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Items: 1 to 20 of 133

1.

Co-opting the Fanconi anemia genomic stability pathway enables herpesvirus DNA synthesis and productive growth.

Karttunen H, Savas JN, McKinney C, Chen YH, Yates JR 3rd, Hukkanen V, Huang TT, Mohr I.

Mol Cell. 2014 Jul 3;55(1):111-22. doi: 10.1016/j.molcel.2014.05.020. Epub 2014 Jun 19.

2.

Patient-derived C-terminal mutation of FANCI causes protein mislocalization and reveals putative EDGE motif function in DNA repair.

Colnaghi L, Jones MJ, Cotto-Rios XM, Schindler D, Hanenberg H, Huang TT.

Blood. 2011 Feb 17;117(7):2247-56. doi: 10.1182/blood-2010-07-295758. Epub 2010 Oct 22.

3.

Fanconi anemia proteins FANCD2 and FANCI exhibit different DNA damage responses during S-phase.

Sareen A, Chaudhury I, Adams N, Sobeck A.

Nucleic Acids Res. 2012 Sep 1;40(17):8425-39. Epub 2012 Jun 29.

4.

[The role of the Fanconi anemia pathway in DNA repair and maintenance of genome stability].

Koczorowska AM, Białkowska A, Kluzek K, Zdzienicka MZ.

Postepy Hig Med Dosw (Online). 2014 May 8;68:459-72. doi: 10.5604/17322693.1101567. Review. Polish.

5.

FANCJ protein is important for the stability of FANCD2/FANCI proteins and protects them from proteasome and caspase-3 dependent degradation.

Clark DW, Tripathi K, Dorsman JC, Palle K.

Oncotarget. 2015 Oct 6;6(30):28816-32. doi: 10.18632/oncotarget.5006.

6.

The carboxyl terminus of FANCE recruits FANCD2 to the Fanconi Anemia (FA) E3 ligase complex to promote the FA DNA repair pathway.

Polito D, Cukras S, Wang X, Spence P, Moreau L, D'Andrea AD, Kee Y.

J Biol Chem. 2014 Mar 7;289(10):7003-10. doi: 10.1074/jbc.M113.533976. Epub 2014 Jan 22.

7.

Genomic instability in mice is greater in Fanconi anemia caused by deficiency of Fancd2 than Fancg.

Reliene R, Yamamoto ML, Rao PN, Schiestl RH.

Cancer Res. 2010 Dec 1;70(23):9703-10. doi: 10.1158/0008-5472.CAN-09-1022. Epub 2010 Nov 30.

8.

Coordinate nuclear targeting of the FANCD2 and FANCI proteins via a FANCD2 nuclear localization signal.

Boisvert RA, Rego MA, Azzinaro PA, Mauro M, Howlett NG.

PLoS One. 2013 Nov 21;8(11):e81387. doi: 10.1371/journal.pone.0081387. eCollection 2013.

9.

Physical and functional crosstalk between Fanconi anemia core components and the GINS replication complex.

Tumini E, Plevani P, Muzi-Falconi M, Marini F.

DNA Repair (Amst). 2011 Feb 7;10(2):149-58. doi: 10.1016/j.dnarep.2010.10.006. Epub 2010 Nov 24.

PMID:
21109493
10.

FANCI is a second monoubiquitinated member of the Fanconi anemia pathway.

Sims AE, Spiteri E, Sims RJ 3rd, Arita AG, Lach FP, Landers T, Wurm M, Freund M, Neveling K, Hanenberg H, Auerbach AD, Huang TT.

Nat Struct Mol Biol. 2007 Jun;14(6):564-7. Epub 2007 Apr 25.

PMID:
17460694
11.

Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair.

Smogorzewska A, Matsuoka S, Vinciguerra P, McDonald ER 3rd, Hurov KE, Luo J, Ballif BA, Gygi SP, Hofmann K, D'Andrea AD, Elledge SJ.

Cell. 2007 Apr 20;129(2):289-301. Epub 2007 Apr 5.

12.

The FANCD2-FANCI complex is recruited to DNA interstrand crosslinks before monoubiquitination of FANCD2.

Liang CC, Li Z, Lopez-Martinez D, Nicholson WV, Vénien-Bryan C, Cohn MA.

Nat Commun. 2016 Jul 13;7:12124. doi: 10.1038/ncomms12124.

13.

Regulation of the Fanconi anemia pathway by a CUE ubiquitin-binding domain in the FANCD2 protein.

Rego MA, Kolling FW 4th, Vuono EA, Mauro M, Howlett NG.

Blood. 2012 Sep 6;120(10):2109-17. doi: 10.1182/blood-2012-02-410472. Epub 2012 Jul 31.

14.

A novel role for Fanconi anemia (FA) pathway effector protein FANCD2 in cell cycle progression of untransformed primary human cells.

Song IY, Barkley LR, Day TA, Weiss RS, Vaziri C.

Cell Cycle. 2010 Jun 15;9(12):2375-88. Epub 2010 Jun 15.

PMID:
20519958
15.

The Fanconi anemia pathway is downregulated upon macrophage differentiation through two distinct mechanisms.

Lu WT, Lemonidis K, Drayton RM, Nouspikel T.

Cell Cycle. 2011 Oct 1;10(19):3300-10. doi: 10.4161/cc.10.19.17178. Epub 2011 Oct 1.

PMID:
21926477
16.

Ubiquitination-Linked Phosphorylation of the FANCI S/TQ Cluster Contributes to Activation of the Fanconi Anemia I/D2 Complex.

Cheung RS, Castella M, Abeyta A, Gafken PR, Tucker N, Taniguchi T.

Cell Rep. 2017 Jun 20;19(12):2432-2440. doi: 10.1016/j.celrep.2017.05.081.

17.

Ubiquitylation and the Fanconi anemia pathway.

Garner E, Smogorzewska A.

FEBS Lett. 2011 Sep 16;585(18):2853-60. doi: 10.1016/j.febslet.2011.04.078. Epub 2011 May 19. Review.

18.

High-risk human papillomavirus oncogenes disrupt the Fanconi anemia DNA repair pathway by impairing localization and de-ubiquitination of FancD2.

Khanal S, Galloway DA.

PLoS Pathog. 2019 Feb 28;15(2):e1007442. doi: 10.1371/journal.ppat.1007442. eCollection 2019 Feb.

19.

Regulation of the activation of the Fanconi anemia pathway by the p21 cyclin-dependent kinase inhibitor.

Rego MA, Harney JA, Mauro M, Shen M, Howlett NG.

Oncogene. 2012 Jan 19;31(3):366-75. doi: 10.1038/onc.2011.237. Epub 2011 Jun 20.

20.

The Fanconi anemia pathway promotes replication-dependent DNA interstrand cross-link repair.

Knipscheer P, Räschle M, Smogorzewska A, Enoiu M, Ho TV, Schärer OD, Elledge SJ, Walter JC.

Science. 2009 Dec 18;326(5960):1698-701. doi: 10.1126/science.1182372. Epub 2009 Nov 12.

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