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Increased visceral adiposity and cortisol to cortisone ratio in adults with congenital lifetime isolated GH deficiency.

Gomes-Santos E, Salvatori R, Ferrão TO, Oliveira CR, Diniz RD, Santana JA, Pereira FA, Barbosa RA, Souza AH, Melo EV, Epitácio-Pereira CC, Oliveira-Santos AA, Oliveira IA, Machado JA, Santana-Júnior FJ, Barreto-Filho JA, Aguiar-Oliveira MH.

J Clin Endocrinol Metab. 2014 Sep;99(9):3285-9. doi: 10.1210/jc.2014-2132. Epub 2014 Jun 13.


Epicardial fat thickness significantly decreases after short-term growth hormone (GH) replacement therapy in adults with GH deficiency.

Ferrante E, Malavazos AE, Giavoli C, Ermetici F, Coman C, Bergamaschi S, Profka E, Briganti S, Ronchi CL, Passeri E, Corbetta S, Lania AG, Spada A, Iacobellis G, Ambrosi B, Beck-Peccoz P.

Nutr Metab Cardiovasc Dis. 2013 May;23(5):459-65. doi: 10.1016/j.numecd.2011.09.001. Epub 2011 Nov 25.


Lower growth hormone and higher cortisol are associated with greater visceral adiposity, intramyocellular lipids, and insulin resistance in overweight girls.

Misra M, Bredella MA, Tsai P, Mendes N, Miller KK, Klibanski A.

Am J Physiol Endocrinol Metab. 2008 Aug;295(2):E385-92. doi: 10.1152/ajpendo.00052.2008. Epub 2008 Jun 10.


Cortisol metabolism in human obesity: impaired cortisone-->cortisol conversion in subjects with central adiposity.

Stewart PM, Boulton A, Kumar S, Clark PM, Shackleton CH.

J Clin Endocrinol Metab. 1999 Mar;84(3):1022-7.


Isolated GH deficiency due to a GHRH receptor mutation causes hip joint problems and genu valgum, and reduces size but not density of trabecular and mixed bone.

Epitácio-Pereira CC, Silva GM, Salvatori R, Santana JA, Pereira FA, Gois-Junior MB, Britto AV, Oliveira CR, Souza AH, Santos EG, Campos VC, Pereira RM, Valença EH, Barbosa RA, Farias MI, de Paula FJ, Ribeiro TV, Oliveira MC, Aguiar-Oliveira MH.

J Clin Endocrinol Metab. 2013 Nov;98(11):E1710-5. doi: 10.1210/jc.2013-2349. Epub 2013 Sep 20.


Body fat distribution and cortisol metabolism in healthy men: enhanced 5beta-reductase and lower cortisol/cortisone metabolite ratios in men with fatty liver.

Westerbacka J, Yki-Järvinen H, Vehkavaara S, Häkkinen AM, Andrew R, Wake DJ, Seckl JR, Walker BR.

J Clin Endocrinol Metab. 2003 Oct;88(10):4924-31.


Retesting young adults with childhood-onset growth hormone (GH) deficiency with GH-releasing-hormone-plus-arginine test.

Aimaretti G, Baffoni C, Bellone S, Di Vito L, Corneli G, Arvat E, Benso L, Camanni F, Ghigo E.

J Clin Endocrinol Metab. 2000 Oct;85(10):3693-9.


Associations of visceral adiposity and exercise participation with C-reactive protein, insulin resistance, and endothelial dysfunction in Korean healthy adults.

Kim K, Valentine RJ, Shin Y, Gong K.

Metabolism. 2008 Sep;57(9):1181-9. doi: 10.1016/j.metabol.2008.04.009.


Gender differences in GH response to GHRH+ARG in lipodystrophic patients with HIV: a key role for body fat distribution.

Brigante G, Diazzi C, Ansaloni A, Zirilli L, Orlando G, Guaraldi G, Rochira V.

Eur J Endocrinol. 2014 Apr 10;170(5):685-96. doi: 10.1530/EJE-13-0961. Print 2014 May.


Anthropometry, CT, and DXA as predictors of GH deficiency in premenopausal women: ROC curve analysis.

Bredella MA, Utz AL, Torriani M, Thomas B, Schoenfeld DA, Miller KK.

J Appl Physiol (1985). 2009 Feb;106(2):418-22. doi: 10.1152/japplphysiol.90998.2008. Epub 2008 Dec 18.


Insulin sensitivity and β-cell function in adults with lifetime, untreated isolated growth hormone deficiency.

Oliveira CR, Salvatori R, Barreto-Filho JA, Rocha IE, Mari A, Pereira RM, Campos VC, Menezes M, Gomes E, Meneguz-Moreno RA, Araújo VP, Leite NT, Nascimento-Junior AC, Farias MI, Viscente TA, Araújo RD, Melo EV, Aguiar-Oliveira MH.

J Clin Endocrinol Metab. 2012 Mar;97(3):1013-9. doi: 10.1210/jc.2011-2590. Epub 2011 Dec 14.


Elderly people with hypothalamic-pituitary disease and growth hormone deficiency: lipid profiles, body composition and quality of life compared with control subjects.

Li Voon Chong JS, Benbow S, Foy P, Wallymahmed ME, Wile D, MacFarlane IA.

Clin Endocrinol (Oxf). 2000 Nov;53(5):551-9.


The effect of GH replacement therapy on different fat compartments: a whole-body magnetic resonance imaging study.

Egger A, Buehler T, Boesch C, Diem P, Stettler C, Christ ER.

Eur J Endocrinol. 2011 Jan;164(1):23-9. doi: 10.1530/EJE-10-0702. Epub 2010 Oct 7.


A history of cranial radiotherapy is associated with a higher visceral to subcutaneous fat ratio in men with pituitary insufficiency.

Borgers AJ, Alkemade A, Venema HW, Fliers E, Bisschop PH.

Eur J Endocrinol. 2012 Apr;166(4):619-24. doi: 10.1530/EJE-11-1023. Epub 2012 Jan 12.


Adult height in patients with permanent growth hormone deficiency with and without multiple pituitary hormone deficiencies.

Maghnie M, Ambrosini L, Cappa M, Pozzobon G, Ghizzoni L, Ubertini MG, di Iorgi N, Tinelli C, Pilia S, Chiumello G, Lorini R, Loche S.

J Clin Endocrinol Metab. 2006 Aug;91(8):2900-5. Epub 2006 May 9.


A 360-degree overview of body composition in healthy people: relationships among anthropometry, ultrasonography, and dual-energy x-ray absorptiometry.

Bazzocchi A, Diano D, Ponti F, Salizzoni E, Albisinni U, Marchesini G, Battista G.

Nutrition. 2014 Jun;30(6):696-701. doi: 10.1016/j.nut.2013.11.013. Epub 2013 Dec 3.


Lifetime, untreated isolated GH deficiency due to a GH-releasing hormone receptor mutation has beneficial consequences on bone status in older individuals, and does not influence their abdominal aorta calcification.

Souza AH, Farias MI, Salvatori R, Silva GM, Santana JA, Pereira FA, de Paula FJ, Valença EH, Melo EV, Barbosa RA, Pereira RM, Gois-Junior MB, Aguiar-Oliveira MH.

Endocrine. 2014 Sep;47(1):191-7. doi: 10.1007/s12020-013-0118-5. Epub 2013 Nov 23.


Association of fat to lean mass ratio with metabolic dysfunction in women with polycystic ovary syndrome.

Ezeh U, Pall M, Mathur R, Azziz R.

Hum Reprod. 2014 Jul;29(7):1508-17. Epub 2014 May 9.

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