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Items: 1 to 20 of 263

1.

miR-185 inhibits hepatocellular carcinoma growth by targeting the DNMT1/PTEN/Akt pathway.

Qadir XV, Han C, Lu D, Zhang J, Wu T.

Am J Pathol. 2014 Aug;184(8):2355-64. doi: 10.1016/j.ajpath.2014.05.004. Epub 2014 Jun 6.

2.

Overexpression of microRNA-30a-5p inhibits liver cancer cell proliferation and induces apoptosis by targeting MTDH/PTEN/AKT pathway.

Li WF, Dai H, Ou Q, Zuo GQ, Liu CA.

Tumour Biol. 2016 May;37(5):5885-95. doi: 10.1007/s13277-015-4456-1. Epub 2015 Nov 21.

PMID:
26589417
3.

MicroRNA-155-5p promotes hepatocellular carcinoma progression by suppressing PTEN through the PI3K/Akt pathway.

Fu X, Wen H, Jing L, Yang Y, Wang W, Liang X, Nan K, Yao Y, Tian T.

Cancer Sci. 2017 Apr;108(4):620-631. doi: 10.1111/cas.13177. Epub 2017 Apr 19.

4.

miR-218 modulate hepatocellular carcinoma cell proliferation through PTEN/AKT/PI3K pathway and HoxA10.

Xiao ZD, Jiao CY, Huang HT, He LJ, Zhao JJ, Lu ZY, Liu LX.

Int J Clin Exp Pathol. 2014 Jun 15;7(7):4039-44. eCollection 2014.

5.

MiR-21 mediates sorafenib resistance of hepatocellular carcinoma cells by inhibiting autophagy via the PTEN/Akt pathway.

He C, Dong X, Zhai B, Jiang X, Dong D, Li B, Jiang H, Xu S, Sun X.

Oncotarget. 2015 Oct 6;6(30):28867-81. doi: 10.18632/oncotarget.4814.

6.

MicroRNA-93 activates c-Met/PI3K/Akt pathway activity in hepatocellular carcinoma by directly inhibiting PTEN and CDKN1A.

Ohta K, Hoshino H, Wang J, Ono S, Iida Y, Hata K, Huang SK, Colquhoun S, Hoon DS.

Oncotarget. 2015 Feb 20;6(5):3211-24.

7.

MiR-20a Induces Cell Radioresistance by Activating the PTEN/PI3K/Akt Signaling Pathway in Hepatocellular Carcinoma.

Zhang Y, Zheng L, Ding Y, Li Q, Wang R, Liu T, Sun Q, Yang H, Peng S, Wang W, Chen L.

Int J Radiat Oncol Biol Phys. 2015 Aug 1;92(5):1132-1140. doi: 10.1016/j.ijrobp.2015.04.007. Epub 2015 Apr 13.

PMID:
26031366
8.

Upregulated microRNA-29a by hepatitis B virus X protein enhances hepatoma cell migration by targeting PTEN in cell culture model.

Kong G, Zhang J, Zhang S, Shan C, Ye L, Zhang X.

PLoS One. 2011 May 5;6(5):e19518. doi: 10.1371/journal.pone.0019518.

9.

MicroRNA-130b promotes proliferation and EMT-induced metastasis via PTEN/p-AKT/HIF-1α signaling.

Chang RM, Xu JF, Fang F, Yang H, Yang LY.

Tumour Biol. 2016 Aug;37(8):10609-19. doi: 10.1007/s13277-016-4919-z. Epub 2016 Feb 10.

PMID:
26861561
10.

MicroRNA-21 suppresses PTEN and hSulf-1 expression and promotes hepatocellular carcinoma progression through AKT/ERK pathways.

Bao L, Yan Y, Xu C, Ji W, Shen S, Xu G, Zeng Y, Sun B, Qian H, Chen L, Wu M, Su C, Chen J.

Cancer Lett. 2013 Sep 1;337(2):226-36. doi: 10.1016/j.canlet.2013.05.007. Epub 2013 May 14.

PMID:
23684551
11.

Comprehensive profiling of novel microRNA-9 targets and a tumor suppressor role of microRNA-9 via targeting IGF2BP1 in hepatocellular carcinoma.

Zhang J, Cheng J, Zeng Z, Wang Y, Li X, Xie Q, Jia J, Yan Y, Guo Z, Gao J, Yao M, Chen X, Lu F.

Oncotarget. 2015 Dec 8;6(39):42040-52. doi: 10.18632/oncotarget.5969.

12.

miR-367 promotes proliferation and invasion of hepatocellular carcinoma cells by negatively regulating PTEN.

Meng X, Lu P, Fan Q.

Biochem Biophys Res Commun. 2016 Jan 29;470(1):187-91. doi: 10.1016/j.bbrc.2016.01.025. Epub 2016 Jan 7.

PMID:
26772880
13.

In hepatocellular carcinoma miR-519d is up-regulated by p53 and DNA hypomethylation and targets CDKN1A/p21, PTEN, AKT3 and TIMP2.

Fornari F, Milazzo M, Chieco P, Negrini M, Marasco E, Capranico G, Mantovani V, Marinello J, Sabbioni S, Callegari E, Cescon M, Ravaioli M, Croce CM, Bolondi L, Gramantieri L.

J Pathol. 2012 Jul;227(3):275-85. doi: 10.1002/path.3995. Epub 2012 Apr 18.

PMID:
22262409
14.

MicroRNA-519a promotes tumor growth by targeting PTEN/PI3K/AKT signaling in hepatocellular carcinoma.

Tu K, Liu Z, Yao B, Han S, Yang W.

Int J Oncol. 2016 Mar;48(3):965-74. doi: 10.3892/ijo.2015.3309. Epub 2015 Dec 28.

15.

Alpha1-ACT Functions as a Tumour Suppressor in Hepatocellular Carcinoma by Inhibiting the PI3K/AKT/mTOR Signalling Pathway via Activation of PTEN.

Zhu H, Liu Q, Tang J, Xie Y, Xu X, Huang R, Zhang Y, Jin K, Sun B.

Cell Physiol Biochem. 2017;41(6):2289-2306. doi: 10.1159/000475648. Epub 2017 Apr 26.

16.

JARID1B promotes metastasis and epithelial-mesenchymal transition via PTEN/AKT signaling in hepatocellular carcinoma cells.

Tang B, Qi G, Tang F, Yuan S, Wang Z, Liang X, Li B, Yu S, Liu J, Huang Q, Wei Y, Zhai R, Lei B, Yu H, Jiao X, He S.

Oncotarget. 2015 May 20;6(14):12723-39.

17.

MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer.

Meng F, Henson R, Wehbe-Janek H, Ghoshal K, Jacob ST, Patel T.

Gastroenterology. 2007 Aug;133(2):647-58. Epub 2007 May 21.

18.

microRNA-29a suppresses cell proliferation by targeting SPARC in hepatocellular carcinoma.

Zhu XC, Dong QZ, Zhang XF, Deng B, Jia HL, Ye QH, Qin LX, Wu XZ.

Int J Mol Med. 2012 Dec;30(6):1321-6. doi: 10.3892/ijmm.2012.1140. Epub 2012 Sep 25.

PMID:
23023935
19.

MicroRNA-148a is silenced by hypermethylation and interacts with DNA methyltransferase 1 in hepatocellular carcinogenesis.

Long XR, He Y, Huang C, Li J.

Int J Oncol. 2014 Jun;44(6):1915-22. doi: 10.3892/ijo.2014.2373. Epub 2014 Apr 8.

PMID:
24714841
20.

MicroRNA-486-5p, which is downregulated in hepatocellular carcinoma, suppresses tumor growth by targeting PIK3R1.

Huang XP, Hou J, Shen XY, Huang CY, Zhang XH, Xie YA, Luo XL.

FEBS J. 2015 Feb;282(3):579-94. doi: 10.1111/febs.13167. Epub 2014 Dec 27.

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