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Items: 1 to 20 of 66

1.

Histone demethylase RBP2 induced by Helicobactor Pylori CagA participates in the malignant transformation of gastric epithelial cells.

Liang X, Zeng J, Wang L, Shen L, Li S, Ma L, Ci X, Yu J, Jia M, Sun Y, Liu Z, Liu S, Li W, Yu H, Chen C, Jia J.

Oncotarget. 2014 Jul 30;5(14):5798-807.

2.

Histone demethylase RBP2 promotes malignant progression of gastric cancer through TGF-β1-(p-Smad3)-RBP2-E-cadherin-Smad3 feedback circuit.

Liang X, Zeng J, Wang L, Shen L, Ma X, Li S, Wu Y, Ma L, Ci X, Guo Q, Jia M, Shen H, Sun Y, Liu Z, Liu S, Li W, Yu H, Chen C, Jia J.

Oncotarget. 2015 Jul 10;6(19):17661-74.

3.

Critical role of histone demethylase RBP2 in human gastric cancer angiogenesis.

Li L, Wang L, Song P, Geng X, Liang X, Zhou M, Wang Y, Chen C, Jia J, Zeng J.

Mol Cancer. 2014 Apr 9;13:81. doi: 10.1186/1476-4598-13-81.

4.

Spermine oxidase mediates the gastric cancer risk associated with Helicobacter pylori CagA.

Chaturvedi R, Asim M, Romero-Gallo J, Barry DP, Hoge S, de Sablet T, Delgado AG, Wroblewski LE, Piazuelo MB, Yan F, Israel DA, Casero RA Jr, Correa P, Gobert AP, Polk DB, Peek RM Jr, Wilson KT.

Gastroenterology. 2011 Nov;141(5):1696-708.e1-2. doi: 10.1053/j.gastro.2011.07.045. Epub 2011 Aug 10.

5.

The histone demethylase RBP2 Is overexpressed in gastric cancer and its inhibition triggers senescence of cancer cells.

Zeng J, Ge Z, Wang L, Li Q, Wang N, Björkholm M, Jia J, Xu D.

Gastroenterology. 2010 Mar;138(3):981-92. doi: 10.1053/j.gastro.2009.10.004. Epub 2009 Oct 20.

PMID:
19850045
6.

Helicobacter pylori CagA interacts with E-cadherin and deregulates the beta-catenin signal that promotes intestinal transdifferentiation in gastric epithelial cells.

Murata-Kamiya N, Kurashima Y, Teishikata Y, Yamahashi Y, Saito Y, Higashi H, Aburatani H, Akiyama T, Peek RM Jr, Azuma T, Hatakeyama M.

Oncogene. 2007 Jul 12;26(32):4617-26. Epub 2007 Jan 22.

PMID:
17237808
7.

Transgenic expression of Helicobacter pylori CagA induces gastrointestinal and hematopoietic neoplasms in mouse.

Ohnishi N, Yuasa H, Tanaka S, Sawa H, Miura M, Matsui A, Higashi H, Musashi M, Iwabuchi K, Suzuki M, Yamada G, Azuma T, Hatakeyama M.

Proc Natl Acad Sci U S A. 2008 Jan 22;105(3):1003-8. doi: 10.1073/pnas.0711183105. Epub 2008 Jan 11.

8.

Histone demethylase RBP2 promotes lung tumorigenesis and cancer metastasis.

Teng YC, Lee CF, Li YS, Chen YR, Hsiao PW, Chan MY, Lin FM, Huang HD, Chen YT, Jeng YM, Hsu CH, Yan Q, Tsai MD, Juan LJ.

Cancer Res. 2013 Aug 1;73(15):4711-21. doi: 10.1158/0008-5472.CAN-12-3165. Epub 2013 May 30.

9.

Helicobacter pylori CagA triggers expression of the bactericidal lectin REG3γ via gastric STAT3 activation.

Lee KS, Kalantzis A, Jackson CB, O'Connor L, Murata-Kamiya N, Hatakeyama M, Judd LM, Giraud AS, Menheniott TR.

PLoS One. 2012;7(2):e30786. doi: 10.1371/journal.pone.0030786. Epub 2012 Feb 1.

10.

The genome-wide expression profile of gastric epithelial cells infected by naturally occurring cagA isogenic strains of Helicobacter pylori.

Sohn SH, Lee YC.

Environ Toxicol Pharmacol. 2011 Nov;32(3):382-9. doi: 10.1016/j.etap.2011.08.006. Epub 2011 Aug 16.

PMID:
22004957
11.

Helicobacter pylori stimulates gastric epithelial cell MMP-1 secretion via CagA-dependent and -independent ERK activation.

Pillinger MH, Marjanovic N, Kim SY, Lee YC, Scher JU, Roper J, Abeles AM, Izmirly PI, Axelrod M, Pillinger MY, Tolani S, Dinsell V, Abramson SB, Blaser MJ.

J Biol Chem. 2007 Jun 29;282(26):18722-31. Epub 2007 May 2.

12.
13.

Stability of Helicobacter pylori CagA oncoprotein in human gastric epithelial cells.

Ishikawa S, Ohta T, Hatakeyama M.

FEBS Lett. 2009 Jul 21;583(14):2414-8. doi: 10.1016/j.febslet.2009.06.043. Epub 2009 Jun 26.

14.

Histone demethylase RBP2 is critical for breast cancer progression and metastasis.

Cao J, Liu Z, Cheung WK, Zhao M, Chen SY, Chan SW, Booth CJ, Nguyen DX, Yan Q.

Cell Rep. 2014 Mar 13;6(5):868-77. doi: 10.1016/j.celrep.2014.02.004. Epub 2014 Feb 27.

15.

The beta1 integrin activates JNK independent of CagA, and JNK activation is required for Helicobacter pylori CagA+-induced motility of gastric cancer cells.

Snider JL, Allison C, Bellaire BH, Ferrero RL, Cardelli JA.

J Biol Chem. 2008 May 16;283(20):13952-63. doi: 10.1074/jbc.M800289200. Epub 2008 Mar 20.

16.

Helicobacter pylori cytotoxin-associated gene A protein upregulates α-enolase expression via Src/MEK/ERK pathway: implication for progression of gastric cancer.

Chen S, Duan G, Zhang R, Fan Q.

Int J Oncol. 2014 Aug;45(2):764-70. doi: 10.3892/ijo.2014.2444. Epub 2014 May 19.

PMID:
24841372
17.

The CagA protein of Helicobacter pylori is translocated into epithelial cells and binds to SHP-2 in human gastric mucosa.

Yamazaki S, Yamakawa A, Ito Y, Ohtani M, Higashi H, Hatakeyama M, Azuma T.

J Infect Dis. 2003 Jan 15;187(2):334-7. Epub 2002 Dec 19.

PMID:
12552462
18.

Helicobacter pylori CagA protein targets the c-Met receptor and enhances the motogenic response.

Churin Y, Al-Ghoul L, Kepp O, Meyer TF, Birchmeier W, Naumann M.

J Cell Biol. 2003 Apr 28;161(2):249-55.

19.

Helicobacter pylori infection and CagA protein translocation in human primary gastric epithelial cell culture.

Lai YP, Yang JC, Lin TZ, Lin JT, Wang JT.

Helicobacter. 2006 Oct;11(5):451-9. Erratum in: Helicobacter. 2007 Jun;12(3):274.

PMID:
16961808
20.

Linking epithelial polarity and carcinogenesis by multitasking Helicobacter pylori virulence factor CagA.

Hatakeyama M.

Oncogene. 2008 Nov 24;27(55):7047-54. doi: 10.1038/onc.2008.353. Review.

PMID:
19029944

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