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Items: 1 to 20 of 88

1.

PACAP27 prevents Parkinson-like neuronal loss and motor deficits but not microglia activation induced by prostaglandin J2.

Shivers KY, Nikolopoulou A, Machlovi SI, Vallabhajosula S, Figueiredo-Pereira ME.

Biochim Biophys Acta. 2014 Sep;1842(9):1707-19. doi: 10.1016/j.bbadis.2014.06.020. Epub 2014 Jun 23.

2.

Prostaglandin D2/J2 signaling pathway in a rat model of neuroinflammation displaying progressive parkinsonian-like pathology: potential novel therapeutic targets.

Corwin C, Nikolopoulou A, Pan AL, Nunez-Santos M, Vallabhajosula S, Serrano P, Babich J, Figueiredo-Pereira ME.

J Neuroinflammation. 2018 Sep 20;15(1):272. doi: 10.1186/s12974-018-1305-3.

3.

Subchronic infusion of the product of inflammation prostaglandin J2 models sporadic Parkinson's disease in mice.

Pierre SR, Lemmens MA, Figueiredo-Pereira ME.

J Neuroinflammation. 2009 Jul 25;6:18. doi: 10.1186/1742-2094-6-18.

4.

Prostaglandin J2: a potential target for halting inflammation-induced neurodegeneration.

Figueiredo-Pereira ME, Corwin C, Babich J.

Ann N Y Acad Sci. 2016 Jan;1363:125-37. doi: 10.1111/nyas.12987. Epub 2016 Jan 8. Review.

5.

Activation of microglia induces symptoms of Parkinson's disease in wild-type, but not in IL-1 knockout mice.

Tanaka S, Ishii A, Ohtaki H, Shioda S, Yoshida T, Numazawa S.

J Neuroinflammation. 2013 Dec 1;10:143. doi: 10.1186/1742-2094-10-143.

6.

N-acetylcysteine prevents loss of dopaminergic neurons in the EAAC1-/- mouse.

Berman AE, Chan WY, Brennan AM, Reyes RC, Adler BL, Suh SW, Kauppinen TM, Edling Y, Swanson RA.

Ann Neurol. 2011 Mar;69(3):509-20. doi: 10.1002/ana.22162. Epub 2010 Nov 23.

7.

Chronic expression of low levels of tumor necrosis factor-alpha in the substantia nigra elicits progressive neurodegeneration, delayed motor symptoms and microglia/macrophage activation.

De Lella Ezcurra AL, Chertoff M, Ferrari C, Graciarena M, Pitossi F.

Neurobiol Dis. 2010 Mar;37(3):630-40. doi: 10.1016/j.nbd.2009.11.018. Epub 2009 Dec 5.

PMID:
19969084
8.

Neuroinflammation in the living brain of Parkinson's disease.

Ouchi Y, Yagi S, Yokokura M, Sakamoto M.

Parkinsonism Relat Disord. 2009 Dec;15 Suppl 3:S200-4. doi: 10.1016/S1353-8020(09)70814-4. Review.

PMID:
20082990
9.

The protective effects of 15-deoxy-delta-(12,14)-prostaglandin J2 in spinal cord injury.

Kerr BJ, Girolami EI, Ghasemlou N, Jeong SY, David S.

Glia. 2008 Mar;56(4):436-48. doi: 10.1002/glia.20630.

PMID:
18205174
10.

PACAP deficiency sensitizes nigrostriatal dopaminergic neurons to paraquat-induced damage and modulates central and peripheral inflammatory activation in mice.

Watson MB, Nobuta H, Abad C, Lee SK, Bala N, Zhu C, Richter F, Chesselet MF, Waschek JA.

Neuroscience. 2013 Jun 14;240:277-86. doi: 10.1016/j.neuroscience.2013.03.002. Epub 2013 Mar 14.

11.

Neurotoxic prostaglandin J2 enhances cyclooxygenase-2 expression in neuronal cells through the p38MAPK pathway: a death wish?

Li Z, Jansen M, Ogburn K, Salvatierra L, Hunter L, Mathew S, Figueiredo-Pereira ME.

J Neurosci Res. 2004 Dec 15;78(6):824-36.

PMID:
15523637
12.

Pituitary adenylate cyclase activating polypeptide protects dopaminergic neurons and improves behavioral deficits in a rat model of Parkinson's disease.

Reglodi D, Lubics A, Tamás A, Szalontay L, Lengvári I.

Behav Brain Res. 2004 May 5;151(1-2):303-12.

PMID:
15084446
13.

Somatostatin prevents lipopolysaccharide-induced neurodegeneration in the rat substantia nigra by inhibiting the activation of microglia.

Bai L, Zhang X, Li X, Liu N, Lou F, Ma H, Luo X, Ren Y.

Mol Med Rep. 2015 Jul;12(1):1002-8. doi: 10.3892/mmr.2015.3494. Epub 2015 Mar 13.

14.

Fyn Kinase Regulates Microglial Neuroinflammatory Responses in Cell Culture and Animal Models of Parkinson's Disease.

Panicker N, Saminathan H, Jin H, Neal M, Harischandra DS, Gordon R, Kanthasamy K, Lawana V, Sarkar S, Luo J, Anantharam V, Kanthasamy AG, Kanthasamy A.

J Neurosci. 2015 Jul 8;35(27):10058-77. doi: 10.1523/JNEUROSCI.0302-15.2015.

15.

Neuroinflammation in Alzheimer's disease and Parkinson's disease: are microglia pathogenic in either disorder?

Rogers J, Mastroeni D, Leonard B, Joyce J, Grover A.

Int Rev Neurobiol. 2007;82:235-46. Review.

PMID:
17678964
17.

Proteasome-caspase-cathepsin sequence leading to tau pathology induced by prostaglandin J2 in neuronal cells.

Arnaud LT, Myeku N, Figueiredo-Pereira ME.

J Neurochem. 2009 Jul;110(1):328-42. doi: 10.1111/j.1471-4159.2009.06142.x. Epub 2009 May 3.

18.
19.

A novel compound VSC2 has anti-inflammatory and antioxidant properties in microglia and in Parkinson's disease animal model.

Lee JA, Kim JH, Woo SY, Son HJ, Han SH, Jang BK, Choi JW, Kim DJ, Park KD, Hwang O.

Br J Pharmacol. 2015 Feb;172(4):1087-100. doi: 10.1111/bph.12973. Epub 2014 Dec 15.

20.

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