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Items: 1 to 20 of 1129

1.

Phenethyl isothiocyanate induces DNA damage-associated G2/M arrest and subsequent apoptosis in oral cancer cells with varying p53 mutations.

Yeh YT, Yeh H, Su SH, Lin JS, Lee KJ, Shyu HW, Chen ZF, Huang SY, Su SJ.

Free Radic Biol Med. 2014 Sep;74:1-13. doi: 10.1016/j.freeradbiomed.2014.06.008. Epub 2014 Jun 19.

PMID:
24952138
2.

Benzyl isothiocyanate promotes apoptosis of oral cancer cells via an acute redox stress-mediated DNA damage response.

Yeh YT, Hsu YN, Huang SY, Lin JS, Chen ZF, Chow NH, Su SH, Shyu HW, Lin CC, Huang WT, Yeh H, Chih YC, Huang YH, Su SJ.

Food Chem Toxicol. 2016 Nov;97:336-345. doi: 10.1016/j.fct.2016.09.028. Epub 2016 Sep 28.

PMID:
27693243
3.
4.

Phenethyl isothiocyanate triggers apoptosis in human malignant melanoma A375.S2 cells through reactive oxygen species and the mitochondria-dependent pathways.

Huang SH, Hsu MH, Hsu SC, Yang JS, Huang WW, Huang AC, Hsiao YP, Yu CC, Chung JG.

Hum Exp Toxicol. 2014 Mar;33(3):270-83. doi: 10.1177/0960327113491508. Epub 2013 Jun 11.

PMID:
23760257
5.

Phenethyl isothiocyanate (PEITC) promotes G2/M phase arrest via p53 expression and induces apoptosis through caspase- and mitochondria-dependent signaling pathways in human prostate cancer DU 145 cells.

Tang NY, Huang YT, Yu CS, Ko YC, Wu SH, Ji BC, Yang JS, Yang JL, Hsia TC, Chen YY, Chung JG.

Anticancer Res. 2011 May;31(5):1691-702.

PMID:
21617228
7.
8.

Benzyl isothiocyanate (BITC) induces G2/M phase arrest and apoptosis in human melanoma A375.S2 cells through reactive oxygen species (ROS) and both mitochondria-dependent and death receptor-mediated multiple signaling pathways.

Huang SH, Wu LW, Huang AC, Yu CC, Lien JC, Huang YP, Yang JS, Yang JH, Hsiao YP, Wood WG, Yu CS, Chung JG.

J Agric Food Chem. 2012 Jan 18;60(2):665-75. doi: 10.1021/jf204193v. Epub 2012 Jan 6.

PMID:
22148415
9.

Sterigmatocystin-induced DNA damage triggers G2 arrest via an ATM/p53-related pathway in human gastric epithelium GES-1 cells in vitro.

Zhang D, Cui Y, Shen H, Xing L, Cui J, Wang J, Zhang X.

PLoS One. 2013 May 21;8(5):e65044. doi: 10.1371/journal.pone.0065044. Print 2013.

PMID:
23705030
10.

Non-thermal atmospheric pressure plasma induces apoptosis in oral cavity squamous cell carcinoma: Involvement of DNA-damage-triggering sub-G(1) arrest via the ATM/p53 pathway.

Chang JW, Kang SU, Shin YS, Kim KI, Seo SJ, Yang SS, Lee JS, Moon E, Baek SJ, Lee K, Kim CH.

Arch Biochem Biophys. 2014 Mar 1;545:133-40. doi: 10.1016/j.abb.2014.01.022. Epub 2014 Jan 29.

PMID:
24486404
11.

Phenethyl isothiocyanate induces calcium mobilization and mitochondrial cell death pathway in cholangiocarcinoma KKU-M214 cells.

Tusskorn O, Senggunprai L, Prawan A, Kukongviriyapan U, Kukongviriyapan V.

BMC Cancer. 2013 Dec 5;13:571. doi: 10.1186/1471-2407-13-571.

PMID:
24304591
12.

Phenethyl isothiocyanate induced apoptosis via down regulation of Bcl-2/XIAP and triggering of the mitochondrial pathway in MCF-7 cells.

Lee JW, Cho MK.

Arch Pharm Res. 2008 Dec;31(12):1604-12. doi: 10.1007/s12272-001-2158-2. Epub 2008 Dec 20.

PMID:
19099231
13.

Anti-tumor effect of germacrone on human hepatoma cell lines through inducing G2/M cell cycle arrest and promoting apoptosis.

Liu Y, Wang W, Fang B, Ma F, Zheng Q, Deng P, Zhao S, Chen M, Yang G, He G.

Eur J Pharmacol. 2013 Jan 5;698(1-3):95-102. doi: 10.1016/j.ejphar.2012.10.013. Epub 2012 Oct 29.

PMID:
23117090
14.

2-Hydroxyethyl methacrylate-induced apoptosis through the ATM- and p53-dependent intrinsic mitochondrial pathway.

Schweikl H, Petzel C, Bolay C, Hiller KA, Buchalla W, Krifka S.

Biomaterials. 2014 Mar;35(9):2890-904. doi: 10.1016/j.biomaterials.2013.12.044. Epub 2014 Jan 8.

PMID:
24411679
15.

The dietary phytochemical 3,3'-diindolylmethane induces G2/M arrest and apoptosis in oral squamous cell carcinoma by modulating Akt-NF-κB, MAPK, and p53 signaling.

Weng JR, Bai LY, Chiu CF, Wang YC, Tsai MH.

Chem Biol Interact. 2012 Feb 5;195(3):224-30. doi: 10.1016/j.cbi.2012.01.003. Epub 2012 Jan 24.

PMID:
22290291
16.

Caspase-dependent apoptosis induction by phenethyl isothiocyanate, a cruciferous vegetable-derived cancer chemopreventive agent, is mediated by Bak and Bax.

Xiao D, Zeng Y, Choi S, Lew KL, Nelson JB, Singh SV.

Clin Cancer Res. 2005 Apr 1;11(7):2670-9.

PMID:
15814648
17.

Phenethyl isothiocyanate-induced apoptosis in PC-3 human prostate cancer cells is mediated by reactive oxygen species-dependent disruption of the mitochondrial membrane potential.

Xiao D, Lew KL, Zeng Y, Xiao H, Marynowski SW, Dhir R, Singh SV.

Carcinogenesis. 2006 Nov;27(11):2223-34. Epub 2006 Jun 13.

PMID:
16774948
18.

Decitabine, a DNA methyltransferases inhibitor, induces cell cycle arrest at G2/M phase through p53-independent pathway in human cancer cells.

Shin DY, Sung Kang H, Kim GY, Kim WJ, Yoo YH, Choi YH.

Biomed Pharmacother. 2013 May;67(4):305-11. doi: 10.1016/j.biopha.2013.01.004. Epub 2013 Feb 14.

PMID:
23582784
19.

Phenethyl isothiocyanate suppresses EGF-stimulated SAS human oral squamous carcinoma cell invasion by targeting EGF receptor signaling.

Chen HJ, Lin CM, Lee CY, Shih NC, Amagaya S, Lin YC, Yang JS.

Int J Oncol. 2013 Aug;43(2):629-37. doi: 10.3892/ijo.2013.1977. Epub 2013 Jun 7.

PMID:
23754208
20.

Oxidative DNA damage is involved in ochratoxin A-induced G2 arrest through ataxia telangiectasia-mutated (ATM) pathways in human gastric epithelium GES-1 cells in vitro.

Cui J, Liu J, Wu S, Wang Y, Shen H, Xing L, Wang J, Yan X, Zhang X.

Arch Toxicol. 2013 Oct;87(10):1829-40. doi: 10.1007/s00204-013-1043-3. Epub 2013 Mar 21.

PMID:
23515941

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