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p27(kip1) deficiency accelerates dentin and alveolar bone formation.

Yin Y, Wang Q, Sun W, Wang Y, Chen N, Miao D.

Clin Exp Pharmacol Physiol. 2014 Oct;41(10):807-16. doi: 10.1111/1440-1681.12276.


CBX7 deficiency plays a positive role in dentin and alveolar bone development.

Zhou Z, Yin Y, Jiang F, Niu Y, Wan S, Chen N, Shen M.

J Mol Histol. 2016 Aug;47(4):401-11. doi: 10.1007/s10735-016-9682-3. Epub 2016 Jun 7.


PTHrP Nuclear Localization and Carboxyl Terminus Sequences Modulate Dental and Mandibular Development in Part via the Action of p27.

Sun W, Wu J, Huang L, Liu H, Wang R, Karaplis A, Goltzman D, Miao D.

Endocrinology. 2016 Apr;157(4):1372-84. doi: 10.1210/en.2015-1555. Epub 2016 Feb 9.


The p27 Pathway Modulates the Regulation of Skeletal Growth and Osteoblastic Bone Formation by Parathyroid Hormone-Related Peptide.

Zhu M, Zhang J, Dong Z, Zhang Y, Wang R, Karaplis A, Goltzman D, Miao D.

J Bone Miner Res. 2015 Nov;30(11):1969-79. doi: 10.1002/jbmr.2544. Epub 2015 Jun 30.


Distinctive anabolic roles of 1,25-dihydroxyvitamin D(3) and parathyroid hormone in teeth and mandible versus long bones.

Liu H, Guo J, Wang L, Chen N, Karaplis A, Goltzman D, Miao D.

J Endocrinol. 2009 Nov;203(2):203-13. doi: 10.1677/JOE-09-0247. Epub 2009 Aug 27.


Bmi1 plays an important role in dentin and mandible homeostasis by maintaining redox balance.

Yin Y, Xue X, Wang Q, Chen N, Miao D.

Am J Transl Res. 2016 Nov 15;8(11):4716-4725. eCollection 2016.


Fibroblast growth factor 23 overexpression impacts negatively on dentin mineralization and dentinogenesis in mice.

Chen L, Liu H, Sun W, Bai X, Karaplis AC, Goltzman D, Miao D.

Clin Exp Pharmacol Physiol. 2011 Jun;38(6):395-402. doi: 10.1111/j.1440-1681.2011.05526.x.


Osteoblast-targeted overexpression of TAZ increases bone mass in vivo.

Yang JY, Cho SW, An JH, Jung JY, Kim SW, Kim SY, Kim JE, Shin CS.

PLoS One. 2013;8(2):e56585. doi: 10.1371/journal.pone.0056585. Epub 2013 Feb 18.


Deficiency of adiponectin protects against ovariectomy-induced osteoporosis in mice.

Wang F, Wang PX, Wu XL, Dang SY, Chen Y, Ni YY, Gao LH, Lu SY, Kuang Y, Huang L, Fei J, Wang ZG, Pang XF.

PLoS One. 2013 Jul 2;8(7):e68497. doi: 10.1371/journal.pone.0068497. Print 2013.


BMP2 regulates Osterix through Msx2 and Runx2 during osteoblast differentiation.

Matsubara T, Kida K, Yamaguchi A, Hata K, Ichida F, Meguro H, Aburatani H, Nishimura R, Yoneda T.

J Biol Chem. 2008 Oct 24;283(43):29119-25. doi: 10.1074/jbc.M801774200. Epub 2008 Aug 14.


Osteogenic activity of silymarin through enhancement of alkaline phosphatase and osteocalcin in osteoblasts and tibia-fractured mice.

Kim JL, Park SH, Jeong D, Nam JS, Kang YH.

Exp Biol Med (Maywood). 2012 Apr;237(4):417-28. doi: 10.1258/ebm.2011.011376. Epub 2012 Apr 10.


Alterations in phosphorus, calcium and PTHrP contribute to defects in dental and dental alveolar bone formation in calcium-sensing receptor-deficient mice.

Sun W, Sun W, Liu J, Zhou X, Xiao Y, Karaplis A, Pollak MR, Brown E, Goltzman D, Miao D.

Development. 2010 Mar;137(6):985-92. doi: 10.1242/dev.045898. Epub 2010 Feb 11.


Accelerated bone formation and increased osteoblast number contribute to the abnormal tooth germ development in parathyroid hormone-related protein knockout mice.

Kitahara Y, Suda N, Terashima T, Baba O, Mekaapiruk K, Hammond VE, Takano Y, Ohyama K.

Bone. 2004 Nov;35(5):1100-6.


Osteoblast proliferation and differentiation on dentin slices are modulated by pretreatment of the surface with tetracycline or osteoclasts.

Schwartz Z, Lohmann CH, Wieland M, Cochran DL, Dean DD, Textor M, Bonewald LF, Boyan BD.

J Periodontol. 2000 Apr;71(4):586-97.


Juvenile dermatomyositis calcifications selectively displayed markers of bone formation.

Urganus AL, Zhao YD, Pachman LM.

Arthritis Rheum. 2009 Apr 15;61(4):501-8. doi: 10.1002/art.24391.


Heterodimeric BMP-2/7 antagonizes the inhibition of all-trans retinoic acid and promotes the osteoblastogenesis.

Bi W, Gu Z, Zheng Y, Zhang X, Guo J, Wu G.

PLoS One. 2013 Oct 30;8(10):e78198. doi: 10.1371/journal.pone.0078198. eCollection 2013.


A cell line with characteristics of the periodontal ligament fibroblasts is negatively regulated for mineralization and Runx2/Cbfa1/Osf2 activity, part of which can be overcome by bone morphogenetic protein-2.

Saito Y, Yoshizawa T, Takizawa F, Ikegame M, Ishibashi O, Okuda K, Hara K, Ishibashi K, Obinata M, Kawashima H.

J Cell Sci. 2002 Nov 1;115(Pt 21):4191-200.


Cherubism gene Sh3bp2 is important for optimal bone formation, osteoblast differentiation, and function.

Mukherjee PM, Wang CJ, Chen IP, Jafarov T, Olsen BR, Ueki Y, Reichenberger EJ.

Am J Orthod Dentofacial Orthop. 2010 Aug;138(2):140.e1-140.e11; discussion 140-1. doi: 10.1016/j.ajodo.2009.05.021.


Positive regulation of osteogenesis by bile acid through FXR.

Cho SW, An JH, Park H, Yang JY, Choi HJ, Kim SW, Park YJ, Kim SY, Yim M, Baek WY, Kim JE, Shin CS.

J Bone Miner Res. 2013 Oct;28(10):2109-21. doi: 10.1002/jbmr.1961.

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