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Items: 1 to 20 of 114

1.

20(S)-Ginsenoside Rg3 is a novel inhibitor of autophagy and sensitizes hepatocellular carcinoma to doxorubicin.

Kim DG, Jung KH, Lee DG, Yoon JH, Choi KS, Kwon SW, Shen HM, Morgan MJ, Hong SS, Kim YS.

Oncotarget. 2014 Jun 30;5(12):4438-51.

2.

Sensitization of TRAIL-induced cell death by 20(S)-ginsenoside Rg3 via CHOP-mediated DR5 upregulation in human hepatocellular carcinoma cells.

Lee JY, Jung KH, Morgan MJ, Kang YR, Lee HS, Koo GB, Hong SS, Kwon SW, Kim YS.

Mol Cancer Ther. 2013 Mar;12(3):274-85. doi: 10.1158/1535-7163.MCT-12-0054. Epub 2012 Oct 10.

3.

Ginsenoside Rg3 inhibit hepatocellular carcinoma growth via intrinsic apoptotic pathway.

Jiang JW, Chen XM, Chen XH, Zheng SS.

World J Gastroenterol. 2011 Aug 21;17(31):3605-13. doi: 10.3748/wjg.v17.i31.3605.

4.

A hepatocellular carcinoma-specific adenovirus variant, CV890, eliminates distant human liver tumors in combination with doxorubicin.

Li Y, Yu DC, Chen Y, Amin P, Zhang H, Nguyen N, Henderson DR.

Cancer Res. 2001 Sep 1;61(17):6428-36.

5.

The AKT inhibitor MK-2206 is cytotoxic in hepatocarcinoma cells displaying hyperphosphorylated AKT-1 and synergizes with conventional chemotherapy.

Simioni C, Martelli AM, Cani A, Cetin-Atalay R, McCubrey JA, Capitani S, Neri LM.

Oncotarget. 2013 Sep;4(9):1496-506.

6.

Antitumor effects of ginsenoside Rg3 on human hepatocellular carcinoma cells.

Zhang C, Liu L, Yu Y, Chen B, Tang C, Li X.

Mol Med Rep. 2012 May;5(5):1295-8. doi: 10.3892/mmr.2012.808. Epub 2012 Feb 23.

PMID:
22366885
7.

MicroRNA-101 inhibits human hepatocellular carcinoma progression through EZH2 downregulation and increased cytostatic drug sensitivity.

Xu L, Beckebaum S, Iacob S, Wu G, Kaiser GM, Radtke A, Liu C, Kabar I, Schmidt HH, Zhang X, Lu M, Cicinnati VR.

J Hepatol. 2014 Mar;60(3):590-8. doi: 10.1016/j.jhep.2013.10.028. Epub 2013 Nov 6.

PMID:
24211739
8.

Inhibition of doxorubicin-induced autophagy in hepatocellular carcinoma Hep3B cells by sorafenib--the role of extracellular signal-regulated kinase counteraction.

Manov I, Pollak Y, Broneshter R, Iancu TC.

FEBS J. 2011 Sep;278(18):3494-507. doi: 10.1111/j.1742-4658.2011.08271.x.

9.

Stereospecificity of ginsenoside Rg3 in the promotion of cellular immunity in hepatoma H22-bearing mice.

Wu R, Ru Q, Chen L, Ma B, Li C.

J Food Sci. 2014 Jul;79(7):H1430-5. doi: 10.1111/1750-3841.12518.

PMID:
25041540
10.

Effects of R type and S type ginsenoside Rg3 on DNA methylation in human hepatocarcinoma cells.

Teng S, Wang Y, Li P, Liu J, Wei A, Wang H, Meng X, Pan D, Zhang X.

Mol Med Rep. 2017 Apr;15(4):2029-2038. doi: 10.3892/mmr.2017.6255. Epub 2017 Feb 28.

11.

Nutlin-3 cooperates with doxorubicin to induce apoptosis of human hepatocellular carcinoma cells through p53 or p73 signaling pathways.

Zheng T, Wang J, Song X, Meng X, Pan S, Jiang H, Liu L.

J Cancer Res Clin Oncol. 2010 Oct;136(10):1597-604. doi: 10.1007/s00432-010-0817-8. Epub 2010 Feb 20.

PMID:
20174822
12.

The effect of doxorubicin on MEK-ERK signaling predicts its efficacy in HCC.

Choi J, Yip-Schneider M, Albertin F, Wiesenauer C, Wang Y, Schmidt CM.

J Surg Res. 2008 Dec;150(2):219-26. doi: 10.1016/j.jss.2008.01.029. Epub 2008 Mar 3.

PMID:
18468633
13.

Inhibition of NF-kappaB by ginsenoside Rg3 enhances the susceptibility of colon cancer cells to docetaxel.

Kim SM, Lee SY, Yuk DY, Moon DC, Choi SS, Kim Y, Han SB, Oh KW, Hong JT.

Arch Pharm Res. 2009 May;32(5):755-65. doi: 10.1007/s12272-009-1515-4. Epub 2009 May 27.

PMID:
19471891
14.

Inhibitory effect of ginsenoside Rg3 combined with gemcitabine on angiogenesis and growth of lung cancer in mice.

Liu TG, Huang Y, Cui DD, Huang XB, Mao SH, Ji LL, Song HB, Yi C.

BMC Cancer. 2009 Jul 23;9:250. doi: 10.1186/1471-2407-9-250.

15.

Autophagy inhibition contributes to the synergistic interaction between EGCG and doxorubicin to kill the hepatoma Hep3B cells.

Chen L, Ye HL, Zhang G, Yao WM, Chen XZ, Zhang FC, Liang G.

PLoS One. 2014 Jan 21;9(1):e85771. doi: 10.1371/journal.pone.0085771. eCollection 2014.

16.

Ginsenoside Rg3 sensitizes human non-small cell lung cancer cells to γ-radiation by targeting the nuclear factor-κB pathway.

Wang L, Li X, Song YM, Wang B, Zhang FR, Yang R, Wang HQ, Zhang GJ.

Mol Med Rep. 2015 Jul;12(1):609-14. doi: 10.3892/mmr.2015.3397. Epub 2015 Feb 27.

PMID:
25738799
17.

Ginsenoside 20(S)-Rg3 induced autophagy to inhibit migration and invasion of ovarian cancer.

Zheng X, Chen W, Hou H, Li J, Li H, Sun X, Zhao L, Li X.

Biomed Pharmacother. 2017 Jan;85:620-626. doi: 10.1016/j.biopha.2016.11.072. Epub 2016 Nov 26.

PMID:
27899249
18.
19.

Modulation of Doxorubicin mediated growth inhibition of hepatocellular carcinoma cells by platelet lysates.

Refolo MG, D'Alessandro R, Lippolis C, Messa C, Carella N, Cavallini A, Carr BI.

Anticancer Agents Med Chem. 2014;14(8):1154-60.

PMID:
24934165
20.

Targeting autophagy enhances sorafenib lethality for hepatocellular carcinoma via ER stress-related apoptosis.

Shi YH, Ding ZB, Zhou J, Hui B, Shi GM, Ke AW, Wang XY, Dai Z, Peng YF, Gu CY, Qiu SJ, Fan J.

Autophagy. 2011 Oct;7(10):1159-72. doi: 10.4161/auto.7.10.16818. Epub 2011 Oct 1.

PMID:
21691147

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