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A mathematical model of skeletal muscle disease and immune response in the mdx mouse.

Jarrah AS, Castiglione F, Evans NP, Grange RW, Laubenbacher R.

Biomed Res Int. 2014;2014:871810. doi: 10.1155/2014/871810.


Delayed bone regeneration is linked to chronic inflammation in murine muscular dystrophy.

Abou-Khalil R, Yang F, Mortreux M, Lieu S, Yu YY, Wurmser M, Pereira C, Relaix F, Miclau T, Marcucio RS, Colnot C.

J Bone Miner Res. 2014 Feb;29(2):304-15. doi: 10.1002/jbmr.2038.


Major basic protein-1 promotes fibrosis of dystrophic muscle and attenuates the cellular immune response in muscular dystrophy.

Wehling-Henricks M, Sokolow S, Lee JJ, Myung KH, Villalta SA, Tidball JG.

Hum Mol Genet. 2008 Aug 1;17(15):2280-92. doi: 10.1093/hmg/ddn129.


Rapamycin ameliorates dystrophic phenotype in mdx mouse skeletal muscle.

Eghtesad S, Jhunjhunwala S, Little SR, Clemens PR.

Mol Med. 2011 Sep-Oct;17(9-10):917-24. doi: 10.2119/molmed.2010.00256.


T and B lymphocyte depletion has a marked effect on the fibrosis of dystrophic skeletal muscles in the scid/mdx mouse.

Farini A, Meregalli M, Belicchi M, Battistelli M, Parolini D, D'Antona G, Gavina M, Ottoboni L, Constantin G, Bottinelli R, Torrente Y.

J Pathol. 2007 Oct;213(2):229-38.


Levels of α7 integrin and laminin-α2 are increased following prednisone treatment in the mdx mouse and GRMD dog models of Duchenne muscular dystrophy.

Wuebbles RD, Sarathy A, Kornegay JN, Burkin DJ.

Dis Model Mech. 2013 Sep;6(5):1175-84. doi: 10.1242/dmm.012211.


Mdx mice inducibly expressing dystrophin provide insights into the potential of gene therapy for duchenne muscular dystrophy.

Ahmad A, Brinson M, Hodges BL, Chamberlain JS, Amalfitano A.

Hum Mol Genet. 2000 Oct 12;9(17):2507-15.


Non-invasive MRI and spectroscopy of mdx mice reveal temporal changes in dystrophic muscle imaging and in energy deficits.

Heier CR, Guerron AD, Korotcov A, Lin S, Gordish-Dressman H, Fricke S, Sze RW, Hoffman EP, Wang P, Nagaraju K.

PLoS One. 2014 Nov 12;9(11):e112477. doi: 10.1371/journal.pone.0112477.


Myotonic ADR-MDX mutant mice show less severe muscular dystrophy than MDX mice.

Krämer R, Lochmüller H, Abicht A, Rüdel R, Brinkmeier H.

Neuromuscul Disord. 1998 Dec;8(8):542-50.


Enhanced expression of the alpha 7 beta 1 integrin reduces muscular dystrophy and restores viability in dystrophic mice.

Burkin DJ, Wallace GQ, Nicol KJ, Kaufman DJ, Kaufman SJ.

J Cell Biol. 2001 Mar 19;152(6):1207-18.


Skeletal muscle fibrosis in the mdx/utrn+/- mouse validates its suitability as a murine model of Duchenne muscular dystrophy.

Gutpell KM, Hrinivich WT, Hoffman LM.

PLoS One. 2015 Jan 21;10(1):e0117306. doi: 10.1371/journal.pone.0117306.


Effects of fish oil containing eicosapentaenoic acid and docosahexaenoic acid on dystrophic mdx mice.

Fogagnolo Mauricio A, Minatel E, Santo Neto H, Marques MJ.

Clin Nutr. 2013 Aug;32(4):636-42. doi: 10.1016/j.clnu.2012.11.013.


Exclusive skeletal muscle correction does not modulate dystrophic heart disease in the aged mdx model of Duchenne cardiomyopathy.

Wasala NB, Bostick B, Yue Y, Duan D.

Hum Mol Genet. 2013 Jul 1;22(13):2634-41. doi: 10.1093/hmg/ddt112.


Divergent impact of Toll-like receptor 2 deficiency on repair mechanisms in healthy muscle versus Duchenne muscular dystrophy.

Mojumdar K, Giordano C, Lemaire C, Liang F, Divangahi M, Qureshi ST, Petrof BJ.

J Pathol. 2016 May;239(1):10-22. doi: 10.1002/path.4689.


Helper (CD4(+)) and cytotoxic (CD8(+)) T cells promote the pathology of dystrophin-deficient muscle.

Spencer MJ, Montecino-Rodriguez E, Dorshkind K, Tidball JG.

Clin Immunol. 2001 Feb;98(2):235-43.


Taurine deficiency, synthesis and transport in the mdx mouse model for Duchenne Muscular Dystrophy.

Terrill JR, Grounds MD, Arthur PG.

Int J Biochem Cell Biol. 2015 Sep;66:141-8. doi: 10.1016/j.biocel.2015.07.016.


Long-Term Therapy With Omega-3 Ameliorates Myonecrosis and Benefits Skeletal Muscle Regeneration in Mdx Mice.

Apolinário LM, De Carvalho SC, Santo Neto H, Marques MJ.

Anat Rec (Hoboken). 2015 Sep;298(9):1589-96. doi: 10.1002/ar.23177.


Increased levels of interleukin-6 exacerbate the dystrophic phenotype in mdx mice.

Pelosi L, Berardinelli MG, Forcina L, Spelta E, Rizzuto E, Nicoletti C, Camilli C, Testa E, Catizone A, De Benedetti F, Musarò A.

Hum Mol Genet. 2015 Nov 1;24(21):6041-53. doi: 10.1093/hmg/ddv323.


Distinct roles of TRAF6 at early and late stages of muscle pathology in the mdx model of Duchenne muscular dystrophy.

Hindi SM, Sato S, Choi Y, Kumar A.

Hum Mol Genet. 2014 Mar 15;23(6):1492-505. doi: 10.1093/hmg/ddt536.


IFN-γ promotes muscle damage in the mdx mouse model of Duchenne muscular dystrophy by suppressing M2 macrophage activation and inhibiting muscle cell proliferation.

Villalta SA, Deng B, Rinaldi C, Wehling-Henricks M, Tidball JG.

J Immunol. 2011 Nov 15;187(10):5419-28. doi: 10.4049/jimmunol.1101267.

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