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Items: 1 to 20 of 94

1.

Anti-inflammatory effects of 5-HT3 receptor antagonists in interleukin-1beta stimulated primary human chondrocytes.

Stratz C, Anakwue J, Bhatia H, Pitz S, Fiebich BL.

Int Immunopharmacol. 2014 Sep;22(1):160-6. doi: 10.1016/j.intimp.2014.06.003. Epub 2014 Jun 27.

PMID:
24975660
2.

Expression and regulation of microsomal prostaglandin E synthase-1 in human osteoarthritic cartilage and chondrocytes.

Li X, Afif H, Cheng S, Martel-Pelletier J, Pelletier JP, Ranger P, Fahmi H.

J Rheumatol. 2005 May;32(5):887-95.

PMID:
15868626
3.

Serotonin mediates PGE2 overexpression through 5-HT2A and 5-HT3 receptor subtypes in serum-free tissue culture of macrophage-like synovial cells.

Seidel MF, Fiebich BL, Ulrich-Merzenich G, Candelario-Jalil E, Koch FW, Vetter H.

Rheumatol Int. 2008 Aug;28(10):1017-22. doi: 10.1007/s00296-008-0564-1. Epub 2008 Mar 27.

PMID:
18368410
4.

Anti-inflammatory activity of monogalactosyldiacylglycerol in human articular cartilage in vitro: activation of an anti-inflammatory cyclooxygenase-2 (COX-2) pathway.

Ulivi V, Lenti M, Gentili C, Marcolongo G, Cancedda R, Descalzi Cancedda F.

Arthritis Res Ther. 2011 Jun 17;13(3):R92. doi: 10.1186/ar3367.

5.

Membrane-associated prostaglandin E synthase-1 is upregulated by proinflammatory cytokines in chondrocytes from patients with osteoarthritis.

Kojima F, Naraba H, Miyamoto S, Beppu M, Aoki H, Kawai S.

Arthritis Res Ther. 2004;6(4):R355-65. Epub 2004 Jun 8.

6.

Evaluation of coexpression of microsomal prostaglandin E synthase-1 and cyclooxygenase-2 in interleukin-1-stimulated equine articular chondrocytes.

Farley J, Sirois J, MacFarlane PH, Kombé A, Laverty S.

Am J Vet Res. 2005 Nov;66(11):1985-91.

PMID:
16334960
8.

Haem oxygenase-1 counteracts the effects of interleukin-1β on inflammatory and senescence markers in cartilage-subchondral bone explants from osteoarthritic patients.

Clérigues V, Guillén MI, Gomar F, Alcaraz MJ.

Clin Sci (Lond). 2012 Mar;122(5):239-50. doi: 10.1042/CS20100519.

PMID:
21954917
9.

Coexpression of microsomal prostaglandin E synthase with cyclooxygenase-2 in human rheumatoid synovial cells.

Kojima F, Naraba H, Sasaki Y, Okamoto R, Koshino T, Kawai S.

J Rheumatol. 2002 Sep;29(9):1836-42.

PMID:
12233875
11.

Phase 2 enzyme inducer sulphoraphane blocks prostaglandin and nitric oxide synthesis in human articular chondrocytes and inhibits cartilage matrix degradation.

Kim HA, Yeo Y, Jung HA, Jung YO, Park SJ, Kim SJ.

Rheumatology (Oxford). 2012 Jun;51(6):1006-16. doi: 10.1093/rheumatology/ker525. Epub 2012 Feb 12.

PMID:
22332123
12.

Regulation of prostaglandin E(2) synthesis in cells derived from chondrocytes of patients with osteoarthritis.

Shimpo H, Sakai T, Kondo S, Mishima S, Yoda M, Hiraiwa H, Ishiguro N.

J Orthop Sci. 2009 Sep;14(5):611-7. doi: 10.1007/s00776-009-1370-7. Epub 2009 Oct 3.

PMID:
19802674
13.

The anti-inflammatory effects of the 5-HT₃ receptor antagonist tropisetron are mediated by the inhibition of p38 MAPK activation in primary human monocytes.

Stratz C, Bhatia HS, Akundi RS, Nührenberg T, Trenk D, Muñoz E, Fiebich BL.

Int Immunopharmacol. 2012 Aug;13(4):398-402. doi: 10.1016/j.intimp.2012.05.013. Epub 2012 Jun 1.

PMID:
22664143
14.
15.

IL-1β/HMGB1 complexes promote The PGE2 biosynthesis pathway in synovial fibroblasts.

Leclerc P, Wähämaa H, Idborg H, Jakobsson PJ, Harris HE, Korotkova M.

Scand J Immunol. 2013 May;77(5):350-60. doi: 10.1111/sji.12041.

16.

Aurothiomalate inhibits the expression of mPGES-1 in primary human chondrocytes.

Tuure L, Hämäläinen M, Moilanen T, Moilanen E.

Scand J Rheumatol. 2015;44(1):74-9. doi: 10.3109/03009742.2014.927917. Epub 2014 Oct 14.

PMID:
25314295
17.

Inhibition of matrix metalloproteinase-3 and -13 synthesis induced by IL-1beta in chondrocytes from mice lacking microsomal prostaglandin E synthase-1.

Gosset M, Pigenet A, Salvat C, Berenbaum F, Jacques C.

J Immunol. 2010 Nov 15;185(10):6244-52. doi: 10.4049/jimmunol.0903315. Epub 2010 Oct 13.

18.

In vitro effects of aceclofenac and its metabolites on the production by chondrocytes of inflammatory mediators.

Henrotin Y, de Leval X, Mathy-Hartet M, Mouithys-Mickalad A, Deby-Dupont G, Dogné JM, Delarge J, Reginster JY.

Inflamm Res. 2001 Aug;50(8):391-9.

PMID:
11556519
19.

The CO-releasing molecule CORM-2 is a novel regulator of the inflammatory process in osteoarthritic chondrocytes.

Guillén MI, Megías J, Clérigues V, Gomar F, Alcaraz MJ.

Rheumatology (Oxford). 2008 Sep;47(9):1323-8. doi: 10.1093/rheumatology/ken264. Epub 2008 Jul 11.

PMID:
18621749
20.

Heme oxygenase-1 induction modulates microsomal prostaglandin E synthase-1 expression and prostaglandin E(2) production in osteoarthritic chondrocytes.

Megías J, Guillén MI, Clérigues V, Rojo AI, Cuadrado A, Castejón MA, Gomar F, Alcaraz MJ.

Biochem Pharmacol. 2009 Jun 15;77(12):1806-13. doi: 10.1016/j.bcp.2009.03.009. Epub 2009 Mar 21.

PMID:
19428335

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