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Items: 1 to 20 of 199

1.

Chinese prescription Kangen-karyu and Salviae Miltiorrhizae Radix improve age-related oxidative stress and inflammatory response through the PI3K/Akt or MAPK pathways.

Park CH, Kim DH, Park MH, Kim MK, Kim ND, Kim CM, Tanaka T, Yokozawa T, Chung HY, Moon HR.

Am J Chin Med. 2014;42(4):987-1005. doi: 10.1142/S0192415X14500621.

PMID:
25004887
3.
4.

Effects of the Chinese prescription Kangen-karyu and its crude drug Tanjin on ageing process in rats.

Yokozawa T, Cho EJ, Okamoto T, Sei Y.

J Pharm Pharmacol. 2006 Dec;58(12):1591-9.

PMID:
17331322
5.

Magnesium Lithospermate B from Salvia miltiorrhiza Bunge Ameliorates Aging-Induced Renal Inflammation and Senescence via NADPH Oxidase-Mediated Reactive Oxygen Generation.

Park CH, Shin SH, Lee EK, Kim DH, Kim MJ, Roh SS, Yokozawa T, Chung HY.

Phytother Res. 2017 May;31(5):721-728. doi: 10.1002/ptr.5789. Epub 2017 Feb 16.

PMID:
28211114
6.

Hepato-/reno-protective activity of Chinese prescription Kangen-karyu through inhibition of AGE formation and fibrosis-related protein expression in type 2 diabetes.

Okamoto T, Park CH, Noh JS, Toriizuka K, Sei Y, Park JC, Yokozawa T.

J Pharm Pharmacol. 2011 Jul;63(7):952-9. doi: 10.1111/j.2042-7158.2011.01299.x.

PMID:
21635261
7.

The protective role of Kangen-karyu against fructose-induced metabolic syndrome in a rat model.

Yokozawa T, Kim HJ, Yamabe N, Okamoto T, Cho EJ.

J Pharm Pharmacol. 2007 Sep;59(9):1271-8.

PMID:
17883899
8.
9.
10.

Scientific evidence for therapeutic effects of Chinese prescription Kangen-karyu from pre-clinical animal experiments.

Yokozawa T, Park CH, Matsumoto K.

Drug Discov Ther. 2017 Mar 22;11(1):6-14. doi: 10.5582/ddt.2016.01069. Epub 2017 Jan 26. Review.

11.

Protective effect of the Chinese prescription Kangen-karyu against high glucose-induced oxidative stress in LLC-PK1 cells.

Yokozawa T, Kim YA, Kim HY, Okamoto T, Sei Y.

J Ethnopharmacol. 2007 Jan 3;109(1):113-20. Epub 2006 Jul 22.

PMID:
16949779
12.

Therapeutic efficacy of Kangen-karyu against H2O2-induced premature senescence.

Cho EJ, Okamoto T, Yokozawa T.

J Pharm Pharmacol. 2008 Nov;60(11):1537-44. doi: 10.1211/jpp/60.11.0016.

PMID:
18957176
13.

The mechanisms underlying the anti-aging activity of the Chinese prescription Kangen-karyu in hydrogen peroxide-induced human fibroblasts.

Satoh A, Yokozawa T, Kim YA, Cho EJ, Okamoto T, Sei Y.

J Pharm Pharmacol. 2005 Oct;57(10):1335-43.

PMID:
16259763
14.

Effect of Chinese prescription Kangen-karyu on lipid metabolism in type 2 diabetic db/db mice.

Yamabe N, Kim HY, Kang KS, Zhao Q, Matsumoto K, Yokozawa T.

J Ethnopharmacol. 2010 Jun 16;129(3):299-305. doi: 10.1016/j.jep.2010.03.032. Epub 2010 Apr 2.

PMID:
20363309
15.

Evaluation of Effects of Chinese Prescription Kangen-karyu on Diabetes-Induced Alterations such as Oxidative Stress and Apoptosis in the Liver of Type 2 Diabetic db/db Mice.

Park CH, Noh JS, Okamoto T, Park JC, Yokozawa T.

Evid Based Complement Alternat Med. 2012;2012:143489. doi: 10.1155/2012/143489. Epub 2012 Aug 30.

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17.

Huangkui capsule attenuates renal fibrosis in diabetic nephropathy rats through regulating oxidative stress and p38MAPK/Akt pathways, compared to α-lipoic acid.

Mao ZM, Shen SM, Wan YG, Sun W, Chen HL, Huang MM, Yang JJ, Wu W, Tang HT, Tang RM.

J Ethnopharmacol. 2015 Sep 15;173:256-65. doi: 10.1016/j.jep.2015.07.036. Epub 2015 Jul 28.

PMID:
26226437
18.

The protective role of Chinese prescription Kangen-karyu extract on diet-induced hypercholesterolemia in rats.

Yokozawa T, Cho EJ, Sasaki S, Satoh A, Okamoto T, Sei Y.

Biol Pharm Bull. 2006 Apr;29(4):760-5.

19.

Quercetin disrupts tyrosine-phosphorylated phosphatidylinositol 3-kinase and myeloid differentiation factor-88 association, and inhibits MAPK/AP-1 and IKK/NF-κB-induced inflammatory mediators production in RAW 264.7 cells.

Endale M, Park SC, Kim S, Kim SH, Yang Y, Cho JY, Rhee MH.

Immunobiology. 2013 Dec;218(12):1452-67. doi: 10.1016/j.imbio.2013.04.019. Epub 2013 May 9.

PMID:
23735482
20.

Paeonol and danshensu combination attenuates apoptosis in myocardial infarcted rats by inhibiting oxidative stress: Roles of Nrf2/HO-1 and PI3K/Akt pathway.

Li H, Song F, Duan LR, Sheng JJ, Xie YH, Yang Q, Chen Y, Dong QQ, Zhang BL, Wang SW.

Sci Rep. 2016 Mar 29;6:23693. doi: 10.1038/srep23693.

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