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Items: 1 to 20 of 117

1.

Oncogenic role of Merlin/NF2 in glioblastoma.

Guerrero PA, Yin W, Camacho L, Marchetti D.

Oncogene. 2015 May 14;34(20):2621-30. doi: 10.1038/onc.2014.185. Epub 2014 Jul 21.

2.

Moesin-ezrin-radixin-like protein (merlin) mediates protein interacting with the carboxyl terminus-1 (PICT-1)-induced growth inhibition of glioblastoma cells in the nucleus.

Chen H, Mei L, Zhou L, Zhang X, Guo C, Li J, Wang H, Zhu Y, Zheng Y, Huang L.

Int J Biochem Cell Biol. 2011 Apr;43(4):545-55. doi: 10.1016/j.biocel.2010.12.011. Epub 2010 Dec 15.

PMID:
21167305
3.

Compensative shuttling of merlin to phosphorylation on serine 518 in vestibular schwannoma.

Lü J, Zou J, Wu H, Cai L.

Laryngoscope. 2008 Jan;118(1):169-74.

PMID:
17989580
4.

ADAM17 regulates epidermal growth factor receptor expression through the activation of Notch1 in non-small cell lung cancer.

Baumgart A, Seidl S, Vlachou P, Michel L, Mitova N, Schatz N, Specht K, Koch I, Schuster T, Grundler R, Kremer M, Fend F, Siveke JT, Peschel C, Duyster J, Dechow T.

Cancer Res. 2010 Jul 1;70(13):5368-78. doi: 10.1158/0008-5472.CAN-09-3763. Epub 2010 Jun 15.

5.

Merlin/NF2 regulates angiogenesis in schwannomas through a Rac1/semaphorin 3F-dependent mechanism.

Wong HK, Shimizu A, Kirkpatrick ND, Garkavtsev I, Chan AW, di Tomaso E, Klagsbrun M, Jain RK.

Neoplasia. 2012 Feb;14(2):84-94.

6.

The NF2 tumor suppressor gene product, merlin, inhibits cell proliferation and cell cycle progression by repressing cyclin D1 expression.

Xiao GH, Gallagher R, Shetler J, Skele K, Altomare DA, Pestell RG, Jhanwar S, Testa JR.

Mol Cell Biol. 2005 Mar;25(6):2384-94.

7.

Effect of merlin phosphorylation on neurofibromatosis 2 (NF2) gene function.

Surace EI, Haipek CA, Gutmann DH.

Oncogene. 2004 Jan 15;23(2):580-7.

PMID:
14724586
8.

Overexpression of ezrin inactivates NF2 tumor suppressor in glioblastoma.

Morales FC, Molina JR, Hayashi Y, Georgescu MM.

Neuro Oncol. 2010 Jun;12(6):528-39. doi: 10.1093/neuonc/nop060. Epub 2010 Feb 14.

9.

p21-activated kinase links Rac/Cdc42 signaling to merlin.

Xiao GH, Beeser A, Chernoff J, Testa JR.

J Biol Chem. 2002 Jan 11;277(2):883-6. Epub 2001 Nov 21.

10.

Merlin is a potent inhibitor of glioma growth.

Lau YK, Murray LB, Houshmandi SS, Xu Y, Gutmann DH, Yu Q.

Cancer Res. 2008 Jul 15;68(14):5733-42. doi: 10.1158/0008-5472.CAN-08-0190.

12.

The Nf2 tumor suppressor, merlin, functions in Rac-dependent signaling.

Shaw RJ, Paez JG, Curto M, Yaktine A, Pruitt WM, Saotome I, O'Bryan JP, Gupta V, Ratner N, Der CJ, Jacks T, McClatchey AI.

Dev Cell. 2001 Jul;1(1):63-72.

13.

Identification and characterization of putative tumor suppressor NGB, a GTP-binding protein that interacts with the neurofibromatosis 2 protein.

Lee H, Kim D, Dan HC, Wu EL, Gritsko TM, Cao C, Nicosia SV, Golemis EA, Liu W, Coppola D, Brem SS, Testa JR, Cheng JQ.

Mol Cell Biol. 2007 Mar;27(6):2103-19. Epub 2007 Jan 8.

14.

Multistep phosphorylation by oncogenic kinases enhances the degradation of the NF2 tumor suppressor merlin.

Laulajainen M, Muranen T, Nyman TA, Carpén O, Grönholm M.

Neoplasia. 2011 Jul;13(7):643-52.

15.

Protein kinase A-mediated phosphorylation of the NF2 tumor suppressor protein merlin at serine 10 affects the actin cytoskeleton.

Laulajainen M, Muranen T, Carpén O, Grönholm M.

Oncogene. 2008 May 22;27(23):3233-43. Epub 2007 Dec 10.

PMID:
18071304
16.

NF2/Merlin mediates contact-dependent inhibition of EGFR mobility and internalization via cortical actomyosin.

Chiasson-MacKenzie C, Morris ZS, Baca Q, Morris B, Coker JK, Mirchev R, Jensen AE, Carey T, Stott SL, Golan DE, McClatchey AI.

J Cell Biol. 2015 Oct 26;211(2):391-405. doi: 10.1083/jcb.201503081. Epub 2015 Oct 19.

17.

The NF2 tumor suppressor, Merlin, regulates epidermal development through the establishment of a junctional polarity complex.

Gladden AB, Hebert AM, Schneeberger EE, McClatchey AI.

Dev Cell. 2010 Nov 16;19(5):727-39. doi: 10.1016/j.devcel.2010.10.008.

18.

Cyclic AMP-dependent protein kinase phosphorylates merlin at serine 518 independently of p21-activated kinase and promotes merlin-ezrin heterodimerization.

Alfthan K, Heiska L, Grönholm M, Renkema GH, Carpén O.

J Biol Chem. 2004 Apr 30;279(18):18559-66. Epub 2004 Feb 23.

19.

Role of Merlin/NF2 inactivation in tumor biology.

Petrilli AM, Fernández-Valle C.

Oncogene. 2016 Feb 4;35(5):537-48. doi: 10.1038/onc.2015.125. Epub 2015 Apr 20. Review.

20.

Phosphorylation of merlin regulates its stability and tumor suppressive activity.

Ye K.

Cell Adh Migr. 2007 Oct-Dec;1(4):196-8. Epub 2007 Oct 22. Review.

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