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Items: 1 to 20 of 93


Autologous protein solution prepared from the blood of osteoarthritic patients contains an enhanced profile of anti-inflammatory cytokines and anabolic growth factors.

O'Shaughnessey K, Matuska A, Hoeppner J, Farr J, Klaassen M, Kaeding C, Lattermann C, King W, Woodell-May J.

J Orthop Res. 2014 Oct;32(10):1349-55. doi: 10.1002/jor.22671. Epub 2014 Jul 1.


Autologous protein solution inhibits MMP-13 production by IL-1β and TNFα-stimulated human articular chondrocytes.

Woodell-May J, Matuska A, Oyster M, Welch Z, O'Shaughnessey K, Hoeppner J.

J Orthop Res. 2011 Sep;29(9):1320-6. doi: 10.1002/jor.21384. Epub 2011 Mar 15.


White blood cell concentration correlates with increased concentrations of IL-1ra and improvement in WOMAC pain scores in an open-label safety study of autologous protein solution.

King W, van der Weegen W, Van Drumpt R, Soons H, Toler K, Woodell-May J.

J Exp Orthop. 2016 Dec;3(1):9. doi: 10.1186/s40634-016-0043-7. Epub 2016 Feb 9.


Blood-derived anti-inflammatory protein solution blocks the effect of IL-1β on human macrophages in vitro.

O'Shaughnessey KM, Panitch A, Woodell-May JE.

Inflamm Res. 2011 Oct;60(10):929-36. doi: 10.1007/s00011-011-0353-2. Epub 2011 Jun 18.


Autologous solution protects bovine cartilage explants from IL-1α- and TNFα-induced cartilage degradation.

Matuska A, O'shaughnessey K, King W, Woodell-May J.

J Orthop Res. 2013 Dec;31(12):1929-35. doi: 10.1002/jor.22464. Epub 2013 Aug 21.


Human blood-based anti-inflammatory solution inhibits osteoarthritis progression in a meniscal-tear rat study.

King W, Bendele A, Marohl T, Woodell-May J.

J Orthop Res. 2017 Oct;35(10):2260-2268. doi: 10.1002/jor.23528. Epub 2017 Mar 23.


Autologous conditioned serum: the comparative cytokine profiles of two commercial methods (IRAP and IRAP II) using equine blood.

Hraha TH, Doremus KM, McIlwraith CW, Frisbie DD.

Equine Vet J. 2011 Sep;43(5):516-21. doi: 10.1111/j.2042-3306.2010.00321.x. Epub 2011 Mar 11.


The anti-inflammatory and matrix restorative mechanisms of platelet-rich plasma in osteoarthritis.

Sundman EA, Cole BJ, Karas V, Della Valle C, Tetreault MW, Mohammed HO, Fortier LA.

Am J Sports Med. 2014 Jan;42(1):35-41. doi: 10.1177/0363546513507766. Epub 2013 Nov 5.


Cytokine and Growth Factor Concentrations in Canine Autologous Conditioned Serum.

Sawyere DM, Lanz OI, Dahlgren LA, Barry SL, Nichols AC, Werre SR.

Vet Surg. 2016 Jul;45(5):582-6. doi: 10.1111/vsu.12506.


An explorative study comparing levels of soluble mediators in control and osteoarthritic synovial fluid.

Beekhuizen M, Gierman LM, van Spil WE, Van Osch GJ, Huizinga TW, Saris DB, Creemers LB, Zuurmond AM.

Osteoarthritis Cartilage. 2013 Jul;21(7):918-22. doi: 10.1016/j.joca.2013.04.002. Epub 2013 Apr 15.


Safety and Treatment Effectiveness of a Single Autologous Protein Solution Injection in Patients with Knee Osteoarthritis.

van Drumpt RA, van der Weegen W, King W, Toler K, Macenski MM.

Biores Open Access. 2016 Aug 1;5(1):261-8. doi: 10.1089/biores.2016.0014. eCollection 2016.


Growth factor and catabolic cytokine concentrations are influenced by the cellular composition of platelet-rich plasma.

Sundman EA, Cole BJ, Fortier LA.

Am J Sports Med. 2011 Oct;39(10):2135-40. doi: 10.1177/0363546511417792. Epub 2011 Aug 16.


A method to induce Interleukin-1 Receptor Antagonist Protein from autologous whole blood.

Barreto A, Braun TR.

Cytokine. 2016 May;81:137-41. doi: 10.1016/j.cyto.2016.03.008. Epub 2016 Mar 16.


Associations between proinflammatory cytokines in the synovial fluid and radiographic grading and pain-related scores in 47 consecutive patients with osteoarthritis of the knee.

Orita S, Koshi T, Mitsuka T, Miyagi M, Inoue G, Arai G, Ishikawa T, Hanaoka E, Yamashita K, Yamashita M, Eguchi Y, Toyone T, Takahashi K, Ohtori S.

BMC Musculoskelet Disord. 2011 Jun 30;12:144. doi: 10.1186/1471-2474-12-144.


Suppression of experimental osteoarthritis by adenovirus-mediated double gene transfer.

Wang HJ, Yu CL, Kishi H, Motoki K, Mao ZB, Muraguchi A.

Chin Med J (Engl). 2006 Aug 20;119(16):1365-73.


An Autologous Anti-Inflammatory Protein Solution Yielded a Favorable Safety Profile and Significant Pain Relief in an Open-Label Pilot Study of Patients with Osteoarthritis.

Hix J, Klaassen M, Foreman R, Cullen E, Toler K, King W, Woodell-May J.

Biores Open Access. 2017 Dec 1;6(1):151-158. doi: 10.1089/biores.2017.0027. eCollection 2017.


Effect of Chondroitin Sulphate on Pro-Inflammatory Mediators and Disease Activity in Patients with Inflammatory Bowel Disease.

Linares PM, Chaparro M, Algaba A, Román M, Moreno Arza I, Abad Santos F, Ochoa D, Guerra I, Bermejo F, Gisbert JP.

Digestion. 2015;92(4):203-10. doi: 10.1159/000439522. Epub 2015 Sep 19.


Effects over time of two platelet gel supernatants on growth factor, cytokine and hyaluronan concentrations in normal synovial membrane explants challenged with lipopolysaccharide.

Ríos DL, López C, Álvarez ME, Samudio IJ, Carmona JU.

BMC Musculoskelet Disord. 2015 Jun 20;16:153. doi: 10.1186/s12891-015-0605-3.


Differential expression of pro-inflammatory cytokines IL-15Ralpha, IL-15, IL-6 and TNFalpha in synovial fluid from rheumatoid arthritis patients.

Santos Savio A, Machado Diaz AC, Chico Capote A, Miranda Navarro J, Rodríguez Alvarez Y, Bringas Pérez R, Estévez del Toro M, Guillen Nieto GE.

BMC Musculoskelet Disord. 2015 Mar 12;16:51. doi: 10.1186/s12891-015-0516-3.


Synovial membrane inflammation and cytokine production in patients with early osteoarthritis.

Smith MD, Triantafillou S, Parker A, Youssef PP, Coleman M.

J Rheumatol. 1997 Feb;24(2):365-71.


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