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Exopolysaccharides synthesized by Lactobacillus reuteri protect against enterotoxigenic Escherichia coli in piglets.

Chen XY, Woodward A, Zijlstra RT, Gänzle MG.

Appl Environ Microbiol. 2014 Sep;80(18):5752-60. doi: 10.1128/AEM.01782-14. Epub 2014 Jul 11.


Casein glycomacropeptide in the diet may reduce Escherichia coli attachment to the intestinal mucosa and increase the intestinal lactobacilli of early weaned piglets after an enterotoxigenic E. coli K88 challenge.

Gustavo Hermes R, Molist F, Francisco Pérez J, Gómez de Segura A, Ywazaki M, Davin R, Nofrarías M, Korhonen TK, Virkola R, Martín-Orúe SM.

Br J Nutr. 2013 Mar 28;109(6):1001-12. doi: 10.1017/S0007114512002978. Epub 2012 Aug 1.


Feed Fermentation with Reuteran- and Levan-Producing Lactobacillus reuteri Reduces Colonization of Weanling Pigs by Enterotoxigenic Escherichia coli.

Yang Y, Galle S, Le MH, Zijlstra RT, Gänzle MG.

Appl Environ Microbiol. 2015 Sep 1;81(17):5743-52. doi: 10.1128/AEM.01525-15. Epub 2015 Jun 12.


Screening of extracts from natural feed ingredients for their ability to reduce enterotoxigenic Escherichia coli (ETEC) K88 adhesion to porcine intestinal epithelial cell-line IPEC-J2.

González-Ortiz G, Hermes RG, Jiménez-Díaz R, Pérez JF, Martín-Orúe SM.

Vet Microbiol. 2013 Dec 27;167(3-4):494-9. doi: 10.1016/j.vetmic.2013.07.035. Epub 2013 Aug 9.


Screening the ability of natural feed ingredients to interfere with the adherence of enterotoxigenic Escherichia coli (ETEC) K88 to the porcine intestinal mucus.

González-Ortiz G, Pérez JF, Hermes RG, Molist F, Jiménez-Díaz R, Martín-Orúe SM.

Br J Nutr. 2014 Feb;111(4):633-42. doi: 10.1017/S0007114513003024. Epub 2013 Sep 19.


Effect of Lactobacillus plantarum on diarrhea and intestinal barrier function of young piglets challenged with enterotoxigenic Escherichia coli K88.

Yang KM, Jiang ZY, Zheng CT, Wang L, Yang XF.

J Anim Sci. 2014 Apr;92(4):1496-503. doi: 10.2527/jas.2013-6619. Epub 2014 Feb 3.


Exopolysaccharide synthesized by Lactobacillus reuteri decreases the ability of enterotoxigenic Escherichia coli to bind to porcine erythrocytes.

Wang Y, Gänzle MG, Schwab C.

Appl Environ Microbiol. 2010 Jul;76(14):4863-6. doi: 10.1128/AEM.03137-09. Epub 2010 May 14.


Both enzymatic and non-enzymatic properties of heat-labile enterotoxin are responsible for LT-enhanced adherence of enterotoxigenic Escherichia coli to porcine IPEC-J2 cells.

Fekete PZ, Mateo KS, Zhang W, Moxley RA, Kaushik RS, Francis DH.

Vet Microbiol. 2013 Jun 28;164(3-4):330-5. doi: 10.1016/j.vetmic.2013.02.019. Epub 2013 Feb 28.


Enzymatic Synthesis and Purification of Galactosylated Chitosan Oligosaccharides Reducing Adhesion of Enterotoxigenic Escherichia coli K88.

Yan YL, Hu Y, Simpson DJ, Gänzle MG.

J Agric Food Chem. 2017 Jun 28;65(25):5142-5150. doi: 10.1021/acs.jafc.7b01741. Epub 2017 Jun 19.


Modulatory effects of vasoactive intestinal peptide on intestinal mucosal immunity and microbial community of weaned piglets challenged by an enterotoxigenic Escherichia coli (K88).

Xu C, Wang Y, Sun R, Qiao X, Shang X, Niu W.

PLoS One. 2014 Aug 7;9(8):e104183. doi: 10.1371/journal.pone.0104183. eCollection 2014.


In Vitro Evaluation of Swine-Derived Lactobacillus reuteri: Probiotic Properties and Effects on Intestinal Porcine Epithelial Cells Challenged with Enterotoxigenic Escherichia coli K88.

Wang Z, Wang L, Chen Z, Ma X, Yang X, Zhang J, Jiang Z.

J Microbiol Biotechnol. 2016 Jun 28;26(6):1018-25. doi: 10.4014/jmb.1510.10089.


Protection of piglets against enteric colibacillosis by intranasal immunization with K88ac (F4ac) fimbriae and heat labile enterotoxin of Escherichia coli.

Lin J, Mateo KS, Zhao M, Erickson AK, Garcia N, He D, Moxley RA, Francis DH.

Vet Microbiol. 2013 Mar 23;162(2-4):731-9. doi: 10.1016/j.vetmic.2012.09.025. Epub 2012 Oct 3.


Protective effects of Lactobacillus plantarum on epithelial barrier disruption caused by enterotoxigenic Escherichia coli in intestinal porcine epithelial cells.

Wu Y, Zhu C, Chen Z, Chen Z, Zhang W, Ma X, Wang L, Yang X, Jiang Z.

Vet Immunol Immunopathol. 2016 Apr;172:55-63. doi: 10.1016/j.vetimm.2016.03.005. Epub 2016 Mar 5.


A Selected Lactobacillus rhamnosus Strain Promotes EGFR-Independent Akt Activation in an Enterotoxigenic Escherichia coli K88-Infected IPEC-J2 Cell Model.

Zhang W, Zhu YH, Yang JC, Yang GY, Zhou D, Wang JF.

PLoS One. 2015 Apr 27;10(4):e0125717. doi: 10.1371/journal.pone.0125717. eCollection 2015.

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