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The magnolia bioactive constituent 4-O-methylhonokiol protects against high-fat diet-induced obesity and systemic insulin resistance in mice.

Zhang Z, Chen J, Jiang X, Wang J, Yan X, Zheng Y, Conklin DJ, Kim KS, Kim KH, Tan Y, Kim YH, Cai L.

Oxid Med Cell Longev. 2014;2014:965954. doi: 10.1155/2014/965954. Epub 2014 May 29.


Magnolia bioactive constituent 4-O-methylhonokiol prevents the impairment of cardiac insulin signaling and the cardiac pathogenesis in high-fat diet-induced obese mice.

Zhang Z, Chen J, Zhou S, Wang S, Cai X, Conklin DJ, Kim KS, Kim KH, Tan Y, Zheng Y, Kim YH, Cai L.

Int J Biol Sci. 2015 Jun 5;11(8):879-91. doi: 10.7150/ijbs.12101. eCollection 2015 Jun 5.


Magnolia extract (BL153) protection of heart from lipid accumulation caused cardiac oxidative damage, inflammation, and cell death in high-fat diet fed mice.

Sun W, Zhang Z, Chen Q, Yin X, Fu Y, Zheng Y, Cai L, Kim KS, Kim KH, Tan Y, Kim YH.

Oxid Med Cell Longev. 2014;2014:205849. doi: 10.1155/2014/205849. Epub 2014 Feb 16.


Protective Effects of 2-Dodecyl-6-Methoxycyclohexa-2,5 -Diene-1,4-Dione Isolated from Averrhoa Carambola L. (Oxalidaceae) Roots on High-Fat Diet-Induced Obesity and Insulin Resistance in Mice.

Li J, Wei X, Xie Q, Hoa Pham TT, Wei J, He P, Jiao Y, Xu X, Giang Nguyen TH, Wen Q, Huang R.

Cell Physiol Biochem. 2016;40(5):993-1004. Epub 2016 Dec 7.


Long-term supplementation of honokiol and magnolol ameliorates body fat accumulation, insulin resistance, and adipose inflammation in high-fat fed mice.

Kim YJ, Choi MS, Cha BY, Woo JT, Park YB, Kim SR, Jung UJ.

Mol Nutr Food Res. 2013 Nov;57(11):1988-98. doi: 10.1002/mnfr.201300113. Epub 2013 Jul 31.


BL153 partially prevents high-fat diet induced liver damage probably via inhibition of lipid accumulation, inflammation, and oxidative stress.

Wang J, Zhang C, Zhang Z, Chen Q, Lu X, Shao M, Chen L, Yang H, Zhang F, Cheng P, Tan Y, Kim KS, Kim KH, Wang B, Kim YH.

Oxid Med Cell Longev. 2014;2014:674690. doi: 10.1155/2014/674690. Epub 2014 Apr 3.


Garcinia Cambogia attenuates diet-induced adiposity but exacerbates hepatic collagen accumulation and inflammation.

Kim YJ, Choi MS, Park YB, Kim SR, Lee MK, Jung UJ.

World J Gastroenterol. 2013 Aug 7;19(29):4689-701. doi: 10.3748/wjg.v19.i29.4689.


Combined effects of rosiglitazone and conjugated linoleic acid on adiposity, insulin sensitivity, and hepatic steatosis in high-fat-fed mice.

Liu LF, Purushotham A, Wendel AA, Belury MA.

Am J Physiol Gastrointest Liver Physiol. 2007 Jun;292(6):G1671-82. Epub 2007 Feb 22.


Anti-obesity effects of boiled tuna extract in mice with obesity induced by a high-fat diet.

Kim Y, Kwon MJ, Choi JW, Lee MK, Kim C, Jung J, Aprianita H, Nam H, Nam TJ.

Int J Mol Med. 2016 Oct;38(4):1281-8. doi: 10.3892/ijmm.2016.2695. Epub 2016 Aug 1.


Magnolia extract (BL153) ameliorates kidney damage in a high fat diet-induced obesity mouse model.

Cui W, Wang Y, Chen Q, Sun W, Cai L, Tan Y, Kim KS, Kim KH, Kim YH.

Oxid Med Cell Longev. 2013;2013:367040. doi: 10.1155/2013/367040. Epub 2013 Nov 28.


Effect of chronic p,p'-dichlorodiphenyldichloroethylene (DDE) exposure on high fat diet-induced alterations in glucose and lipid metabolism in male C57BL/6H mice.

Howell GE 3rd, Mulligan C, Meek E, Chambers JE.

Toxicology. 2015 Feb 3;328:112-22. doi: 10.1016/j.tox.2014.12.017. Epub 2014 Dec 23.


Differential effects of low-dose resveratrol on adiposity and hepatic steatosis in diet-induced obese mice.

Cho SJ, Jung UJ, Choi MS.

Br J Nutr. 2012 Dec 28;108(12):2166-75. doi: 10.1017/S0007114512000347. Epub 2012 Mar 14.


The hepatoprotective effect of the combination use of Fructus Schisandrae with statin--A preclinical evaluation.

Wat E, Ng CF, Wong EC, Koon CM, Lau CP, Cheung DW, Fung KP, Lau CB, Leung PC.

J Ethnopharmacol. 2016 Feb 3;178:104-14. doi: 10.1016/j.jep.2015.12.004. Epub 2015 Dec 5.


High-fat diet-induced adiposity, adipose inflammation, hepatic steatosis and hyperinsulinemia in outbred CD-1 mice.

Gao M, Ma Y, Liu D.

PLoS One. 2015 Mar 13;10(3):e0119784. doi: 10.1371/journal.pone.0119784. eCollection 2015 Mar 13.


Metformin ameliorates hepatic steatosis and inflammation without altering adipose phenotype in diet-induced obesity.

Woo SL, Xu H, Li H, Zhao Y, Hu X, Zhao J, Guo X, Guo T, Botchlett R, Qi T, Pei Y, Zheng J, Xu Y, An X, Chen L, Chen L, Li Q, Xiao X, Huo Y, Wu C.

PLoS One. 2014 Mar 17;9(3):e91111. doi: 10.1371/journal.pone.0091111. eCollection 2014 Mar 17.


Dietary leucine--an environmental modifier of insulin resistance acting on multiple levels of metabolism.

Macotela Y, Emanuelli B, Bång AM, Espinoza DO, Boucher J, Beebe K, Gall W, Kahn CR.

PLoS One. 2011;6(6):e21187. doi: 10.1371/journal.pone.0021187. Epub 2011 Jun 22.


Effects of sitagliptin on nonalcoholic fatty liver disease in diet-induced obese rats.

Akaslan SB, Degertekin CK, Yilmaz G, Cakir N, Arslan M, Toruner FB.

Metab Syndr Relat Disord. 2013 Aug;11(4):243-50. doi: 10.1089/met.2012.0128. Epub 2013 Apr 1.


Supplementation of SK1 from Platycodi radix ameliorates obesity and glucose intolerance in mice fed a high-fat diet.

Kim JY, Moon KD, Seo KI, Park KW, Choi MS, Do GM, Jeong YK, Cho YS, Lee MK.

J Med Food. 2009 Jun;12(3):629-36. doi: 10.1089/jmf.2008.1234.


Dietary capsaicin reduces obesity-induced insulin resistance and hepatic steatosis in obese mice fed a high-fat diet.

Kang JH, Goto T, Han IS, Kawada T, Kim YM, Yu R.

Obesity (Silver Spring). 2010 Apr;18(4):780-7. doi: 10.1038/oby.2009.301. Epub 2009 Oct 1.


Levocetirizine ameliorates high fructose diet-induced insulin resistance, vascular dysfunction and hepatic steatosis in rats.

Shawky NM, Shehatou GS, Abdel Rahim M, Suddek GM, Gameil NM.

Eur J Pharmacol. 2014 Oct 5;740:353-63. doi: 10.1016/j.ejphar.2014.07.021. Epub 2014 Jul 24.


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