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Proteome-wide analysis of HIV-specific naive and memory CD4(+) T cells in unexposed blood donors.

Campion SL, Brodie TM, Fischer W, Korber BT, Rossetti A, Goonetilleke N, McMichael AJ, Sallusto F.

J Exp Med. 2014 Jun 30;211(7):1273-80. doi: 10.1084/jem.20130555.


Hierarchy of CD4 T cell epitopes of the ANRS Lipo5 synthetic vaccine relies on the frequencies of pre-existing peptide-specific T cells in healthy donors.

Castelli FA, Szely N, Olivain A, Casartelli N, Grygar C, Schneider A, Besse A, Levy Y, Schwartz O, Maillère B.

J Immunol. 2013 Jun 1;190(11):5757-63. doi: 10.4049/jimmunol.1300145.


Specificity of T cells in synovial fluid: high frequencies of CD8(+) T cells that are specific for certain viral epitopes.

Tan LC, Mowat AG, Fazou C, Rostron T, Roskell H, Dunbar PR, Tournay C, Romagné F, Peyrat MA, Houssaint E, Bonneville M, Rickinson AB, McMichael AJ, Callan MF.

Arthritis Res. 2000;2(2):154-64.


A human immune data-informed vaccine concept elicits strong and broad T-cell specificities associated with HIV-1 control in mice and macaques.

Mothe B, Hu X, Llano A, Rosati M, Olvera A, Kulkarni V, Valentin A, Alicea C, Pilkington GR, Sardesai NY, Rocafort M, Crespo M, Carrillo J, Marco A, Mullins JI, Dorrell L, Hanke T, Clotet B, Pavlakis GN, Felber BK, Brander C.

J Transl Med. 2015 Feb 15;13:60. doi: 10.1186/s12967-015-0392-5.


Broad and cross-clade CD4+ T-cell responses elicited by a DNA vaccine encoding highly conserved and promiscuous HIV-1 M-group consensus peptides.

Almeida RR, Rosa DS, Ribeiro SP, Santana VC, Kallás EG, Sidney J, Sette A, Kalil J, Cunha-Neto E.

PLoS One. 2012;7(9):e45267. doi: 10.1371/journal.pone.0045267.


Identification and antigenicity of broadly cross-reactive and conserved human immunodeficiency virus type 1-derived helper T-lymphocyte epitopes.

Wilson CC, Palmer B, Southwood S, Sidney J, Higashimoto Y, Appella E, Chesnut R, Sette A, Livingston BD.

J Virol. 2001 May;75(9):4195-207.


HIV-1 variation diminishes CD4 T lymphocyte recognition.

Harcourt GC, Garrard S, Davenport MP, Edwards A, Phillips RE.

J Exp Med. 1998 Nov 16;188(10):1785-93.


The HIV-1 HLA-A2-SLYNTVATL is a help-independent CTL epitope.

Kan-Mitchell J, Bisikirska B, Wong-Staal F, Schaubert KL, Bajcz M, Bereta M.

J Immunol. 2004 May 1;172(9):5249-61.


Functional characterization of ocular-derived human alphaherpesvirus cross-reactive CD4 T cells.

Ouwendijk WJ, Geluk A, Smits SL, Getu S, Osterhaus AD, Verjans GM.

J Immunol. 2014 Apr 15;192(8):3730-9. doi: 10.4049/jimmunol.1302307.


Frequency of epitope-specific naive CD4(+) T cells correlates with immunodominance in the human memory repertoire.

Kwok WW, Tan V, Gillette L, Littell CT, Soltis MA, LaFond RB, Yang J, James EA, DeLong JH.

J Immunol. 2012 Mar 15;188(6):2537-44. doi: 10.4049/jimmunol.1102190.


Therapeutic vaccination using cationic liposome-adjuvanted HIV type 1 peptides representing HLA-supertype-restricted subdominant T cell epitopes: safety, immunogenicity, and feasibility in Guinea-Bissau.

Román VR, Jensen KJ, Jensen SS, Leo-Hansen C, Jespersen S, da Silva Té D, Rodrigues CM, Janitzek CM, Vinner L, Katzenstein TL, Andersen P, Kromann I, Andreasen LV, Karlsson I, Fomsgaard A.

AIDS Res Hum Retroviruses. 2013 Nov;29(11):1504-12. doi: 10.1089/AID.2013.0076.


Therapeutic HIV Peptide Vaccine.

Fomsgaard A.

Methods Mol Biol. 2015;1348:351-7. doi: 10.1007/978-1-4939-2999-3_30.


Clinical Control of HIV-1 by Cytotoxic T Cells Specific for Multiple Conserved Epitopes.

Murakoshi H, Akahoshi T, Koyanagi M, Chikata T, Naruto T, Maruyama R, Tamura Y, Ishizuka N, Gatanaga H, Oka S, Takiguchi M.

J Virol. 2015 May;89(10):5330-9. doi: 10.1128/JVI.00020-15.


Direct interrogation of viral peptides presented by the class I HLA of HIV-infected T cells.

Yaciuk JC, Skaley M, Bardet W, Schafer F, Mojsilovic D, Cate S, Stewart CJ, McMurtrey C, Jackson KW, Buchli R, Olvera A, Cedeño S, Plana M, Mothe B, Brander C, West JT, Hildebrand WH.

J Virol. 2014 Nov;88(22):12992-3004. doi: 10.1128/JVI.01914-14.


Preclinical evaluation of HIV-1 therapeutic ex vivo dendritic cell vaccines expressing consensus Gag antigens and conserved Gag epitopes.

Niu L, Termini JM, Kanagavelu SK, Gupta S, Rolland MM, Kulkarni V, Pavlakis GN, Felber BK, Mullins JI, Fischl MA, Stone GW.

Vaccine. 2011 Mar 3;29(11):2110-9. doi: 10.1016/j.vaccine.2010.12.131.


HLA-A02:01-restricted epitopes identified from the herpes simplex virus tegument protein VP11/12 preferentially recall polyfunctional effector memory CD8+ T cells from seropositive asymptomatic individuals and protect humanized HLA-A*02:01 transgenic mice against ocular herpes.

Srivastava R, Khan AA, Spencer D, Vahed H, Lopes PP, Thai NT, Wang C, Pham TT, Huang J, Scarfone VM, Nesburn AB, Wechsler SL, BenMohamed L.

J Immunol. 2015 Mar 1;194(5):2232-48. doi: 10.4049/jimmunol.1402606.

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