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Items: 1 to 20 of 103

1.

Regulation of oxidative stress by methylation-controlled J protein controls macrophage responses to inflammatory insults.

Navasa N, Martín I, Iglesias-Pedraz JM, Beraza N, Atondo E, Izadi H, Ayaz F, Fernández-Álvarez S, Hatle K, Som A, Dienz O, Osborne BA, Martínez-Chantar ML, Rincón M, Anguita J.

J Infect Dis. 2015 Jan 1;211(1):135-45. doi: 10.1093/infdis/jiu389. Epub 2014 Jul 14.

2.

MCJ/DnaJC15, an endogenous mitochondrial repressor of the respiratory chain that controls metabolic alterations.

Hatle KM, Gummadidala P, Navasa N, Bernardo E, Dodge J, Silverstrim B, Fortner K, Burg E, Suratt BT, Hammer J, Radermacher M, Taatjes DJ, Thornton T, Anguita J, Rincon M.

Mol Cell Biol. 2013 Jun;33(11):2302-14. doi: 10.1128/MCB.00189-13. Epub 2013 Mar 25.

3.

Fine-Tuning of CD8(+) T Cell Mitochondrial Metabolism by the Respiratory Chain Repressor MCJ Dictates Protection to Influenza Virus.

Champagne DP, Hatle KM, Fortner KA, D'Alessandro A, Thornton TM, Yang R, Torralba D, Tomás-Cortázar J, Jun YW, Ahn KH, Hansen KC, Haynes L, Anguita J, Rincon M.

Immunity. 2016 Jun 21;44(6):1299-311. doi: 10.1016/j.immuni.2016.02.018. Epub 2016 May 24.

4.

Ikaros mediates the DNA methylation-independent silencing of MCJ/DNAJC15 gene expression in macrophages.

Navasa N, Martin-Ruiz I, Atondo E, Sutherland JD, Angel Pascual-Itoiz M, Carreras-González A, Izadi H, Tomás-Cortázar J, Ayaz F, Martin-Martin N, Torres IM, Barrio R, Carracedo A, Olivera ER, Rincón M, Anguita J.

Sci Rep. 2015 Sep 30;5:14692. doi: 10.1038/srep14692.

5.

Methylation-controlled J-protein MCJ acts in the import of proteins into human mitochondria.

Schusdziarra C, Blamowska M, Azem A, Hell K.

Hum Mol Genet. 2013 Apr 1;22(7):1348-57. doi: 10.1093/hmg/dds541. Epub 2012 Dec 20.

PMID:
23263864
6.

Heme induces programmed necrosis on macrophages through autocrine TNF and ROS production.

Fortes GB, Alves LS, de Oliveira R, Dutra FF, Rodrigues D, Fernandez PL, Souto-Padron T, De Rosa MJ, Kelliher M, Golenbock D, Chan FK, Bozza MT.

Blood. 2012 Mar 8;119(10):2368-75. doi: 10.1182/blood-2011-08-375303. Epub 2012 Jan 18.

7.

Uncoupling lipid metabolism from inflammation through fatty acid binding protein-dependent expression of UCP2.

Xu H, Hertzel AV, Steen KA, Wang Q, Suttles J, Bernlohr DA.

Mol Cell Biol. 2015 Mar;35(6):1055-65. doi: 10.1128/MCB.01122-14. Epub 2015 Jan 12.

8.

TLR signalling augments macrophage bactericidal activity through mitochondrial ROS.

West AP, Brodsky IE, Rahner C, Woo DK, Erdjument-Bromage H, Tempst P, Walsh MC, Choi Y, Shadel GS, Ghosh S.

Nature. 2011 Apr 28;472(7344):476-80. doi: 10.1038/nature09973.

9.

Mitochondria contribute to LPS-induced MAPK activation via uncoupling protein UCP2 in macrophages.

Emre Y, Hurtaud C, Nübel T, Criscuolo F, Ricquier D, Cassard-Doulcier AM.

Biochem J. 2007 Mar 1;402(2):271-8.

10.

Mycobacterium avium MAV2052 protein induces apoptosis in murine macrophage cells through Toll-like receptor 4.

Lee KI, Choi HG, Son YJ, Whang J, Kim K, Jeon HS, Park HS, Back YW, Choi S, Kim SW, Choi CH, Kim HJ.

Apoptosis. 2016 Apr;21(4):459-72. doi: 10.1007/s10495-016-1220-y.

PMID:
26842846
11.
12.

A disintegrin and metalloproteinase 17 regulates TNF and TNFR1 levels in inflammation and liver regeneration in mice.

McMahan RS, Riehle KJ, Fausto N, Campbell JS.

Am J Physiol Gastrointest Liver Physiol. 2013 Jul 1;305(1):G25-34. doi: 10.1152/ajpgi.00326.2012. Epub 2013 May 2.

13.

Elevated mitochondrial reactive oxygen species generation affects the immune response via hypoxia-inducible factor-1alpha in long-lived Mclk1+/- mouse mutants.

Wang D, Malo D, Hekimi S.

J Immunol. 2010 Jan 15;184(2):582-90. doi: 10.4049/jimmunol.0902352. Epub 2009 Dec 9.

14.

Inflammasome activation by mitochondrial oxidative stress in macrophages leads to the development of angiotensin II-induced aortic aneurysm.

Usui F, Shirasuna K, Kimura H, Tatsumi K, Kawashima A, Karasawa T, Yoshimura K, Aoki H, Tsutsui H, Noda T, Sagara J, Taniguchi S, Takahashi M.

Arterioscler Thromb Vasc Biol. 2015 Jan;35(1):127-36. doi: 10.1161/ATVBAHA.114.303763. Epub 2014 Nov 6.

15.

Muscle immobilization and remobilization downregulates PGC-1α signaling and the mitochondrial biogenesis pathway.

Kang C, Ji LL.

J Appl Physiol (1985). 2013 Dec;115(11):1618-25. doi: 10.1152/japplphysiol.01354.2012. Epub 2013 Aug 22.

16.

Mitochondrial reactive oxygen species mediate GPCR-induced TACE/ADAM17-dependent transforming growth factor-alpha shedding.

Myers TJ, Brennaman LH, Stevenson M, Higashiyama S, Russell WE, Lee DC, Sunnarborg SW.

Mol Biol Cell. 2009 Dec;20(24):5236-49. doi: 10.1091/mbc.E08-12-1256.

17.

The inositol 3-phosphatase PTEN negatively regulates Fc gamma receptor signaling, but supports Toll-like receptor 4 signaling in murine peritoneal macrophages.

Cao X, Wei G, Fang H, Guo J, Weinstein M, Marsh CB, Ostrowski MC, Tridandapani S.

J Immunol. 2004 Apr 15;172(8):4851-7.

18.
19.

Angiotensin II induced proteolytic cleavage of myocardial ACE2 is mediated by TACE/ADAM-17: a positive feedback mechanism in the RAS.

Patel VB, Clarke N, Wang Z, Fan D, Parajuli N, Basu R, Putko B, Kassiri Z, Turner AJ, Oudit GY.

J Mol Cell Cardiol. 2014 Jan;66:167-76. doi: 10.1016/j.yjmcc.2013.11.017. Epub 2013 Dec 9.

PMID:
24332999
20.

Activation of TNFR1 ectodomain shedding by mitochondrial Ca2+ determines the severity of inflammation in mouse lung microvessels.

Rowlands DJ, Islam MN, Das SR, Huertas A, Quadri SK, Horiuchi K, Inamdar N, Emin MT, Lindert J, Ten VS, Bhattacharya S, Bhattacharya J.

J Clin Invest. 2011 May;121(5):1986-99. doi: 10.1172/JCI43839. Epub 2011 Apr 25.

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