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Items: 1 to 20 of 117

1.

Neuropathic plasticity in the opioid and non-opioid actions of dynorphin A fragments and their interactions with bradykinin B2 receptors on neuronal activity in the rat spinal cord.

Bannister K, Lee YS, Goncalves L, Porreca F, Lai J, Dickenson AH.

Neuropharmacology. 2014 Oct;85:375-83. doi: 10.1016/j.neuropharm.2014.06.005. Epub 2014 Jun 14.

2.

Pronociceptive actions of dynorphin maintain chronic neuropathic pain.

Wang Z, Gardell LR, Ossipov MH, Vanderah TW, Brennan MB, Hochgeschwender U, Hruby VJ, Malan TP Jr, Lai J, Porreca F.

J Neurosci. 2001 Mar 1;21(5):1779-86.

3.

Dynorphin A activates bradykinin receptors to maintain neuropathic pain.

Lai J, Luo MC, Chen Q, Ma S, Gardell LR, Ossipov MH, Porreca F.

Nat Neurosci. 2006 Dec;9(12):1534-40. Epub 2006 Nov 19.

PMID:
17115041
4.

Neuropathic pain activates the endogenous kappa opioid system in mouse spinal cord and induces opioid receptor tolerance.

Xu M, Petraschka M, McLaughlin JP, Westenbroek RE, Caron MG, Lefkowitz RJ, Czyzyk TA, Pintar JE, Terman GW, Chavkin C.

J Neurosci. 2004 May 12;24(19):4576-84.

5.

Sustained morphine exposure induces a spinal dynorphin-dependent enhancement of excitatory transmitter release from primary afferent fibers.

Gardell LR, Wang R, Burgess SE, Ossipov MH, Vanderah TW, Malan TP Jr, Lai J, Porreca F.

J Neurosci. 2002 Aug 1;22(15):6747-55.

7.

Spinal dynorphin and bradykinin receptors maintain inflammatory hyperalgesia.

Luo MC, Chen Q, Ossipov MH, Rankin DR, Porreca F, Lai J.

J Pain. 2008 Dec;9(12):1096-105. doi: 10.1016/j.jpain.2008.06.005. Epub 2008 Oct 31.

8.

Enhanced evoked excitatory transmitter release in experimental neuropathy requires descending facilitation.

Gardell LR, Vanderah TW, Gardell SE, Wang R, Ossipov MH, Lai J, Porreca F.

J Neurosci. 2003 Sep 10;23(23):8370-9.

9.

Contribution and interaction of kinin receptors and dynorphin A in a model of trigeminal neuropathic pain in mice.

Luiz AP, Schroeder SD, Rae GA, Calixto JB, Chichorro JG.

Neuroscience. 2015 Aug 6;300:189-200. doi: 10.1016/j.neuroscience.2015.05.015. Epub 2015 May 14.

PMID:
25982562
10.

Discovery of amphipathic dynorphin A analogues to inhibit the neuroexcitatory effects of dynorphin A through bradykinin receptors in the spinal cord.

Lee YS, Muthu D, Hall SM, Ramos-Colon C, Rankin D, Hu J, Sandweiss AJ, De Felice M, Xie JY, Vanderah TW, Porreca F, Lai J, Hruby VJ.

J Am Chem Soc. 2014 May 7;136(18):6608-16. doi: 10.1021/ja501677q. Epub 2014 Apr 29.

11.

Minocycline prevents dynorphin-induced neurotoxicity during neuropathic pain in rats.

Rojewska E, Makuch W, Przewlocka B, Mika J.

Neuropharmacology. 2014 Nov;86:301-10. doi: 10.1016/j.neuropharm.2014.08.001. Epub 2014 Aug 27.

12.

Extraterritorial neuropathic pain correlates with multisegmental elevation of spinal dynorphin in nerve-injured rats.

Malan TP, Ossipov MH, Gardell LR, Ibrahim M, Bian D, Lai J, Porreca F.

Pain. 2000 May;86(1-2):185-94.

PMID:
10779675
13.
14.

Cyclic non-opioid dynorphin A analogues for the bradykinin receptors.

Lee YS, Remesic M, Ramos-Colon C, Hall SM, Kuzmin A, Rankin D, Porreca F, Lai J, Hruby VJ.

Bioorg Med Chem Lett. 2016 Nov 15;26(22):5513-5516. doi: 10.1016/j.bmcl.2016.10.010. Epub 2016 Oct 6.

PMID:
27756562
16.

Activation of spinal and supraspinal cannabinoid-1 receptors leads to antinociception in a rat model of neuropathic spinal cord injury pain.

Hama A, Sagen J.

Brain Res. 2011 Sep 15;1412:44-54. doi: 10.1016/j.brainres.2011.07.031. Epub 2011 Jul 26.

17.

Intrathecal carbenoxolone inhibits neuropathic pain and spinal wide-dynamic range neuronal activity in rats after an L5 spinal nerve injury.

Xu Q, Cheong YK, Yang F, Tiwari V, Li J, Liu J, Raja SN, Li W, Guan Y.

Neurosci Lett. 2014 Mar 20;563:45-50. doi: 10.1016/j.neulet.2014.01.042. Epub 2014 Jan 31.

18.

Attenuation of persistent experimental pancreatitis pain by a bradykinin b2 receptor antagonist.

Chen Q, Vera-Portocarrero LP, Ossipov MH, Vardanyan M, Lai J, Porreca F.

Pancreas. 2010 Nov;39(8):1220-5. doi: 10.1097/MPA.0b013e3181df1c90.

PMID:
20531238
19.

Dynorphin promotes abnormal pain and spinal opioid antinociceptive tolerance.

Vanderah TW, Gardell LR, Burgess SE, Ibrahim M, Dogrul A, Zhong CM, Zhang ET, Malan TP Jr, Ossipov MH, Lai J, Porreca F.

J Neurosci. 2000 Sep 15;20(18):7074-9.

20.

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