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Acute high-level exposure to WTC particles alters expression of genes associated with oxidative stress and immune function in the lung.

Cohen MD, Vaughan JM, Garrett B, Prophete C, Horton L, Sisco M, Kodavanti UP, Ward WO, Peltier RE, Zelikoff J, Chen LC.

J Immunotoxicol. 2015 Apr-Jun;12(2):140-53. doi: 10.3109/1547691X.2014.914609. Epub 2014 Jun 9.


Impact of acute exposure to WTC dust on ciliated and goblet cells in lungs of rats.

Cohen MD, Vaughan JM, Garrett B, Prophete C, Horton L, Sisco M, Ghio A, Zelikoff J, Lung-chi C.

Inhal Toxicol. 2015;27(7):354-61. doi: 10.3109/08958378.2015.1054531. Epub 2015 Jul 21.


A novel system to generate WTC dust particles for inhalation exposures.

Vaughan JM, Garrett BJ, Prophete C, Horton L, Sisco M, Soukup JM, Zelikoff JT, Ghio A, Peltier RE, Asgharian B, Chen LC, Cohen MD.

J Expo Sci Environ Epidemiol. 2014 Jan-Feb;24(1):105-12. doi: 10.1038/jes.2013.68. Epub 2013 Nov 13.


Roles of MAPK pathway activation during cytokine induction in BEAS-2B cells exposed to fine World Trade Center (WTC) dust.

Wang S, Prophete C, Soukup JM, Chen LC, Costa M, Ghio A, Qu Q, Cohen MD, Chen H.

J Immunotoxicol. 2010 Oct-Dec;7(4):298-307. doi: 10.3109/1547691X.2010.509289. Epub 2010 Aug 24.


Interactive effect of cigarette smoke extract and world trade center dust particles on airway cell cytotoxicity.

Xu A, Prophete C, Chen LC, Emala CW, Cohen MD.

J Toxicol Environ Health A. 2011;74(14):887-902. doi: 10.1080/15287394.2011.573719.


World Trade Center (WTC) dust exposure in mice is associated with inflammation, oxidative stress and epigenetic changes in the lung.

Sunil VR, Vayas KN, Fang M, Zarbl H, Massa C, Gow AJ, Cervelli JA, Kipen H, Laumbach RJ, Lioy PJ, Laskin JD, Laskin DL.

Exp Mol Pathol. 2017 Feb;102(1):50-58. doi: 10.1016/j.yexmp.2016.12.005. Epub 2016 Dec 13.


Case report: Lung disease in World Trade Center responders exposed to dust and smoke: carbon nanotubes found in the lungs of World Trade Center patients and dust samples.

Wu M, Gordon RE, Herbert R, Padilla M, Moline J, Mendelson D, Litle V, Travis WD, Gil J.

Environ Health Perspect. 2010 Apr;118(4):499-504. doi: 10.1289/ehp.0901159.


Effects of concentrated ambient particles on normal and hypersecretory airways in rats.

Harkema JR, Keeler G, Wagner J, Morishita M, Timm E, Hotchkiss J, Marsik F, Dvonch T, Kaminski N, Barr E.

Res Rep Health Eff Inst. 2004 Aug;(120):1-68; discussion 69-79.


Residual indoor contamination from world trade center rubble fires as indicated by polycyclic aromatic hydrocarbon profiles.

Pleil JD, Funk WE, Rappaport SM.

Environ Sci Technol. 2006 Feb 15;40(4):1172-7.


Health and environmental consequences of the world trade center disaster.

Landrigan PJ, Lioy PJ, Thurston G, Berkowitz G, Chen LC, Chillrud SN, Gavett SH, Georgopoulos PG, Geyh AS, Levin S, Perera F, Rappaport SM, Small C; NIEHS World Trade Center Working Group.

Environ Health Perspect. 2004 May;112(6):731-9. Review.


Induced sputum assessment in New York City firefighters exposed to World Trade Center dust.

Fireman EM, Lerman Y, Ganor E, Greif J, Fireman-Shoresh S, Lioy PJ, Banauch GI, Weiden M, Kelly KJ, Prezant DJ.

Environ Health Perspect. 2004 Nov;112(15):1564-9.


Exposures among pregnant women near the World Trade Center site on 11 September 2001.

Wolff MS, Teitelbaum SL, Lioy PJ, Santella RM, Wang RY, Jones RL, Caldwell KL, Sjödin A, Turner WE, Li W, Georgopoulos P, Berkowitz GS.

Environ Health Perspect. 2005 Jun;113(6):739-48.


Receptor for advanced glycation end-products and World Trade Center particulate induced lung function loss: A case-cohort study and murine model of acute particulate exposure.

Caraher EJ, Kwon S, Haider SH, Crowley G, Lee A, Ebrahim M, Zhang L, Chen LC, Gordon T, Liu M, Prezant DJ, Schmidt AM, Nolan A.

PLoS One. 2017 Sep 19;12(9):e0184331. doi: 10.1371/journal.pone.0184331. eCollection 2017.


Comparison of WTC dust size on macrophage inflammatory cytokine release in vivo and in vitro.

Weiden MD, Naveed B, Kwon S, Segal LN, Cho SJ, Tsukiji J, Kulkarni R, Comfort AL, Kasturiarachchi KJ, Prophete C, Cohen MD, Chen LC, Rom WN, Prezant DJ, Nolan A.

PLoS One. 2012;7(7):e40016. doi: 10.1371/journal.pone.0040016. Epub 2012 Jul 18.


World Trade Center fine particulate matter causes respiratory tract hyperresponsiveness in mice.

Gavett SH, Haykal-Coates N, Highfill JW, Ledbetter AD, Chen LC, Cohen MD, Harkema JR, Wagner JG, Costa DL.

Environ Health Perspect. 2003 Jun;111(7):981-91.


Cardiovascular biomarkers predict susceptibility to lung injury in World Trade Center dust-exposed firefighters.

Weiden MD, Naveed B, Kwon S, Cho SJ, Comfort AL, Prezant DJ, Rom WN, Nolan A.

Eur Respir J. 2013 May;41(5):1023-30. doi: 10.1183/09031936.00077012. Epub 2012 Aug 16.


Potential for diffuse parenchymal lung disease after exposures at World Trade Center Disaster site.

Szeinuk J, Padilla M, de la Hoz RE.

Mt Sinai J Med. 2008 Mar-Apr;75(2):101-7. doi: 10.1002/msj.20025. Review.


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