Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 73

1.

Synthesis and evaluation of antineurotoxicity properties of an amyloid-β peptide targeting ligand containing a triamino acid.

Honcharenko D, Bose PP, Maity J, Kurudenkandy FR, Juneja A, Flöistrup E, Biverstål H, Johansson J, Nilsson L, Fisahn A, Strömberg R.

Org Biomol Chem. 2014 Sep 14;12(34):6684-93. doi: 10.1039/c4ob00959b.

PMID:
25030615
2.

Amyloid-β-induced action potential desynchronization and degradation of hippocampal gamma oscillations is prevented by interference with peptide conformation change and aggregation.

Kurudenkandy FR, Zilberter M, Biverstål H, Presto J, Honcharenko D, Strömberg R, Johansson J, Winblad B, Fisahn A.

J Neurosci. 2014 Aug 20;34(34):11416-25. doi: 10.1523/JNEUROSCI.1195-14.2014.

3.

Alpha-helix targeting reduces amyloid-beta peptide toxicity.

Nerelius C, Sandegren A, Sargsyan H, Raunak R, Leijonmarck H, Chatterjee U, Fisahn A, Imarisio S, Lomas DA, Crowther DC, Strömberg R, Johansson J.

Proc Natl Acad Sci U S A. 2009 Jun 9;106(23):9191-6. doi: 10.1073/pnas.0810364106. Epub 2009 May 20.

4.

Location and conformation of amyloid β(25-35) peptide and its sequence-shuffled peptides within membranes: implications for aggregation and toxicity in PC12 cells.

Tsai HH, Lee JB, Shih YC, Wan L, Shieh FK, Chen CY.

ChemMedChem. 2014 May;9(5):1002-11. doi: 10.1002/cmdc.201400062. Epub 2014 Apr 11.

PMID:
24729535
5.

Effects of ligands on unfolding of the amyloid β-peptide central helix: mechanistic insights from molecular dynamics simulations.

Ito M, Johansson J, Strömberg R, Nilsson L.

PLoS One. 2012;7(1):e30510. doi: 10.1371/journal.pone.0030510. Epub 2012 Jan 23.

6.

Inhibition of amyloid-β aggregation in Alzheimer's disease.

Wang Q, Yu X, Li L, Zheng J.

Curr Pharm Des. 2014;20(8):1223-43. Review.

PMID:
23713775
7.

Benzophenone-based derivatives: a novel series of potent and selective dual inhibitors of acetylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation.

Belluti F, Bartolini M, Bottegoni G, Bisi A, Cavalli A, Andrisano V, Rampa A.

Eur J Med Chem. 2011 May;46(5):1682-93. doi: 10.1016/j.ejmech.2011.02.019. Epub 2011 Feb 22.

PMID:
21397996
8.

Molecular structure of the NQTrp inhibitor with the Alzheimer Aβ1-28 monomer.

Tarus B, Nguyen PH, Berthoumieu O, Faller P, Doig AJ, Derreumaux P.

Eur J Med Chem. 2015 Feb 16;91:43-50. doi: 10.1016/j.ejmech.2014.07.002. Epub 2014 Jul 1.

PMID:
25011560
9.

Inhibition of protein aggregation: supramolecular assemblies of arginine hold the key.

Das U, Hariprasad G, Ethayathulla AS, Manral P, Das TK, Pasha S, Mann A, Ganguli M, Verma AK, Bhat R, Chandrayan SK, Ahmed S, Sharma S, Kaur P, Singh TP, Srinivasan A.

PLoS One. 2007 Nov 14;2(11):e1176.

10.

Molecular dynamics simulations of Aβ fibril interactions with β-sheet breaker peptides.

Bruce NJ, Chen D, Dastidar SG, Marks GE, Schein CH, Bryce RA.

Peptides. 2010 Nov;31(11):2100-8. doi: 10.1016/j.peptides.2010.07.015. Epub 2010 Aug 4.

PMID:
20691234
11.

In silico investigation and targeting of amyloid β oligomers of different size.

Autiero I, Saviano M, Langella E.

Mol Biosyst. 2013 Aug;9(8):2118-24. doi: 10.1039/c3mb70086k. Epub 2013 May 24.

PMID:
23708585
12.

Conformational restriction via cyclization in beta-amyloid peptide Abeta(1-28) leads to an inhibitor of Abeta(1-28) amyloidogenesis and cytotoxicity.

Kapurniotu A, Buck A, Weber M, Schmauder A, Hirsch T, Bernhagen J, Tatarek-Nossol M.

Chem Biol. 2003 Feb;10(2):149-59.

13.

Effect of graphene oxide on the conformational transitions of amyloid beta peptide: A molecular dynamics simulation study.

Baweja L, Balamurugan K, Subramanian V, Dhawan A.

J Mol Graph Model. 2015 Sep;61:175-85. doi: 10.1016/j.jmgm.2015.07.007. Epub 2015 Jul 28.

PMID:
26275931
14.

Photo-induced inhibition of Alzheimer's β-amyloid aggregation in vitro by rose bengal.

Lee JS, Lee BI, Park CB.

Biomaterials. 2015 Jan;38:43-9. doi: 10.1016/j.biomaterials.2014.10.058. Epub 2014 Nov 11.

PMID:
25457982
15.

Structural basis for Aβ1–42 toxicity inhibition by Aβ C-terminal fragments: discrete molecular dynamics study.

Urbanc B, Betnel M, Cruz L, Li H, Fradinger EA, Monien BH, Bitan G.

J Mol Biol. 2011 Jul 8;410(2):316-28. doi: 10.1016/j.jmb.2011.05.021. Epub 2011 May 23.

16.

Perlecan domain V inhibits α2 integrin-mediated amyloid-β neurotoxicity.

Wright S, Parham C, Lee B, Clarke D, Auckland L, Johnston J, Lawrence AL, Dickeson SK, Santoro SA, Griswold-Prenner I, Bix G.

Neurobiol Aging. 2012 Jul;33(7):1379-88. doi: 10.1016/j.neurobiolaging.2010.10.018. Epub 2010 Dec 3.

PMID:
21126803
17.

Transthyretin-derived peptides as β-amyloid inhibitors.

Cho PY, Joshi G, Johnson JA, Murphy RM.

ACS Chem Neurosci. 2014 Jul 16;5(7):542-51. doi: 10.1021/cn500014u. Epub 2014 Apr 9.

18.

Inhibition of β-amyloid peptide self-assembly and cytotoxicity by poly(LVFF-co-β-amino ester).

Xie H, Qiao Z, Wang H, Duan H, Yang Y, Wang C.

J Pept Sci. 2015 Jul;21(7):608-14. doi: 10.1002/psc.2784. Epub 2015 Apr 30.

PMID:
25931322
19.

Structures of the amyloid β-peptides Aβ1-40 and Aβ1-42 as influenced by pH and a D-peptide.

Olubiyi OO, Strodel B.

J Phys Chem B. 2012 Mar 15;116(10):3280-91. doi: 10.1021/jp2076337. Epub 2012 Mar 1.

PMID:
22300010
20.

Heme prevents amyloid beta peptide aggregation through hydrophobic interaction based on molecular dynamics simulation.

Zhao LN, Mu Y, Chew LY.

Phys Chem Chem Phys. 2013 Sep 7;15(33):14098-106. doi: 10.1039/c3cp52354c. Epub 2013 Jul 18.

PMID:
23868536

Supplemental Content

Support Center