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Osteophytes, enthesophytes, and high bone mass: a bone-forming triad with potential relevance in osteoarthritis.

Hardcastle SA, Dieppe P, Gregson CL, Arden NK, Spector TD, Hart DJ, Edwards MH, Dennison EM, Cooper C, Williams M, Davey Smith G, Tobias JH.

Arthritis Rheumatol. 2014 Sep;66(9):2429-39. doi: 10.1002/art.38729.


Prevalence of radiographic hip osteoarthritis is increased in high bone mass.

Hardcastle SA, Dieppe P, Gregson CL, Hunter D, Thomas GE, Arden NK, Spector TD, Hart DJ, Laugharne MJ, Clague GA, Edwards MH, Dennison EM, Cooper C, Williams M, Davey Smith G, Tobias JH.

Osteoarthritis Cartilage. 2014 Aug;22(8):1120-8. doi: 10.1016/j.joca.2014.06.007.


Individuals with high bone mass have an increased prevalence of radiographic knee osteoarthritis.

Hardcastle SA, Dieppe P, Gregson CL, Arden NK, Spector TD, Hart DJ, Edwards MH, Dennison EM, Cooper C, Sayers A, Williams M, Davey Smith G, Tobias JH.

Bone. 2015 Feb;71:171-9. doi: 10.1016/j.bone.2014.10.015.


High Bone Mass is associated with bone-forming features of osteoarthritis in non-weight bearing joints independent of body mass index.

Gregson CL, Hardcastle SA, Murphy A, Faber B, Fraser WD, Williams M, Davey Smith G, Tobias JH.

Bone. 2017 Jan 7;97:306-313. doi: 10.1016/j.bone.2017.01.005. [Epub ahead of print]


'Sink or swim': an evaluation of the clinical characteristics of individuals with high bone mass.

Gregson CL, Steel SA, O'Rourke KP, Allan K, Ayuk J, Bhalla A, Clunie G, Crabtree N, Fogelman I, Goodby A, Langman CM, Linton S, Marriott E, McCloskey E, Moss KE, Palferman T, Panthakalam S, Poole KE, Stone MD, Turton J, Wallis D, Warburton S, Wass J, Duncan EL, Brown MA, Davey-Smith G, Tobias JH.

Osteoporos Int. 2012 Feb;23(2):643-54. doi: 10.1007/s00198-011-1603-4.


High bone mass is associated with an increased prevalence of joint replacement: a case-control study.

Hardcastle SA, Gregson CL, Deere KC, Davey Smith G, Dieppe P, Tobias JH.

Rheumatology (Oxford). 2013 Jun;52(6):1042-51. doi: 10.1093/rheumatology/kes411.


[Effect of osteophytes on bone mineral density of female lumbar spine].

Xiao D, Luo Q, He C, Yang L, He H, Wu Y.

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2010 Jun;27(3):586-9. Chinese.


Effect of osteoarthritis in the lumbar spine and hip on bone mineral density and diagnosis of osteoporosis in elderly men and women.

Liu G, Peacock M, Eilam O, Dorulla G, Braunstein E, Johnston CC.

Osteoporos Int. 1997;7(6):564-9.


Analysis of body composition in individuals with high bone mass reveals a marked increase in fat mass in women but not men.

Gregson CL, Paggiosi MA, Crabtree N, Steel SA, McCloskey E, Duncan EL, Fan B, Shepherd JA, Fraser WD, Smith GD, Tobias JH.

J Clin Endocrinol Metab. 2013 Feb;98(2):818-28. doi: 10.1210/jc.2012-3342.


Bone formers: osteophyte and enthesophyte formation are positively associated.

Rogers J, Shepstone L, Dieppe P.

Ann Rheum Dis. 1997 Feb;56(2):85-90.


A cotwin control study of the relationship between hip osteoarthritis and bone mineral density.

Antoniades L, MacGregor AJ, Matson M, Spector TD.

Arthritis Rheum. 2000 Jul;43(7):1450-5.


Elevated circulating Sclerostin concentrations in individuals with high bone mass, with and without LRP5 mutations.

Gregson CL, Poole KE, McCloskey EV, Duncan EL, Rittweger J, Fraser WD, Smith GD, Tobias JH.

J Clin Endocrinol Metab. 2014 Aug;99(8):2897-907. doi: 10.1210/jc.2013-3958. Erratum in: J Clin Endocrinol Metab. 2015 Aug;100(8):3219. J Clin Endocrinol Metab. 2015 Aug;100(8):3219.


The relationship of bone density and fracture to incident and progressive radiographic osteoarthritis of the knee: the Chingford Study.

Hart DJ, Cronin C, Daniels M, Worthy T, Doyle DV, Spector TD.

Arthritis Rheum. 2002 Jan;46(1):92-9.


Bone mineral density is not related to osteophyte formation in osteoarthritis of the hip.

Okano K, Aoyagi K, Chiba K, Motokawa S, Matsumoto T.

J Rheumatol. 2011 Feb;38(2):358-61. doi: 10.3899/jrheum.100533.


A relationship between spinal new bone formation in ankylosing spondylitis and the sonographically determined Achilles tendon enthesophytes.

Aydin SZ, Can M, Alibaz-Oner F, Keser G, Kurum E, Inal V, Yazisiz V, Birlik M, Emmungil H, Atagunduz P, Direskeneli H, McGonagle D, Pay S.

Rheumatol Int. 2016 Mar;36(3):397-404. doi: 10.1007/s00296-015-3360-8.


Hand bone midshaft enthesophytes: the influence of age, sex, and heritability.

Kalichman L, Malkin I, Kobyliansky E.

Osteoarthritis Cartilage. 2007 Oct;15(10):1113-9.


Bone mineral density and risk of incident and progressive radiographic knee osteoarthritis in women: the Framingham Study.

Zhang Y, Hannan MT, Chaisson CE, McAlindon TE, Evans SR, Aliabadi P, Levy D, Felson DT.

J Rheumatol. 2000 Apr;27(4):1032-7.


Relation of hand enthesophytes with knee enthesopathy: is osteoarthritis related to a systemic enthesopathy?

Gibson N, Guermazi A, Clancy M, Niu J, Grayson P, Aliabadi P, Roemer F, Felson DT.

J Rheumatol. 2012 Feb;39(2):359-64. doi: 10.3899/jrheum.110718.


Disc space narrowing is associated with an increased vertebral fracture risk in postmenopausal women: the OFELY Study.

Sornay-Rendu E, Munoz F, Duboeuf F, Delmas PD; OFELY Study..

J Bone Miner Res. 2004 Dec;19(12):1994-9.


Knee and hip radiographic osteoarthritis predict total hip bone loss in older adults: a prospective study.

Ding C, Cicuttini F, Boon C, Boon P, Srikanth V, Cooley H, Jones G.

J Bone Miner Res. 2010 Apr;25(4):858-65. doi: 10.1359/jbmr.091012.

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