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Items: 1 to 20 of 88

1.

Virology. Response to Comment on "Specific and nonhepatotoxic degradation of nuclear hepatitis B virus cccDNA".

Xia Y, Lucifora J, Reisinger F, Heikenwalder M, Protzer U.

Science. 2014 Jun 13;344(6189):1237. doi: 10.1126/science.1254083.

2.

Virology. Comment on "Specific and nonhepatotoxic degradation of nuclear hepatitis B virus cccDNA".

Chisari FV, Mason WS, Seeger C.

Science. 2014 Jun 13;344(6189):1237. doi: 10.1126/science.1254082.

3.

Cytidine deamination and cccDNA degradation: A new approach for curing HBV?

Ding S, Robek MD.

Hepatology. 2014 Dec;60(6):2118-21. doi: 10.1002/hep.27386. Epub 2014 Oct 29. No abstract available.

PMID:
25142126
4.

Specific and nonhepatotoxic degradation of nuclear hepatitis B virus cccDNA.

Lucifora J, Xia Y, Reisinger F, Zhang K, Stadler D, Cheng X, Sprinzl MF, Koppensteiner H, Makowska Z, Volz T, Remouchamps C, Chou WM, Thasler WE, Hüser N, Durantel D, Liang TJ, Münk C, Heim MH, Browning JL, Dejardin E, Dandri M, Schindler M, Heikenwalder M, Protzer U.

Science. 2014 Mar 14;343(6176):1221-8. doi: 10.1126/science.1243462. Epub 2014 Feb 20.

PMID:
24557838
5.

Virology. Getting rid of a persistent troublemaker to cure hepatitis.

Shlomai A, Rice CM.

Science. 2014 Mar 14;343(6176):1212-3. doi: 10.1126/science.1252186. No abstract available.

PMID:
24626921
6.

Identification of disubstituted sulfonamide compounds as specific inhibitors of hepatitis B virus covalently closed circular DNA formation.

Cai D, Mills C, Yu W, Yan R, Aldrich CE, Saputelli JR, Mason WS, Xu X, Guo JT, Block TM, Cuconati A, Guo H.

Antimicrob Agents Chemother. 2012 Aug;56(8):4277-88. doi: 10.1128/AAC.00473-12. Epub 2012 May 29.

7.

Formation of covalently closed circular DNA in Hep38.7-Tet cells, a tetracycline inducible hepatitis B virus expression cell line.

Ogura N, Watashi K, Noguchi T, Wakita T.

Biochem Biophys Res Commun. 2014 Sep 26;452(3):315-21. doi: 10.1016/j.bbrc.2014.08.029. Epub 2014 Aug 20.

PMID:
25150444
8.

In vivo proliferation of hepadnavirus-infected hepatocytes induces loss of covalently closed circular DNA in mice.

Lutgehetmann M, Volz T, Köpke A, Broja T, Tigges E, Lohse AW, Fuchs E, Murray JM, Petersen J, Dandri M.

Hepatology. 2010 Jul;52(1):16-24. doi: 10.1002/hep.23611.

PMID:
20578126
9.

Targeting hepatitis B virus cccDNA by CRISPR/Cas9 nuclease efficiently inhibits viral replication.

Dong C, Qu L, Wang H, Wei L, Dong Y, Xiong S.

Antiviral Res. 2015 Jun;118:110-7. doi: 10.1016/j.antiviral.2015.03.015. Epub 2015 Apr 3.

PMID:
25843425
10.

[Specific degradation of nuclear hepatitis B virus covalently closed circular DNA].

Lucifora J, Xia Y, Reisinger F, Stadler D, Heikenwälder M, Protzer U.

Med Sci (Paris). 2014 Aug-Sep;30(8-9):724-6. doi: 10.1051/medsci/20143008003. Epub 2014 Sep 1. French. No abstract available.

12.

Interferon-γ and Tumor Necrosis Factor-α Produced by T Cells Reduce the HBV Persistence Form, cccDNA, Without Cytolysis.

Xia Y, Stadler D, Lucifora J, Reisinger F, Webb D, Hösel M, Michler T, Wisskirchen K, Cheng X, Zhang K, Chou WM, Wettengel JM, Malo A, Bohne F, Hoffmann D, Eyer F, Thimme R, Falk CS, Thasler WE, Heikenwalder M, Protzer U.

Gastroenterology. 2016 Jan;150(1):194-205. doi: 10.1053/j.gastro.2015.09.026. Epub 2015 Sep 28.

PMID:
26416327
13.

TGF-β triggers HBV cccDNA degradation through AID-dependent deamination.

Qiao Y, Han X, Guan G, Wu N, Sun J, Pak V, Liang G.

FEBS Lett. 2016 Feb;590(3):419-27. doi: 10.1002/1873-3468.12058. Epub 2016 Feb 2.

14.

Inhibitory effect of adefovir and lamivudine on the initiation of hepatitis B virus infection in primary tupaia hepatocytes.

Köck J, Baumert TF, Delaney WE 4th, Blum HE, von Weizsäcker F.

Hepatology. 2003 Dec;38(6):1410-8.

PMID:
14647052
15.

Control of cccDNA function in hepatitis B virus infection.

Levrero M, Pollicino T, Petersen J, Belloni L, Raimondo G, Dandri M.

J Hepatol. 2009 Sep;51(3):581-92. doi: 10.1016/j.jhep.2009.05.022. Epub 2009 Jun 10. Review.

16.

Hepatitis B virus replication is regulated by the acetylation status of hepatitis B virus cccDNA-bound H3 and H4 histones.

Pollicino T, Belloni L, Raffa G, Pediconi N, Squadrito G, Raimondo G, Levrero M.

Gastroenterology. 2006 Mar;130(3):823-37.

PMID:
16530522
17.

Alpha-interferon suppresses hepadnavirus transcription by altering epigenetic modification of cccDNA minichromosomes.

Liu F, Campagna M, Qi Y, Zhao X, Guo F, Xu C, Li S, Li W, Block TM, Chang J, Guo JT.

PLoS Pathog. 2013 Sep;9(9):e1003613. doi: 10.1371/journal.ppat.1003613. Epub 2013 Sep 12.

19.

Metabolism and function of hepatitis B virus cccDNA: Implications for the development of cccDNA-targeting antiviral therapeutics.

Guo JT, Guo H.

Antiviral Res. 2015 Oct;122:91-100. doi: 10.1016/j.antiviral.2015.08.005. Epub 2015 Aug 10. Review.

20.

Hepatitis B virus limits response of human hepatocytes to interferon-α in chimeric mice.

Lütgehetmann M, Bornscheuer T, Volz T, Allweiss L, Bockmann JH, Pollok JM, Lohse AW, Petersen J, Dandri M.

Gastroenterology. 2011 Jun;140(7):2074-83, 2083.e1-2. doi: 10.1053/j.gastro.2011.02.057. Epub 2011 Mar 2.

PMID:
21376046

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