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Items: 1 to 20 of 102

1.

Prospects for novel inhibitors of peptidoglycan transglycosylases.

Galley NF, O'Reilly AM, Roper DI.

Bioorg Chem. 2014 Aug;55:16-26. doi: 10.1016/j.bioorg.2014.05.007. Epub 2014 May 21. Review.

2.

Targeting the forgotten transglycosylases.

Halliday J, McKeveney D, Muldoon C, Rajaratnam P, Meutermans W.

Biochem Pharmacol. 2006 Mar 30;71(7):957-67. Epub 2005 Nov 18. Review.

PMID:
16298347
3.

Bacterial transglycosylase inhibitors.

Ostash B, Walker S.

Curr Opin Chem Biol. 2005 Oct;9(5):459-66. Review.

PMID:
16118062
4.

Screen for inhibitors of the coupled transglycosylase-transpeptidase of peptidoglycan biosynthesis in Escherichia coli.

Ramachandran V, Chandrakala B, Kumar VP, Usha V, Solapure SM, de Sousa SM.

Antimicrob Agents Chemother. 2006 Apr;50(4):1425-32.

5.

Targeting Bacterial Cell Wall Peptidoglycan Synthesis by Inhibition of Glycosyltransferase Activity.

Mesleh MF, Rajaratnam P, Conrad M, Chandrasekaran V, Liu CM, Pandya BA, Hwang YS, Rye PT, Muldoon C, Becker B, Zuegg J, Meutermans W, Moy TI.

Chem Biol Drug Des. 2016 Feb;87(2):190-9. doi: 10.1111/cbdd.12662. Epub 2015 Oct 9.

PMID:
26358369
6.

Structural details of the glycosyltransferase step of peptidoglycan assembly.

Lovering AL, Gretes M, Strynadka NC.

Curr Opin Struct Biol. 2008 Oct;18(5):534-43. doi: 10.1016/j.sbi.2008.07.002. Epub 2008 Sep 1. Review.

PMID:
18721881
7.

Scintillation proximity assay for inhibitors of Escherichia coli MurG and, optionally, MraY.

Ravishankar S, Kumar VP, Chandrakala B, Jha RK, Solapure SM, de Sousa SM.

Antimicrob Agents Chemother. 2005 Apr;49(4):1410-8.

8.

[High-throughput screening for inhibitors of bacterial transglycosylase].

Steri R, Schubert-Zsilavecz M.

Pharm Unserer Zeit. 2008;37(4):278-9. doi: 10.1002/pauz.200890044. German. No abstract available.

PMID:
18618623
9.

Vancomycin analogues active against vanA-resistant strains inhibit bacterial transglycosylase without binding substrate.

Chen L, Walker D, Sun B, Hu Y, Walker S, Kahne D.

Proc Natl Acad Sci U S A. 2003 May 13;100(10):5658-63. Epub 2003 Apr 24.

10.

Inhibitors of the peptidoglycan biosynthesis enzymes MurA-F.

Hrast M, Sosič I, Sink R, Gobec S.

Bioorg Chem. 2014 Aug;55:2-15. doi: 10.1016/j.bioorg.2014.03.008. Epub 2014 Apr 2. Review.

PMID:
24755374
11.

A microplate assay for the coupled transglycosylase-transpeptidase activity of the penicillin binding proteins; a vancomycin-neutralizing tripeptide combination prevents penicillin inhibition of peptidoglycan synthesis.

Kumar VP, Basavannacharya C, de Sousa SM.

Biochem Biophys Res Commun. 2014 Jul 18;450(1):347-52. doi: 10.1016/j.bbrc.2014.05.119. Epub 2014 Jun 2.

PMID:
24944023
12.

New continuous fluorometric assay for bacterial transglycosylase using Förster resonance energy transfer.

Huang SH, Wu WS, Huang LY, Huang WF, Fu WC, Chen PT, Fang JM, Cheng WC, Cheng TJ, Wong CH.

J Am Chem Soc. 2013 Nov 13;135(45):17078-89. doi: 10.1021/ja407985m. Epub 2013 Nov 5.

PMID:
24131464
13.

Characterization of a transglycosylase domain of Streptococcus pneumoniae PBP1b.

Liu H, Wong CH.

Bioorg Med Chem. 2006 Nov 1;14(21):7187-95. Epub 2006 Jul 25.

PMID:
16870450
14.

The molecular biology of moenomycins: towards novel antibiotics based on inhibition of bacterial peptidoglycan glycosyltransferases.

Ostash B, Doud E, Fedorenko V.

Biol Chem. 2010 May;391(5):499-504. doi: 10.1515/BC.2010.053. Review.

PMID:
20302515
15.

Small molecule inhibitors of peptidoglycan synthesis targeting the lipid II precursor.

Derouaux A, Turk S, Olrichs NK, Gobec S, Breukink E, Amoroso A, Offant J, Bostock J, Mariner K, Chopra I, Vernet T, Zervosen A, Joris B, Frère JM, Nguyen-Distèche M, Terrak M.

Biochem Pharmacol. 2011 May 1;81(9):1098-105. doi: 10.1016/j.bcp.2011.02.008. Epub 2011 Feb 26.

PMID:
21356201
16.

Crystal structure of a peptidoglycan glycosyltransferase suggests a model for processive glycan chain synthesis.

Yuan Y, Barrett D, Zhang Y, Kahne D, Sliz P, Walker S.

Proc Natl Acad Sci U S A. 2007 Mar 27;104(13):5348-53. Epub 2007 Mar 8.

17.

Synthesis of modified peptidoglycan precursor analogues for the inhibition of glycosyltransferase.

Dumbre S, Derouaux A, Lescrinier E, Piette A, Joris B, Terrak M, Herdewijn P.

J Am Chem Soc. 2012 Jun 6;134(22):9343-51. doi: 10.1021/ja302099u. Epub 2012 May 25.

18.

Monofunctional transglycosylases are not essential for Staphylococcus aureus cell wall synthesis.

Reed P, Veiga H, Jorge AM, Terrak M, Pinho MG.

J Bacteriol. 2011 May;193(10):2549-56. doi: 10.1128/JB.01474-10. Epub 2011 Mar 25.

19.

Muraymycins, novel peptidoglycan biosynthesis inhibitors: synthesis and SAR of their analogues.

Yamashita A, Norton E, Petersen PJ, Rasmussen BA, Singh G, Yang Y, Mansour TS, Ho DM.

Bioorg Med Chem Lett. 2003 Oct 6;13(19):3345-50.

PMID:
12951123
20.

Crystal structure of the membrane-bound bifunctional transglycosylase PBP1b from Escherichia coli.

Sung MT, Lai YT, Huang CY, Chou LY, Shih HW, Cheng WC, Wong CH, Ma C.

Proc Natl Acad Sci U S A. 2009 Jun 2;106(22):8824-9. doi: 10.1073/pnas.0904030106. Epub 2009 May 19.

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