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Items: 1 to 20 of 145

1.

Impaired cardiac anti-oxidant activity in diabetes: human and correlative experimental studies.

Connelly KA, Advani A, Advani SL, Zhang Y, Kim YM, Shen V, Thai K, Kelly DJ, Gilbert RE.

Acta Diabetol. 2014 Oct;51(5):771-82. doi: 10.1007/s00592-014-0608-9. Epub 2014 Jun 13.

PMID:
24925443
2.

Hyperglycemia promotes oxidative stress through inhibition of thioredoxin function by thioredoxin-interacting protein.

Schulze PC, Yoshioka J, Takahashi T, He Z, King GL, Lee RT.

J Biol Chem. 2004 Jul 16;279(29):30369-74. Epub 2004 May 5.

3.

Expression, localization, and function of the thioredoxin system in diabetic nephropathy.

Advani A, Gilbert RE, Thai K, Gow RM, Langham RG, Cox AJ, Connelly KA, Zhang Y, Herzenberg AM, Christensen PK, Pollock CA, Qi W, Tan SM, Parving HH, Kelly DJ.

J Am Soc Nephrol. 2009 Apr;20(4):730-41. doi: 10.1681/ASN.2008020142. Epub 2009 Feb 11.

5.
6.

Thioredoxin-interacting protein controls cardiac hypertrophy through regulation of thioredoxin activity.

Yoshioka J, Schulze PC, Cupesi M, Sylvan JD, MacGillivray C, Gannon J, Huang H, Lee RT.

Circulation. 2004 Jun 1;109(21):2581-6. Epub 2004 May 3.

7.

Hyperglycemia regulates TXNIP/TRX/ROS axis via p38 MAPK and ERK pathways in pancreatic cancer.

Li W, Wu Z, Ma Q, Liu J, Xu Q, Han L, Duan W, Lv Y, Wang F, Reindl KM, Wu E.

Curr Cancer Drug Targets. 2014;14(4):348-56.

PMID:
24720336
8.

High glucose-induced thioredoxin-interacting protein in renal proximal tubule cells is independent of transforming growth factor-beta1.

Qi W, Chen X, Gilbert RE, Zhang Y, Waltham M, Schache M, Kelly DJ, Pollock CA.

Am J Pathol. 2007 Sep;171(3):744-54. Epub 2007 Aug 3.

9.

Thioredoxin-Interacting Protein Deficiency Protects against Diabetic Nephropathy.

Shah A, Xia L, Masson EA, Gui C, Momen A, Shikatani EA, Husain M, Quaggin S, John R, Fantus IG.

J Am Soc Nephrol. 2015 Dec;26(12):2963-77. doi: 10.1681/ASN.2014050528. Epub 2015 Apr 8.

10.

HECT-Type Ubiquitin E3 Ligase ITCH Interacts With Thioredoxin-Interacting Protein and Ameliorates Reactive Oxygen Species-Induced Cardiotoxicity.

Otaki Y, Takahashi H, Watanabe T, Funayama A, Netsu S, Honda Y, Narumi T, Kadowaki S, Hasegawa H, Honda S, Arimoto T, Shishido T, Miyamoto T, Kamata H, Nakajima O, Kubota I.

J Am Heart Assoc. 2016 Jan 21;5(1). pii: e002485. doi: 10.1161/JAHA.115.002485.

11.

A critical role for thioredoxin-interacting protein in diabetes-related impairment of angiogenesis.

Dunn LL, Simpson PJ, Prosser HC, Lecce L, Yuen GS, Buckle A, Sieveking DP, Vanags LZ, Lim PR, Chow RW, Lam YT, Clayton Z, Bao S, Davies MJ, Stadler N, Celermajer DS, Stocker R, Bursill CA, Cooke JP, Ng MK.

Diabetes. 2014 Feb;63(2):675-87. doi: 10.2337/db13-0417. Epub 2013 Nov 5.

12.

Up-regulation of thioredoxin interacting protein (Txnip) by p38 MAPK and FOXO1 contributes to the impaired thioredoxin activity and increased ROS in glucose-treated endothelial cells.

Li X, Rong Y, Zhang M, Wang XL, LeMaire SA, Coselli JS, Zhang Y, Shen YH.

Biochem Biophys Res Commun. 2009 Apr 17;381(4):660-5. doi: 10.1016/j.bbrc.2009.02.132. Epub 2009 Feb 28.

13.

Thioredoxin-interacting protein mediates high glucose-induced reactive oxygen species generation by mitochondria and the NADPH oxidase, Nox4, in mesangial cells.

Shah A, Xia L, Goldberg H, Lee KW, Quaggin SE, Fantus IG.

J Biol Chem. 2013 Mar 8;288(10):6835-48. doi: 10.1074/jbc.M112.419101. Epub 2013 Jan 17.

14.

Quercetin and allopurinol reduce liver thioredoxin-interacting protein to alleviate inflammation and lipid accumulation in diabetic rats.

Wang W, Wang C, Ding XQ, Pan Y, Gu TT, Wang MX, Liu YL, Wang FM, Wang SJ, Kong LD.

Br J Pharmacol. 2013 Jul;169(6):1352-71. doi: 10.1111/bph.12226.

15.

Diabetes impairs exercise training-associated thioredoxin response and glutathione status in rat brain.

Lappalainen Z, Lappalainen J, Oksala NK, Laaksonen DE, Khanna S, Sen CK, Atalay M.

J Appl Physiol (1985). 2009 Feb;106(2):461-7. doi: 10.1152/japplphysiol.91252.2008. Epub 2008 Dec 12.

16.

Transcription factors Kr├╝ppel-like factor 6 and peroxisome proliferator-activated receptor-{gamma} mediate high glucose-induced thioredoxin-interacting protein.

Qi W, Chen X, Holian J, Tan CY, Kelly DJ, Pollock CA.

Am J Pathol. 2009 Nov;175(5):1858-67. doi: 10.2353/ajpath.2009.090263. Epub 2009 Oct 1.

17.

High beta-cell mass prevents streptozotocin-induced diabetes in thioredoxin-interacting protein-deficient mice.

Masson E, Koren S, Razik F, Goldberg H, Kwan EP, Sheu L, Gaisano HY, Fantus IG.

Am J Physiol Endocrinol Metab. 2009 Jun;296(6):E1251-61. doi: 10.1152/ajpendo.90619.2008. Epub 2009 Feb 17.

18.

p38 MAPK pathway is involved in high glucose-induced thioredoxin interacting protein induction in mouse mesangial cells.

Ren Y, Shi Y, Wang Y, Li Y, Wu S, Li H, Zhang Y, Duan H.

FEBS Lett. 2010 Aug 4;584(15):3480-5. doi: 10.1016/j.febslet.2010.07.010. Epub 2010 Jul 15.

19.

Possible role for the thioredoxin system in the protective effects of probucol in the pancreatic islets of diabetic rats.

Liu JH, Liu DF, Wang NN, Lin HL, Mei X.

Clin Exp Pharmacol Physiol. 2011 Aug;38(8):528-33. doi: 10.1111/j.1440-1681.2011.05545.x.

PMID:
21615774
20.

Decreasing Txnip mRNA and protein levels in pancreatic MIN6 cells reduces reactive oxygen species and restores glucose regulated insulin secretion.

Rani S, Mehta JP, Barron N, Doolan P, Jeppesen PB, Clynes M, O'Driscoll L.

Cell Physiol Biochem. 2010;25(6):667-74. doi: 10.1159/000315086. Epub 2010 May 18.

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