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Items: 1 to 20 of 173

1.

Neurofibromin inactivation impairs osteocyte development in Nf1Prx1 and Nf1Col1 mouse models.

Kühnisch J, Seto J, Lange C, Stumpp S, Kobus K, Grohmann J, Elefteriou F, Fratzl P, Mundlos S, Kolanczyk M.

Bone. 2014 Sep;66:155-62. doi: 10.1016/j.bone.2014.06.012. Epub 2014 Jun 17.

PMID:
24947449
2.

Multiscale, converging defects of macro-porosity, microstructure and matrix mineralization impact long bone fragility in NF1.

Kühnisch J, Seto J, Lange C, Schrof S, Stumpp S, Kobus K, Grohmann J, Kossler N, Varga P, Osswald M, Emmerich D, Tinschert S, Thielemann F, Duda G, Seifert W, El Khassawna T, Stevenson DA, Elefteriou F, Kornak U, Raum K, Fratzl P, Mundlos S, Kolanczyk M.

PLoS One. 2014 Jan 21;9(1):e86115. doi: 10.1371/journal.pone.0086115. eCollection 2014.

3.

Targeted Disruption of NF1 in Osteocytes Increases FGF23 and Osteoid With Osteomalacia-like Bone Phenotype.

Kamiya N, Yamaguchi R, Aruwajoye O, Kim AJ, Kuroyanagi G, Phipps M, Adapala NS, Feng JQ, Kim HK.

J Bone Miner Res. 2017 Aug;32(8):1716-1726. doi: 10.1002/jbmr.3155. Epub 2017 May 23.

PMID:
28425622
4.

Evidence that osteocyte perilacunar remodelling contributes to polyethylene wear particle induced osteolysis.

Ormsby RT, Cantley M, Kogawa M, Solomon LB, Haynes DR, Findlay DM, Atkins GJ.

Acta Biomater. 2016 Mar;33:242-51. doi: 10.1016/j.actbio.2016.01.016. Epub 2016 Jan 18.

PMID:
26796208
5.

Modelling neurofibromatosis type 1 tibial dysplasia and its treatment with lovastatin.

Kolanczyk M, Kühnisch J, Kossler N, Osswald M, Stumpp S, Thurisch B, Kornak U, Mundlos S.

BMC Med. 2008 Jul 31;6:21. doi: 10.1186/1741-7015-6-21.

6.

Distinct roles for intrinsic osteocyte abnormalities and systemic factors in regulation of FGF23 and bone mineralization in Hyp mice.

Liu S, Tang W, Zhou J, Vierthaler L, Quarles LD.

Am J Physiol Endocrinol Metab. 2007 Dec;293(6):E1636-44. Epub 2007 Sep 11.

7.

Double NF1 inactivation affects adrenocortical function in NF1Prx1 mice and a human patient.

Kobus K, Hartl D, Ott CE, Osswald M, Huebner A, von der Hagen M, Emmerich D, Kühnisch J, Morreau H, Hes FJ, Mautner VF, Harder A, Tinschert S, Mundlos S, Kolanczyk M.

PLoS One. 2015 Mar 16;10(3):e0119030. doi: 10.1371/journal.pone.0119030. eCollection 2015.

8.

Overexpression of Bcl2 in osteoblasts inhibits osteoblast differentiation and induces osteocyte apoptosis.

Moriishi T, Maruyama Z, Fukuyama R, Ito M, Miyazaki T, Kitaura H, Ohnishi H, Furuichi T, Kawai Y, Masuyama R, Komori H, Takada K, Kawaguchi H, Komori T.

PLoS One. 2011;6(11):e27487. doi: 10.1371/journal.pone.0027487. Epub 2011 Nov 17.

9.

Matrix metalloproteinase-13 is required for osteocytic perilacunar remodeling and maintains bone fracture resistance.

Tang SY, Herber RP, Ho SP, Alliston T.

J Bone Miner Res. 2012 Sep;27(9):1936-50. doi: 10.1002/jbmr.1646.

10.

NF1 is a critical regulator of muscle development and metabolism.

Sullivan K, El-Hoss J, Quinlan KG, Deo N, Garton F, Seto JT, Gdalevitch M, Turner N, Cooney GJ, Kolanczyk M, North KN, Little DG, Schindeler A.

Hum Mol Genet. 2014 Mar 1;23(5):1250-9. doi: 10.1093/hmg/ddt515. Epub 2013 Oct 24.

11.

Osteoblast migration into type I collagen gel and differentiation to osteocyte-like cells within a self-produced mineralized matrix: a novel system for analyzing differentiation from osteoblast to osteocyte.

Uchihashi K, Aoki S, Matsunobu A, Toda S.

Bone. 2013 Jan;52(1):102-10. doi: 10.1016/j.bone.2012.09.001. Epub 2012 Sep 14. Erratum in: Bone. 2013 Sep;56(1):227. Dosage error in article text.

PMID:
22985890
12.

Human primary osteocyte differentiation in a 3D culture system.

Boukhechba F, Balaguer T, Michiels JF, Ackermann K, Quincey D, Bouler JM, Pyerin W, Carle GF, Rochet N.

J Bone Miner Res. 2009 Nov;24(11):1927-35. doi: 10.1359/jbmr.090517.

13.

Vitamin D regulates osteocyte survival and perilacunar remodeling in human and murine bone.

Rolvien T, Krause M, Jeschke A, Yorgan T, Püschel K, Schinke T, Busse B, Demay MB, Amling M.

Bone. 2017 Oct;103:78-87. doi: 10.1016/j.bone.2017.06.022. Epub 2017 Jun 27.

PMID:
28666969
14.

Dentin matrix protein 1 gene cis-regulation: use in osteocytes to characterize local responses to mechanical loading in vitro and in vivo.

Yang W, Lu Y, Kalajzic I, Guo D, Harris MA, Gluhak-Heinrich J, Kotha S, Bonewald LF, Feng JQ, Rowe DW, Turner CH, Robling AG, Harris SE.

J Biol Chem. 2005 May 27;280(21):20680-90. Epub 2005 Feb 22.

15.

Osteocyte apoptosis is induced by weightlessness in mice and precedes osteoclast recruitment and bone loss.

Aguirre JI, Plotkin LI, Stewart SA, Weinstein RS, Parfitt AM, Manolagas SC, Bellido T.

J Bone Miner Res. 2006 Apr;21(4):605-15. Epub 2006 Apr 5.

16.

Impact of extracellular matrix derived from osteoarthritis subchondral bone osteoblasts on osteocytes: role of integrinβ1 and focal adhesion kinase signaling cues.

Prasadam I, Farnaghi S, Feng JQ, Gu W, Perry S, Crawford R, Xiao Y.

Arthritis Res Ther. 2013 Oct 9;15(5):R150. doi: 10.1186/ar4333.

17.

Cell autonomous requirement of connexin 43 for osteocyte survival: consequences for endocortical resorption and periosteal bone formation.

Bivi N, Condon KW, Allen MR, Farlow N, Passeri G, Brun LR, Rhee Y, Bellido T, Plotkin LI.

J Bone Miner Res. 2012 Feb;27(2):374-89. doi: 10.1002/jbmr.548.

18.

Down-regulation of expression of osteoblast and osteocyte markers in periodontal tissues associated with the spontaneous alveolar bone loss of interleukin-10 knockout mice.

Claudino M, Garlet TP, Cardoso CR, de Assis GF, Taga R, Cunha FQ, Silva JS, Garlet GP.

Eur J Oral Sci. 2010 Feb;118(1):19-28. doi: 10.1111/j.1600-0722.2009.00706.x.

PMID:
20156261
19.

Hyperactive Ras/MAPK signaling is critical for tibial nonunion fracture in neurofibromin-deficient mice.

Sharma R, Wu X, Rhodes SD, Chen S, He Y, Yuan J, Li J, Yang X, Li X, Jiang L, Kim ET, Stevenson DA, Viskochil D, Xu M, Yang FC.

Hum Mol Genet. 2013 Dec 1;22(23):4818-28. doi: 10.1093/hmg/ddt333. Epub 2013 Jul 17.

20.

Extracellular matrix mineralization promotes E11/gp38 glycoprotein expression and drives osteocytic differentiation.

Prideaux M, Loveridge N, Pitsillides AA, Farquharson C.

PLoS One. 2012;7(5):e36786. doi: 10.1371/journal.pone.0036786. Epub 2012 May 7.

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