M, Wensveen TT, Theurich S, Glasner A, Mendrila D, Štimac D, Wunderlich FT, Brüning JC, Mandelboim O, Polić B.

Nat Immunol. 2015 Apr;16(4):376-85. doi: 10.1038/ni.3120. Epub 2015 Mar 2.

PMID:
25729921
9.

T-cell profile in adipose tissue is associated with insulin resistance and systemic inflammation in humans.

McLaughlin T, Liu LF, Lamendola C, Shen L, Morton J, Rivas H, Winer D, Tolentino L, Choi O, Zhang H, Hui Yen Chng M, Engleman E.

Arterioscler Thromb Vasc Biol. 2014 Dec;34(12):2637-43. doi: 10.1161/ATVBAHA.114.304636. Epub 2014 Oct 23.

10.

Normalization of obesity-associated insulin resistance through immunotherapy.

Winer S, Chan Y, Paltser G, Truong D, Tsui H, Bahrami J, Dorfman R, Wang Y, Zielenski J, Mastronardi F, Maezawa Y, Drucker DJ, Engleman E, Winer D, Dosch HM.

Nat Med. 2009 Aug;15(8):921-9. doi: 10.1038/nm.2001. Epub 2009 Jul 26.

11.

Oral treatment with γ-aminobutyric acid improves glucose tolerance and insulin sensitivity by inhibiting inflammation in high fat diet-fed mice.

Tian J, Dang HN, Yong J, Chui WS, Dizon MP, Yaw CK, Kaufman DL.

PLoS One. 2011;6(9):e25338. doi: 10.1371/journal.pone.0025338. Epub 2011 Sep 22.

12.

Essential role of CD11a in CD8+ T-cell accumulation and activation in adipose tissue.

Jiang E, Perrard XD, Yang D, Khan IM, Perrard JL, Smith CW, Ballantyne CM, Wu H.

Arterioscler Thromb Vasc Biol. 2014 Jan;34(1):34-43. doi: 10.1161/ATVBAHA.113.302077. Epub 2013 Oct 24.

13.

Attenuated adipose tissue and skeletal muscle inflammation in obese mice with combined CD4+ and CD8+ T cell deficiency.

Khan IM, Dai Perrard XY, Perrard JL, Mansoori A, Smith CW, Wu H, Ballantyne CM.

Atherosclerosis. 2014 Apr;233(2):419-28. doi: 10.1016/j.atherosclerosis.2014.01.011. Epub 2014 Jan 21.

14.

Interferon regulatory factor 7 deficiency prevents diet-induced obesity and insulin resistance.

Wang XA, Zhang R, Zhang S, Deng S, Jiang D, Zhong J, Yang L, Wang T, Hong S, Guo S, She ZG, Zhang XD, Li H.

Am J Physiol Endocrinol Metab. 2013 Aug 15;305(4):E485-95. doi: 10.1152/ajpendo.00505.2012. Epub 2013 May 21.

15.

The specific NK cell response in concert with perforin prevents CD8(+) T cell-mediated immunopathology after mouse cytomegalovirus infection.

Arapović J, Arapović M, Golemac M, Traven L, Tomac J, Rumora D, Ražić E, Krmpotić A, Jonjić S.

Med Microbiol Immunol. 2015 Jun;204(3):335-44. doi: 10.1007/s00430-015-0409-y. Epub 2015 Mar 26.

PMID:
25809566
16.
17.

Systemic inflammation and insulin sensitivity in obese IFN-γ knockout mice.

O'Rourke RW, White AE, Metcalf MD, Winters BR, Diggs BS, Zhu X, Marks DL.

Metabolism. 2012 Aug;61(8):1152-61. doi: 10.1016/j.metabol.2012.01.018. Epub 2012 Mar 3.

18.

IL-33 Reverses an Obesity-Induced Deficit in Visceral Adipose Tissue ST2+ T Regulatory Cells and Ameliorates Adipose Tissue Inflammation and Insulin Resistance.

Han JM, Wu D, Denroche HC, Yao Y, Verchere CB, Levings MK.

J Immunol. 2015 May 15;194(10):4777-83. doi: 10.4049/jimmunol.1500020. Epub 2015 Apr 13.

19.

CD40L deficiency ameliorates adipose tissue inflammation and metabolic manifestations of obesity in mice.

Poggi M, Engel D, Christ A, Beckers L, Wijnands E, Boon L, Driessen A, Cleutjens J, Weber C, Gerdes N, Lutgens E.

Arterioscler Thromb Vasc Biol. 2011 Oct;31(10):2251-60. doi: 10.1161/ATVBAHA.111.231357. Epub 2011 Aug 4.

20.

Long-term exposure to a high-fat diet results in the development of glucose intolerance and insulin resistance in interleukin-1 receptor I-deficient mice.

McGillicuddy FC, Reynolds CM, Finucane O, Coleman E, Harford KA, Grant C, Sergi D, Williams LM, Mills KH, Roche HM.

Am J Physiol Endocrinol Metab. 2013 Oct 1;305(7):E834-44. doi: 10.1152/ajpendo.00297.2013. Epub 2013 Aug 6.

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