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Items: 1 to 20 of 119

1.

The parasitophorous vacuole membrane of Toxoplasma gondii is targeted for disruption by ubiquitin-like conjugation systems of autophagy.

Choi J, Park S, Biering SB, Selleck E, Liu CY, Zhang X, Fujita N, Saitoh T, Akira S, Yoshimori T, Sibley LD, Hwang S, Virgin HW.

Immunity. 2014 Jun 19;40(6):924-35. doi: 10.1016/j.immuni.2014.05.006. Epub 2014 Jun 12.

2.

Targeting by AutophaGy proteins (TAG): Targeting of IFNG-inducible GTPases to membranes by the LC3 conjugation system of autophagy.

Park S, Choi J, Biering SB, Dominici E, Williams LE, Hwang S.

Autophagy. 2016 Jul 2;12(7):1153-67. doi: 10.1080/15548627.2016.1178447. Epub 2016 May 12.

3.

Role of mouse and human autophagy proteins in IFN-γ-induced cell-autonomous responses against Toxoplasma gondii.

Ohshima J, Lee Y, Sasai M, Saitoh T, Su Ma J, Kamiyama N, Matsuura Y, Pann-Ghill S, Hayashi M, Ebisu S, Takeda K, Akira S, Yamamoto M.

J Immunol. 2014 Apr 1;192(7):3328-35. doi: 10.4049/jimmunol.1302822. Epub 2014 Feb 21.

4.

Autophagosome-independent essential function for the autophagy protein Atg5 in cellular immunity to intracellular pathogens.

Zhao Z, Fux B, Goodwin M, Dunay IR, Strong D, Miller BC, Cadwell K, Delgado MA, Ponpuak M, Green KG, Schmidt RE, Mizushima N, Deretic V, Sibley LD, Virgin HW.

Cell Host Microbe. 2008 Nov 13;4(5):458-69. doi: 10.1016/j.chom.2008.10.003.

5.

The E2-like conjugation enzyme Atg3 promotes binding of IRG and Gbp proteins to Chlamydia- and Toxoplasma-containing vacuoles and host resistance.

Haldar AK, Piro AS, Pilla DM, Yamamoto M, Coers J.

PLoS One. 2014 Jan 17;9(1):e86684. doi: 10.1371/journal.pone.0086684. eCollection 2014.

6.

Host cell autophagy is induced by Toxoplasma gondii and contributes to parasite growth.

Wang Y, Weiss LM, Orlofsky A.

J Biol Chem. 2009 Jan 16;284(3):1694-701. doi: 10.1074/jbc.M807890200. Epub 2008 Nov 21.

7.

Structure of the human ATG12~ATG5 conjugate required for LC3 lipidation in autophagy.

Otomo C, Metlagel Z, Takaesu G, Otomo T.

Nat Struct Mol Biol. 2013 Jan;20(1):59-66. doi: 10.1038/nsmb.2431. Epub 2012 Dec 2.

8.

A Noncanonical Autophagy Pathway Restricts Toxoplasma gondii Growth in a Strain-Specific Manner in IFN-γ-Activated Human Cells.

Selleck EM, Orchard RC, Lassen KG, Beatty WL, Xavier RJ, Levine B, Virgin HW, Sibley LD.

MBio. 2015 Sep 8;6(5):e01157-15. doi: 10.1128/mBio.01157-15.

9.

Vaccinia virus leads to ATG12–ATG3 conjugation and deficiency in autophagosome formation.

Moloughney JG, Monken CE, Tao H, Zhang H, Thomas JD, Lattime EC, Jin S.

Autophagy. 2011 Dec;7(12):1434-47.

10.

CD40 induces macrophage anti-Toxoplasma gondii activity by triggering autophagy-dependent fusion of pathogen-containing vacuoles and lysosomes.

Andrade RM, Wessendarp M, Gubbels MJ, Striepen B, Subauste CS.

J Clin Invest. 2006 Sep;116(9):2366-77.

11.

K63-Linked Ubiquitination Targets Toxoplasma gondii for Endo-lysosomal Destruction in IFNγ-Stimulated Human Cells.

Clough B, Wright JD, Pereira PM, Hirst EM, Johnston AC, Henriques R, Frickel EM.

PLoS Pathog. 2016 Nov 22;12(11):e1006027. doi: 10.1371/journal.ppat.1006027. eCollection 2016 Nov.

12.

The FAP motif within human ATG7, an autophagy-related E1-like enzyme, is essential for the E2-substrate reaction of LC3 lipidation.

Tanida I, Yamasaki M, Komatsu M, Ueno T.

Autophagy. 2012 Jan;8(1):88-97. doi: 10.4161/auto.8.1.18339. Epub 2012 Jan 1.

PMID:
22170151
13.

Autophagy in immunity against Toxoplasma gondii.

Subauste CS.

Curr Top Microbiol Immunol. 2009;335:251-65. doi: 10.1007/978-3-642-00302-8_12. Review.

PMID:
19802569
14.

Toxoplasma gondii-induced activation of EGFR prevents autophagy protein-mediated killing of the parasite.

Muniz-Feliciano L, Van Grol J, Portillo JA, Liew L, Liu B, Carlin CR, Carruthers VB, Matthews S, Subauste CS.

PLoS Pathog. 2013;9(12):e1003809. doi: 10.1371/journal.ppat.1003809. Epub 2013 Dec 19.

15.

ATG12 conjugation to ATG3 regulates mitochondrial homeostasis and cell death.

Radoshevich L, Murrow L, Chen N, Fernandez E, Roy S, Fung C, Debnath J.

Cell. 2010 Aug 20;142(4):590-600. doi: 10.1016/j.cell.2010.07.018.

16.

Guanylate-binding protein 1 (Gbp1) contributes to cell-autonomous immunity against Toxoplasma gondii.

Selleck EM, Fentress SJ, Beatty WL, Degrandi D, Pfeffer K, Virgin HW 4th, Macmicking JD, Sibley LD.

PLoS Pathog. 2013;9(4):e1003320. doi: 10.1371/journal.ppat.1003320. Epub 2013 Apr 25.

17.

Stimulation of ATG12-ATG5 conjugation by ribonucleic acid.

Shao Y, Gao Z, Feldman T, Jiang X.

Autophagy. 2007 Jan-Feb;3(1):10-6. Epub 2007 Jan 27.

PMID:
16963840
18.

Essential role for GABARAP autophagy proteins in interferon-inducible GTPase-mediated host defense.

Sasai M, Sakaguchi N, Ma JS, Nakamura S, Kawabata T, Bando H, Lee Y, Saitoh T, Akira S, Iwasaki A, Standley DM, Yoshimori T, Yamamoto M.

Nat Immunol. 2017 Aug;18(8):899-910. doi: 10.1038/ni.3767. Epub 2017 Jun 12.

PMID:
28604719
19.

Nondegradative role of Atg5-Atg12/ Atg16L1 autophagy protein complex in antiviral activity of interferon gamma.

Hwang S, Maloney NS, Bruinsma MW, Goel G, Duan E, Zhang L, Shrestha B, Diamond MS, Dani A, Sosnovtsev SV, Green KY, Lopez-Otin C, Xavier RJ, Thackray LB, Virgin HW.

Cell Host Microbe. 2012 Apr 19;11(4):397-409. doi: 10.1016/j.chom.2012.03.002.

20.

Autophagy-related protein 8 (Atg8) family interacting motif in Atg3 mediates the Atg3-Atg8 interaction and is crucial for the cytoplasm-to-vacuole targeting pathway.

Yamaguchi M, Noda NN, Nakatogawa H, Kumeta H, Ohsumi Y, Inagaki F.

J Biol Chem. 2010 Sep 17;285(38):29599-607. doi: 10.1074/jbc.M110.113670. Epub 2010 Jul 8.

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