Similar articles for PMID: 24956197

Year	Number of Results
2000	1
2003	1
2005	1
2006	6
2007	5
2008	6
2009	3
2010	5
2011	7
2012	3
2013	8
2014	4
2015	10
2016	16
2017	9
2018	10
2019	6
2020	11
2021	9
2022	9
2023	5
2024	0

1

From pan-reactive KV7 channel opener to subtype selective opener/inhibitor by addition of a methyl group.

Blom SM, Rottländer M, Kehler J, Bundgaard C, Schmitt N, Jensen HS. Blom SM, et al. PLoS One. 2014 Jun 23;9(6):e100209. doi: 10.1371/journal.pone.0100209. eCollection 2014. PLoS One. 2014. PMID: 24956197 Free PMC article.

2

Electrophysiological and pharmacological characterization of a novel and potent neuronal Kv7 channel opener SCR2682 for antiepilepsy.

Zhang F, Liu Y, Tang F, Liang B, Chen H, Zhang H, Wang K. Zhang F, et al. FASEB J. 2019 Aug;33(8):9154-9166. doi: 10.1096/fj.201802848RR. Epub 2019 May 7. FASEB J. 2019. PMID: 31063701

3

The KCNQ2/3 selective channel opener ICA-27243 binds to a novel voltage-sensor domain site.

Padilla K, Wickenden AD, Gerlach AC, McCormack K. Padilla K, et al. Neurosci Lett. 2009 Nov 13;465(2):138-42. doi: 10.1016/j.neulet.2009.08.071. Epub 2009 Sep 3. Neurosci Lett. 2009. PMID: 19733209

4

The acrylamide (S)-2 as a positive and negative modulator of Kv7 channels expressed in Xenopus laevis oocytes.

Blom SM, Schmitt N, Jensen HS. Blom SM, et al. PLoS One. 2009 Dec 11;4(12):e8251. doi: 10.1371/journal.pone.0008251. PLoS One. 2009. PMID: 20011514 Free PMC article.

5

In vitro and in vivo characterization of Lu AA41178: A novel, brain penetrant, pan-selective Kv7 potassium channel opener with efficacy in preclinical models of epileptic seizures and psychiatric disorders.

Grupe M, Bentzen BH, Benned-Jensen T, Nielsen V, Frederiksen K, Jensen HS, Jacobsen AM, Skibsbye L, Sams AG, Grunnet M, Rottländer M, Bastlund JF. Grupe M, et al. Eur J Pharmacol. 2020 Nov 15;887:173440. doi: 10.1016/j.ejphar.2020.173440. Epub 2020 Aug 1. Eur J Pharmacol. 2020. PMID: 32745603

6

The pan-Kv7 (KCNQ) Channel Opener Retigabine Inhibits Striatal Excitability by Direct Action on Striatal Neurons In Vivo.

Hansen HH, Weikop P, Mikkelsen MD, Rode F, Mikkelsen JD. Hansen HH, et al. Basic Clin Pharmacol Toxicol. 2017 Jan;120(1):46-51. doi: 10.1111/bcpt.12636. Epub 2016 Aug 23. Basic Clin Pharmacol Toxicol. 2017. PMID: 27377794 Free article.

7

Activation of Neuronal Voltage-Gated Potassium Kv7/KCNQ/M-Current by a Novel Channel Opener SCR2682 for Alleviation of Chronic Pain.

Wang J, Liu Y, Hu F, Yang J, Guo X, Hou X, Ju C, Wang K. Wang J, et al. J Pharmacol Exp Ther. 2021 Apr;377(1):20-28. doi: 10.1124/jpet.120.000357. Epub 2021 Jan 11. J Pharmacol Exp Ther. 2021. PMID: 33431609

8

Vascular KCNQ (Kv7) potassium channels as common signaling intermediates and therapeutic targets in cerebral vasospasm.

Mani BK, O'Dowd J, Kumar L, Brueggemann LI, Ross M, Byron KL. Mani BK, et al. J Cardiovasc Pharmacol. 2013 Jan;61(1):51-62. doi: 10.1097/FJC.0b013e3182771708. J Cardiovasc Pharmacol. 2013. PMID: 23107868 Free PMC article.

9

Sequence determinants of subtype-specific actions of KCNQ channel openers.

Wang AW, Yang R, Kurata HT. Wang AW, et al. J Physiol. 2017 Feb 1;595(3):663-676. doi: 10.1113/JP272762. Epub 2016 Sep 23. J Physiol. 2017. PMID: 27506413 Free PMC article.

10

Functional and behavioral signatures of Kv7 activator drug subtypes.

Kanyo R, Wang CK, Locskai LF, Li J, Allison WT, Kurata HT. Kanyo R, et al. Epilepsia. 2020 Aug;61(8):1678-1690. doi: 10.1111/epi.16592. Epub 2020 Jul 11. Epilepsia. 2020. PMID: 32652600

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