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Items: 1 to 20 of 76

1.

The vestigial enzyme D-dopachrome tautomerase protects the heart against ischemic injury.

Qi D, Atsina K, Qu L, Hu X, Wu X, Xu B, Piecychna M, Leng L, Fingerle-Rowson G, Zhang J, Bucala R, Young LH.

J Clin Invest. 2014 Aug;124(8):3540-50. doi: 10.1172/JCI73061. Epub 2014 Jul 1.

2.

Cardiac macrophage migration inhibitory factor inhibits JNK pathway activation and injury during ischemia/reperfusion.

Qi D, Hu X, Wu X, Merk M, Leng L, Bucala R, Young LH.

J Clin Invest. 2009 Dec;119(12):3807-16. doi: 10.1172/JCI39738. Epub 2009 Nov 16.

3.

Compartmentalized protective and detrimental effects of endogenous macrophage migration-inhibitory factor mediated by CXCR2 in a mouse model of myocardial ischemia/reperfusion.

Liehn EA, Kanzler I, Konschalla S, Kroh A, Simsekyilmaz S, Sönmez TT, Bucala R, Bernhagen J, Weber C.

Arterioscler Thromb Vasc Biol. 2013 Sep;33(9):2180-6. doi: 10.1161/ATVBAHA.113.301633. Epub 2013 Jul 18.

4.

Impaired macrophage migration inhibitory factor-AMP-activated protein kinase activation and ischemic recovery in the senescent heart.

Ma H, Wang J, Thomas DP, Tong C, Leng L, Wang W, Merk M, Zierow S, Bernhagen J, Ren J, Bucala R, Li J.

Circulation. 2010 Jul 20;122(3):282-92. doi: 10.1161/CIRCULATIONAHA.110.953208. Epub 2010 Jul 6.

5.

Limiting cardiac ischemic injury by pharmacological augmentation of macrophage migration inhibitory factor-AMP-activated protein kinase signal transduction.

Wang J, Tong C, Yan X, Yeung E, Gandavadi S, Hare AA, Du X, Chen Y, Xiong H, Ma C, Leng L, Young LH, Jorgensen WL, Li J, Bucala R.

Circulation. 2013 Jul 16;128(3):225-36. doi: 10.1161/CIRCULATIONAHA.112.000862. Epub 2013 Jun 10.

6.

Deficiency in TLR4 signal transduction ameliorates cardiac injury and cardiomyocyte contractile dysfunction during ischemia.

Zhao P, Wang J, He L, Ma H, Zhang X, Zhu X, Dolence EK, Ren J, Li J.

J Cell Mol Med. 2009 Aug;13(8A):1513-25. doi: 10.1111/j.1582-4934.2009.00798.x. Epub 2009 Jun 5.

7.

Activated protein C protects against myocardial ischemic/reperfusion injury through AMP-activated protein kinase signaling.

Wang J, Yang L, Rezaie AR, Li J.

J Thromb Haemost. 2011 Jul;9(7):1308-17. doi: 10.1111/j.1538-7836.2011.04331.x.

8.

The AMPK Agonist PT1 and mTOR Inhibitor 3HOI-BA-01 Protect Cardiomyocytes After Ischemia Through Induction of Autophagy.

Huang L, Dai K, Chen M, Zhou W, Wang X, Chen J, Zhou W.

J Cardiovasc Pharmacol Ther. 2016 Jan;21(1):70-81. doi: 10.1177/1074248415581177. Epub 2015 Apr 13.

PMID:
25868658
9.

Urocortin 2 autocrine/paracrine and pharmacologic effects to activate AMP-activated protein kinase in the heart.

Li J, Qi D, Cheng H, Hu X, Miller EJ, Wu X, Russell KS, Mikush N, Zhang J, Xiao L, Sherwin RS, Young LH.

Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):16133-8. doi: 10.1073/pnas.1312775110. Epub 2013 Sep 16.

10.

CTRP9 protein protects against myocardial injury following ischemia-reperfusion through AMP-activated protein kinase (AMPK)-dependent mechanism.

Kambara T, Ohashi K, Shibata R, Ogura Y, Maruyama S, Enomoto T, Uemura Y, Shimizu Y, Yuasa D, Matsuo K, Miyabe M, Kataoka Y, Murohara T, Ouchi N.

J Biol Chem. 2012 Jun 1;287(23):18965-73. doi: 10.1074/jbc.M112.357939. Epub 2012 Apr 18.

11.

Macrophage migration inhibitory factor provides cardioprotection during ischemia/reperfusion by reducing oxidative stress.

Koga K, Kenessey A, Powell SR, Sison CP, Miller EJ, Ojamaa K.

Antioxid Redox Signal. 2011 Apr 1;14(7):1191-202. doi: 10.1089/ars.2010.3163. Epub 2011 Feb 5.

PMID:
20831446
12.

The action of D-dopachrome tautomerase as an adipokine in adipocyte lipid metabolism.

Iwata T, Taniguchi H, Kuwajima M, Taniguchi T, Okuda Y, Sukeno A, Ishimoto K, Mizusawa N, Yoshimoto K.

PLoS One. 2012;7(3):e33402. doi: 10.1371/journal.pone.0033402. Epub 2012 Mar 12.

13.

Sestrin2 promotes LKB1-mediated AMPK activation in the ischemic heart.

Morrison A, Chen L, Wang J, Zhang M, Yang H, Ma Y, Budanov A, Lee JH, Karin M, Li J.

FASEB J. 2015 Feb;29(2):408-17. doi: 10.1096/fj.14-258814. Epub 2014 Nov 3.

14.

The AMPK/mTOR pathway is involved in D-dopachrome tautomerase gene transcription in adipocytes differentiated from SGBS cells, a human preadipocyte cell line.

Iwata T, Kuribayashi K, Nakasono M, Saito-Tarashima N, Minakawa N, Mizusawa N, Kido R, Yoshimoto K.

Cytokine. 2017 Aug;96:195-202. doi: 10.1016/j.cyto.2017.04.017. Epub 2017 Apr 25.

PMID:
28445821
15.

Targeted intracellular accumulation of macrophage migration inhibitory factor in the reperfused heart mediates cardioprotection.

Pohl J, Hendgen-Cotta UB, Rammos C, Luedike P, Mull E, Stoppe C, Jülicher K, Lue H, Merx MW, Kelm M, Bernhagen J, Rassaf T.

Thromb Haemost. 2016 Jan;115(1):200-12. doi: 10.1160/TH15-05-0436. Epub 2015 Aug 27.

PMID:
26310191
16.

NAD(+)-dependent SIRT1 deactivation has a key role on ischemia-reperfusion-induced apoptosis.

Cattelan A, Ceolotto G, Bova S, Albiero M, Kuppusamy M, De Martin S, Semplicini A, Fadini GP, de Kreutzenberg SV, Avogaro A.

Vascul Pharmacol. 2015 Jul;70:35-44. doi: 10.1016/j.vph.2015.02.004. Epub 2015 Apr 9.

PMID:
25863291
17.

The transforming growth factor-beta superfamily member growth-differentiation factor-15 protects the heart from ischemia/reperfusion injury.

Kempf T, Eden M, Strelau J, Naguib M, Willenbockel C, Tongers J, Heineke J, Kotlarz D, Xu J, Molkentin JD, Niessen HW, Drexler H, Wollert KC.

Circ Res. 2006 Feb 17;98(3):351-60. Epub 2006 Jan 5.

18.

Macrophage migration inhibitory factor stimulates AMP-activated protein kinase in the ischaemic heart.

Miller EJ, Li J, Leng L, McDonald C, Atsumi T, Bucala R, Young LH.

Nature. 2008 Jan 31;451(7178):578-82. doi: 10.1038/nature06504.

PMID:
18235500
19.

Cardiac Sirt1 mediates the cardioprotective effect of caloric restriction by suppressing local complement system activation after ischemia-reperfusion.

Yamamoto T, Tamaki K, Shirakawa K, Ito K, Yan X, Katsumata Y, Anzai A, Matsuhashi T, Endo J, Inaba T, Tsubota K, Sano M, Fukuda K, Shinmura K.

Am J Physiol Heart Circ Physiol. 2016 Apr 15;310(8):H1003-14. doi: 10.1152/ajpheart.00676.2015. Epub 2016 Feb 12.

20.

Interferon regulatory factor 9 is an essential mediator of heart dysfunction and cell death following myocardial ischemia/reperfusion injury.

Zhang Y, Liu X, She ZG, Jiang DS, Wan N, Xia H, Zhu XH, Wei X, Zhang XD, Li H.

Basic Res Cardiol. 2014;109(5):434. doi: 10.1007/s00395-014-0434-9. Epub 2014 Aug 24.

PMID:
25150882

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