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Items: 1 to 20 of 85

1.

Nuclear MEK1 sequesters PPARγ and bisects MEK1/ERK signaling: a non-canonical pathway of retinoic acid inhibition of adipocyte differentiation.

Dave S, Nanduri R, Dkhar HK, Bhagyaraj E, Rao A, Gupta P.

PLoS One. 2014 Jun 24;9(6):e100862. doi: 10.1371/journal.pone.0100862. eCollection 2014.

3.

Aristolochia manshuriensis Kom inhibits adipocyte differentiation by regulation of ERK1/2 and Akt pathway.

Kwak DH, Lee JH, Kim T, Ahn HS, Cho WK, Ha H, Hwang YH, Ma JY.

PLoS One. 2012;7(11):e49530. doi: 10.1371/journal.pone.0049530. Epub 2012 Nov 14.

4.

MicroRNA-375 promotes 3T3-L1 adipocyte differentiation through modulation of extracellular signal-regulated kinase signalling.

Ling HY, Wen GB, Feng SD, Tuo QH, Ou HS, Yao CH, Zhu BY, Gao ZP, Zhang L, Liao DF.

Clin Exp Pharmacol Physiol. 2011 Apr;38(4):239-46. doi: 10.1111/j.1440-1681.2011.05493.x.

5.

Coordinate functional regulation between microsomal prostaglandin E synthase-1 (mPGES-1) and peroxisome proliferator-activated receptor γ (PPARγ) in the conversion of white-to-brown adipocytes.

García-Alonso V, López-Vicario C, Titos E, Morán-Salvador E, González-Périz A, Rius B, Párrizas M, Werz O, Arroyo V, Clària J.

J Biol Chem. 2013 Sep 27;288(39):28230-42. doi: 10.1074/jbc.M113.468603. Epub 2013 Aug 13.

6.

Pigment epithelium-derived factor suppresses adipogenesis via inhibition of the MAPK/ERK pathway in 3T3-L1 preadipocytes.

Wang M, Wang JJ, Li J, Park K, Qian X, Ma JX, Zhang SX.

Am J Physiol Endocrinol Metab. 2009 Dec;297(6):E1378-87. doi: 10.1152/ajpendo.00252.2009. Epub 2009 Oct 6.

7.

Retinoic acid inhibits adipogenesis via activation of Wnt signaling pathway in 3T3-L1 preadipocytes.

Kim DM, Choi HR, Park A, Shin SM, Bae KH, Lee SC, Kim IC, Kim WK.

Biochem Biophys Res Commun. 2013 May 10;434(3):455-9. doi: 10.1016/j.bbrc.2013.03.095. Epub 2013 Apr 10.

PMID:
23583383
8.

Coprinus comatus cap inhibits adipocyte differentiation via regulation of PPARγ and Akt signaling pathway.

Park HJ, Yun J, Jang SH, Kang SN, Jeon BS, Ko YG, Kim HD, Won CK, Kim GS, Cho JH.

PLoS One. 2014 Sep 2;9(9):e105809. doi: 10.1371/journal.pone.0105809. eCollection 2014.

9.

Zanthoxylum schinifolium leaf ethanol extract inhibits adipocyte differentiation through inactivation of the extracellular signal regulated kinase and phosphoinositide 3-kinase/Akt signaling pathways in 3T3-L1 pre-adipocytes.

Choi EO, Park C, Shin SS, Cho EJ, Kim BW, Hwang JA, Hwang HJ, Choi YH.

Mol Med Rep. 2015 Jul;12(1):1314-20. doi: 10.3892/mmr.2015.3463. Epub 2015 Mar 10.

PMID:
25760758
10.

Mammalian ste20-like kinase and SAV1 promote 3T3-L1 adipocyte differentiation by activation of PPARγ.

Park BH, Kim DS, Won GW, Jeon HJ, Oh BC, Lee Y, Kim EG, Lee YH.

PLoS One. 2012;7(1):e30983. doi: 10.1371/journal.pone.0030983. Epub 2012 Jan 26. Erratum in: PLoS One. 2015;10(3):e0119098.

11.

Brd2 inhibits adipogenesis via the ERK1/2 signaling pathway in 3T3-L1 adipocytes.

Zang K, Wang J, Dong M, Sun R, Wang Y, Huang Y, Liu X, Li Y, Wang F, Yu M.

PLoS One. 2013 Oct 23;8(10):e78536. doi: 10.1371/journal.pone.0078536. eCollection 2013.

12.

Fucoidan, a sulfated polysaccharide, inhibits adipogenesis through the mitogen-activated protein kinase pathway in 3T3-L1 preadipocytes.

Kim KJ, Lee OH, Lee BY.

Life Sci. 2010 May 22;86(21-22):791-7. doi: 10.1016/j.lfs.2010.03.010. Epub 2010 Mar 25.

PMID:
20346961
13.

3-phosphoinositide-dependent protein kinase-1 activates the peroxisome proliferator-activated receptor-gamma and promotes adipocyte differentiation.

Yin Y, Yuan H, Wang C, Pattabiraman N, Rao M, Pestell RG, Glazer RI.

Mol Endocrinol. 2006 Feb;20(2):268-78. Epub 2005 Sep 8.

PMID:
16150867
14.

Lipin-1 phosphatidic phosphatase activity modulates phosphatidate levels to promote peroxisome proliferator-activated receptor γ (PPARγ) gene expression during adipogenesis.

Zhang P, Takeuchi K, Csaki LS, Reue K.

J Biol Chem. 2012 Jan 27;287(5):3485-94. doi: 10.1074/jbc.M111.296681. Epub 2011 Dec 6.

15.

Retinoic acid activation of the ERK pathway is required for embryonic stem cell commitment into the adipocyte lineage.

Bost F, Caron L, Marchetti I, Dani C, Le Marchand-Brustel Y, Binétruy B.

Biochem J. 2002 Feb 1;361(Pt 3):621-7.

16.

De-novo identification of PPARgamma/RXR binding sites and direct targets during adipogenesis.

Hamza MS, Pott S, Vega VB, Thomsen JS, Kandhadayar GS, Ng PW, Chiu KP, Pettersson S, Wei CL, Ruan Y, Liu ET.

PLoS One. 2009;4(3):e4907. doi: 10.1371/journal.pone.0004907. Epub 2009 Mar 20.

17.

A widely used retinoic acid receptor antagonist induces peroxisome proliferator-activated receptor-gamma activity.

Schupp M, Curtin JC, Kim RJ, Billin AN, Lazar MA.

Mol Pharmacol. 2007 May;71(5):1251-7. Epub 2007 Feb 8.

18.

RARγ-C-Fos-PPARγ2 signaling rather than ROS generation is critical for all-trans retinoic acid-inhibited adipocyte differentiation.

Wang X, Yang P, Liu J, Wu H, Yu W, Zhang T, Fu H, Liu Y, Hai C.

Biochimie. 2014 Nov;106:121-30. doi: 10.1016/j.biochi.2014.08.009. Epub 2014 Aug 28.

PMID:
25173565
19.

ATF3 represses PPARγ expression and inhibits adipocyte differentiation.

Jang MK, Jung MH.

Biochem Biophys Res Commun. 2014 Nov 7;454(1):58-64. doi: 10.1016/j.bbrc.2014.10.028. Epub 2014 Oct 14.

PMID:
25445599
20.

The chalcones cardamonin and flavokawain B inhibit the differentiation of preadipocytes to adipocytes by activating ERK.

Zhang T, Yamamoto N, Yamashita Y, Ashida H.

Arch Biochem Biophys. 2014 Jul 15;554:44-54. doi: 10.1016/j.abb.2014.05.008. Epub 2014 May 17.

PMID:
24845100

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