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Items: 1 to 20 of 104

1.

Prolactin (PRL)-stimulated ubiquitination of ZnT2 mediates a transient increase in zinc secretion followed by ZnT2 degradation in mammary epithelial cells.

Seo YA, Lee S, Hennigar SR, Kelleher SL.

J Biol Chem. 2014 Aug 22;289(34):23653-61. doi: 10.1074/jbc.M113.531145.

2.

Prolactin regulates ZNT2 expression through the JAK2/STAT5 signaling pathway in mammary cells.

Qian L, Lopez V, Seo YA, Kelleher SL.

Am J Physiol Cell Physiol. 2009 Aug;297(2):C369-77. doi: 10.1152/ajpcell.00589.2008.

3.

Essential Role for Zinc Transporter 2 (ZnT2)-mediated Zinc Transport in Mammary Gland Development and Function during Lactation.

Lee S, Hennigar SR, Alam S, Nishida K, Kelleher SL.

J Biol Chem. 2015 May 22;290(21):13064-78. doi: 10.1074/jbc.M115.637439.

4.
5.

ZnT2 is a critical mediator of lysosomal-mediated cell death during early mammary gland involution.

Hennigar SR, Seo YA, Sharma S, Soybel DI, Kelleher SL.

Sci Rep. 2015 Jan 26;5:8033. doi: 10.1038/srep08033.

6.

Exome Sequencing of SLC30A2 Identifies Novel Loss- and Gain-of-Function Variants Associated with Breast Cell Dysfunction.

Alam S, Hennigar SR, Gallagher C, Soybel DI, Kelleher SL.

J Mammary Gland Biol Neoplasia. 2015 Dec;20(3-4):159-72. doi: 10.1007/s10911-015-9338-z. Erratum in: J Mammary Gland Biol Neoplasia. 2016 Dec;21(3-4):149.

PMID:
26293594
8.

Prolactin receptor attenuation induces zinc pool redistribution through ZnT2 and decreases invasion in MDA-MB-453 breast cancer cells.

Bostanci Z, Alam S, Soybel DI, Kelleher SL.

Exp Cell Res. 2014 Feb 15;321(2):190-200. doi: 10.1016/j.yexcr.2013.12.005.

PMID:
24333596
9.

A histidine-rich motif mediates mitochondrial localization of ZnT2 to modulate mitochondrial function.

Seo YA, Lopez V, Kelleher SL.

Am J Physiol Cell Physiol. 2011 Jun;300(6):C1479-89. doi: 10.1152/ajpcell.00420.2010.

10.

Mammary gland copper transport is stimulated by prolactin through alterations in Ctr1 and Atp7A localization.

Kelleher SL, Lönnerdal B.

Am J Physiol Regul Integr Comp Physiol. 2006 Oct;291(4):R1181-91.

11.

Prolactin-dependent activation of a tyrosine phosphorylated DNA binding factor in mouse mammary epithelial cells.

Welte T, Garimorth K, Philipp S, Doppler W.

Mol Endocrinol. 1994 Aug;8(8):1091-102.

PMID:
7527899
12.

TNFα Post-Translationally Targets ZnT2 to Accumulate Zinc in Lysosomes.

Hennigar SR, Kelleher SL.

J Cell Physiol. 2015 Oct;230(10):2345-50. doi: 10.1002/jcp.24992.

PMID:
25808614
13.

Zinc Finger Homeodomain Factor Zfhx3 Is Essential for Mammary Lactogenic Differentiation by Maintaining Prolactin Signaling Activity.

Zhao D, Ma G, Zhang X, He Y, Li M, Han X, Fu L, Dong XY, Nagy T, Zhao Q, Fu L, Dong JT.

J Biol Chem. 2016 Jun 10;291(24):12809-20. doi: 10.1074/jbc.M116.719377.

PMID:
27129249
14.

Prolactin negatively regulates caveolin-1 gene expression in the mammary gland during lactation, via a Ras-dependent mechanism.

Park DS, Lee H, Riedel C, Hulit J, Scherer PE, Pestell RG, Lisanti MP.

J Biol Chem. 2001 Dec 21;276(51):48389-97.

15.

Progesterone receptor repression of prolactin/signal transducer and activator of transcription 5-mediated transcription of the beta-casein gene in mammary epithelial cells.

Buser AC, Gass-Handel EK, Wyszomierski SL, Doppler W, Leonhardt SA, Schaack J, Rosen JM, Watkin H, Anderson SM, Edwards DP.

Mol Endocrinol. 2007 Jan;21(1):106-25.

PMID:
16973758
16.

STAT5-glucocorticoid receptor interaction and MTF-1 regulate the expression of ZnT2 (Slc30a2) in pancreatic acinar cells.

Guo L, Lichten LA, Ryu MS, Liuzzi JP, Wang F, Cousins RJ.

Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):2818-23. doi: 10.1073/pnas.0914941107.

17.

Functional analysis of two single nucleotide polymorphisms in SLC30A2 (ZnT2): implications for mammary gland function and breast disease in women.

Seo YA, Kelleher SL.

Physiol Genomics. 2010 Nov 29;42A(4):219-27. doi: 10.1152/physiolgenomics.00137.2010.

18.

ZnT2-overexpression represses the cytotoxic effects of zinc hyper-accumulation in malignant metallothionein-null T47D breast tumor cells.

Lopez V, Foolad F, Kelleher SL.

Cancer Lett. 2011 May 1;304(1):41-51. doi: 10.1016/j.canlet.2011.01.027.

PMID:
21353385
19.

Prolactin-mediated regulation of lipid biosynthesis genes in vivo in the lactating mammary epithelial cell.

Rudolph MC, Russell TD, Webb P, Neville MC, Anderson SM.

Am J Physiol Endocrinol Metab. 2011 Jun;300(6):E1059-68. doi: 10.1152/ajpendo.00083.2011.

20.

ZnT4 provides zinc to zinc-dependent proteins in the trans-Golgi network critical for cell function and Zn export in mammary epithelial cells.

McCormick NH, Kelleher SL.

Am J Physiol Cell Physiol. 2012 Aug 1;303(3):C291-7. doi: 10.1152/ajpcell.00443.2011.

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