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Items: 1 to 20 of 101


Site-selective solid-phase synthesis of a CCR5 sulfopeptide library to interrogate HIV binding and entry.

Liu X, Malins LR, Roche M, Sterjovski J, Duncan R, Garcia ML, Barnes NC, Anderson DA, Stone MJ, Gorry PR, Payne RJ.

ACS Chem Biol. 2014 Sep 19;9(9):2074-81. doi: 10.1021/cb500337r. Epub 2014 Jul 24.


Homogeneous sulfopeptides and sulfoproteins: synthetic approaches and applications to characterize the effects of tyrosine sulfation on biochemical function.

Stone MJ, Payne RJ.

Acc Chem Res. 2015 Aug 18;48(8):2251-61. doi: 10.1021/acs.accounts.5b00255. Epub 2015 Jul 21.


Tyrosine sulfation of CCR5 N-terminal peptide by tyrosylprotein sulfotransferases 1 and 2 follows a discrete pattern and temporal sequence.

Seibert C, Cadene M, Sanfiz A, Chait BT, Sakmar TP.

Proc Natl Acad Sci U S A. 2002 Aug 20;99(17):11031-6. Epub 2002 Aug 8.


Tyrosine-sulfate isosteres of CCR5 N-terminus as tools for studying HIV-1 entry.

Lam SN, Acharya P, Wyatt R, Kwong PD, Bewley CA.

Bioorg Med Chem. 2008 Dec 1;16(23):10113-20. doi: 10.1016/j.bmc.2008.10.005. Epub 2008 Oct 5.


A highly conserved arginine in gp120 governs HIV-1 binding to both syndecans and CCR5 via sulfated motifs.

de Parseval A, Bobardt MD, Chatterji A, Chatterji U, Elder JH, David G, Zolla-Pazner S, Farzan M, Lee TH, Gallay PA.

J Biol Chem. 2005 Nov 25;280(47):39493-504. Epub 2005 Sep 12.


Tyrosine-sulfated V2 peptides inhibit HIV-1 infection via coreceptor mimicry.

Cimbro R, Peterson FC, Liu Q, Guzzo C, Zhang P, Miao H, Van Ryk D, Ambroggio X, Hurt DE, De Gioia L, Volkman BF, Dolan MA, Lusso P.

EBioMedicine. 2016 Aug;10:45-54. doi: 10.1016/j.ebiom.2016.06.037. Epub 2016 Jun 26.


Binding thermodynamics of the N-terminal peptide of the CCR5 coreceptor to HIV-1 envelope glycoprotein gp120.

Brower ET, Schön A, Klein JC, Freire E.

Biochemistry. 2009 Feb 3;48(4):779-85. doi: 10.1021/bi8021476.


Specific interaction of CCR5 amino-terminal domain peptides containing sulfotyrosines with HIV-1 envelope glycoprotein gp120.

Cormier EG, Persuh M, Thompson DA, Lin SW, Sakmar TP, Olson WC, Dragic T.

Proc Natl Acad Sci U S A. 2000 May 23;97(11):5762-7.


The conformation and orientation of a 27-residue CCR5 peptide in a ternary complex with HIV-1 gp120 and a CD4-mimic peptide.

Schnur E, Noah E, Ayzenshtat I, Sargsyan H, Inui T, Ding FX, Arshava B, Sagi Y, Kessler N, Levy R, Scherf T, Naider F, Anglister J.

J Mol Biol. 2011 Jul 29;410(5):778-97. doi: 10.1016/j.jmb.2011.04.023. Erratum in: J Mol Biol. 2012 Apr 20;418(1-2):127.


Structures of the CCR5 N terminus and of a tyrosine-sulfated antibody with HIV-1 gp120 and CD4.

Huang CC, Lam SN, Acharya P, Tang M, Xiang SH, Hussan SS, Stanfield RL, Robinson J, Sodroski J, Wilson IA, Wyatt R, Bewley CA, Kwong PD.

Science. 2007 Sep 28;317(5846):1930-4.


Functional mimicry of a human immunodeficiency virus type 1 coreceptor by a neutralizing monoclonal antibody.

Xiang SH, Farzan M, Si Z, Madani N, Wang L, Rosenberg E, Robinson J, Sodroski J.

J Virol. 2005 May;79(10):6068-77.


Effect of amino acid substitution of the V3 and bridging sheet residues in human immunodeficiency virus type 1 subtype C gp120 on CCR5 utilization.

Suphaphiphat P, Thitithanyanont A, Paca-Uccaralertkun S, Essex M, Lee TH.

J Virol. 2003 Mar;77(6):3832-7.


Tyrosine sulfation of human antibodies contributes to recognition of the CCR5 binding region of HIV-1 gp120.

Choe H, Li W, Wright PL, Vasilieva N, Venturi M, Huang CC, Grundner C, Dorfman T, Zwick MB, Wang L, Rosenberg ES, Kwong PD, Burton DR, Robinson JE, Sodroski JG, Farzan M.

Cell. 2003 Jul 25;114(2):161-70.


A critical site in the core of the CCR5 chemokine receptor required for binding and infectivity of human immunodeficiency virus type 1.

Siciliano SJ, Kuhmann SE, Weng Y, Madani N, Springer MS, Lineberger JE, Danzeisen R, Miller MD, Kavanaugh MP, DeMartino JA, Kabat D.

J Biol Chem. 1999 Jan 22;274(4):1905-13.


Reversible and efficient activation of HIV-1 cell entry by a tyrosine-sulfated peptide dissects endocytic entry and inhibitor mechanisms.

Platt EJ, Gomes MM, Kabat D.

J Virol. 2014 Apr;88(8):4304-18. doi: 10.1128/JVI.03447-13. Epub 2014 Jan 29.


Tyrosine sulfation of the amino terminus of CCR5 facilitates HIV-1 entry.

Farzan M, Mirzabekov T, Kolchinsky P, Wyatt R, Cayabyab M, Gerard NP, Gerard C, Sodroski J, Choe H.

Cell. 1999 Mar 5;96(5):667-76.

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