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Items: 1 to 20 of 116

1.

In vivo RNA interference models of inducible and reversible Sirt1 knockdown in kidney cells.

Chuang PY, Xu J, Dai Y, Jia F, Mallipattu SK, Yacoub R, Gu L, Premsrirut PK, He JC.

Am J Pathol. 2014 Jul;184(7):1940-56. doi: 10.1016/j.ajpath.2014.03.016.

2.

Activation of peroxisome proliferator-activated receptor-γ coactivator 1α ameliorates mitochondrial dysfunction and protects podocytes from aldosterone-induced injury.

Yuan Y, Huang S, Wang W, Wang Y, Zhang P, Zhu C, Ding G, Liu B, Yang T, Zhang A.

Kidney Int. 2012 Oct;82(7):771-89. doi: 10.1038/ki.2012.188. Epub 2012 May 30.

PMID:
22648295
3.

Renal tubular Sirt1 attenuates diabetic albuminuria by epigenetically suppressing Claudin-1 overexpression in podocytes.

Hasegawa K, Wakino S, Simic P, Sakamaki Y, Minakuchi H, Fujimura K, Hosoya K, Komatsu M, Kaneko Y, Kanda T, Kubota E, Tokuyama H, Hayashi K, Guarente L, Itoh H.

Nat Med. 2013 Nov;19(11):1496-504. doi: 10.1038/nm.3363. Epub 2013 Oct 20.

4.

Alteration of forkhead box O (foxo4) acetylation mediates apoptosis of podocytes in diabetes mellitus.

Chuang PY, Dai Y, Liu R, He H, Kretzler M, Jim B, Cohen CD, He JC.

PLoS One. 2011;6(8):e23566. doi: 10.1371/journal.pone.0023566. Epub 2011 Aug 17.

6.

Endothelial mitochondrial oxidative stress determines podocyte depletion in segmental glomerulosclerosis.

Daehn I, Casalena G, Zhang T, Shi S, Fenninger F, Barasch N, Yu L, D'Agati V, Schlondorff D, Kriz W, Haraldsson B, Bottinger EP.

J Clin Invest. 2014 Apr;124(4):1608-21. doi: 10.1172/JCI71195. Epub 2014 Mar 3.

7.

Podocytes produce homeostatic chemokine stromal cell-derived factor-1/CXCL12, which contributes to glomerulosclerosis, podocyte loss and albuminuria in a mouse model of type 2 diabetes.

Sayyed SG, Hägele H, Kulkarni OP, Endlich K, Segerer S, Eulberg D, Klussmann S, Anders HJ.

Diabetologia. 2009 Nov;52(11):2445-54. doi: 10.1007/s00125-009-1493-6. Epub 2009 Aug 26.

PMID:
19707743
8.

Resolvin D1 protects podocytes in adriamycin-induced nephropathy through modulation of 14-3-3β acetylation.

Zhang X, Qu X, Sun YB, Caruana G, Bertram JF, Nikolic-Paterson DJ, Li J.

PLoS One. 2013 Jun 28;8(6):e67471. doi: 10.1371/journal.pone.0067471. Print 2013.

9.

Mpv17 in mitochondria protects podocytes against mitochondrial dysfunction and apoptosis in vivo and in vitro.

Casalena G, Krick S, Daehn I, Yu L, Ju W, Shi S, Tsai SY, D'Agati V, Lindenmeyer M, Cohen CD, Schlondorff D, Bottinger EP.

Am J Physiol Renal Physiol. 2014 Jun 1;306(11):F1372-80. doi: 10.1152/ajprenal.00608.2013. Epub 2014 Mar 5.

10.

Wnt/beta-catenin signaling promotes podocyte dysfunction and albuminuria.

Dai C, Stolz DB, Kiss LP, Monga SP, Holzman LB, Liu Y.

J Am Soc Nephrol. 2009 Sep;20(9):1997-2008. doi: 10.1681/ASN.2009010019. Epub 2009 Jul 23.

11.

Fn14 in podocytes and proteinuric kidney disease.

Sanchez-Niño MD, Poveda J, Sanz AB, Mezzano S, Carrasco S, Fernandez-Fernandez B, Burkly LC, Nair V, Kretzler M, Hodgin JB, Ruiz-Ortega M, Selgas R, Egido J, Ortiz A.

Biochim Biophys Acta. 2013 Dec;1832(12):2232-43. doi: 10.1016/j.bbadis.2013.08.010. Epub 2013 Aug 30.

12.

Valsartan slows the progression of diabetic nephropathy in db/db mice via a reduction in podocyte injury, and renal oxidative stress and inflammation.

Zhou G, Cheung AK, Liu X, Huang Y.

Clin Sci (Lond). 2014 May;126(10):707-20. doi: 10.1042/CS20130223.

PMID:
24195695
13.

Kidney-specific overexpression of Sirt1 protects against acute kidney injury by retaining peroxisome function.

Hasegawa K, Wakino S, Yoshioka K, Tatematsu S, Hara Y, Minakuchi H, Sueyasu K, Washida N, Tokuyama H, Tzukerman M, Skorecki K, Hayashi K, Itoh H.

J Biol Chem. 2010 Apr 23;285(17):13045-56. doi: 10.1074/jbc.M109.067728. Epub 2010 Feb 5.

14.

Ret is critical for podocyte survival following glomerular injury in vivo.

Hou G, Wu V, Singh G, Holzman LB, Tsui CC.

Am J Physiol Renal Physiol. 2015 Apr 1;308(7):F774-83. doi: 10.1152/ajprenal.00483.2014. Epub 2015 Jan 13.

15.

Smad3/Nox4-mediated mitochondrial dysfunction plays a crucial role in puromycin aminonucleoside-induced podocyte damage.

Yu L, Liu Y, Wu Y, Liu Q, Feng J, Gu X, Xiong Y, Fan Q, Ye J.

Cell Signal. 2014 Dec;26(12):2979-91. doi: 10.1016/j.cellsig.2014.08.030. Epub 2014 Sep 16.

PMID:
25229402
16.

Lack of {alpha}8-integrin aggravates podocyte injury in experimental diabetic nephropathy.

Hartner A, Cordasic N, Menendez-Castro C, Volkert G, Yabu JM, Kupraszewicz-Hutzler M, Rascher W, Hilgers KF.

Am J Physiol Renal Physiol. 2010 Nov;299(5):F1151-7. doi: 10.1152/ajprenal.00058.2010. Epub 2010 Sep 8.

17.

beta-Catenin mediates adriamycin-induced albuminuria and podocyte injury in adult mouse kidneys.

Heikkilä E, Juhila J, Lassila M, Messing M, Perälä N, Lehtonen E, Lehtonen S, Sjef Verbeek J, Holthofer H.

Nephrol Dial Transplant. 2010 Aug;25(8):2437-46. doi: 10.1093/ndt/gfq076. Epub 2010 Mar 17.

18.

Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney.

Kume S, Uzu T, Horiike K, Chin-Kanasaki M, Isshiki K, Araki S, Sugimoto T, Haneda M, Kashiwagi A, Koya D.

J Clin Invest. 2010 Apr;120(4):1043-55. doi: 10.1172/JCI41376. Epub 2010 Mar 24.

19.

CDK inhibitor p21 is prosurvival in adriamycin-induced podocyte injury, in vitro and in vivo.

Marshall CB, Krofft RD, Pippin JW, Shankland SJ.

Am J Physiol Renal Physiol. 2010 May;298(5):F1140-51. doi: 10.1152/ajprenal.00216.2009. Epub 2010 Feb 3.

20.

Glomerular endothelial cell injury and damage precedes that of podocytes in adriamycin-induced nephropathy.

Sun YB, Qu X, Zhang X, Caruana G, Bertram JF, Li J.

PLoS One. 2013;8(1):e55027. doi: 10.1371/journal.pone.0055027. Epub 2013 Jan 24.

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